Background:Osteosarcoma is the most common malignant primary bone tumor.The prognosis for patients with disseminated disease remains very poor despite recent advancements in chemotherapy.Moreover,current treatment reg...
supported by the Chinese National Natural Science Foundation of China(grant number:31970502);the National Key Research and Development Program of China(2021YFC2301701,2020ZX10001-016-003 and ZX10304402-003-006).
Taurolidine(TRD),a derivative of taurine,has anti-bacterial and anti-tumor effects by chemically reacting with cell-walls,endotoxins and exotoxins to inhibit the adhesion of microorganisms.However,its application in a...