FLAGELLA

作品数：24被引量：62H指数：5
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相关领域：生物学更多>>
相关作者：杨慎敏郭艳更多>>
相关机构：天津医科大学苏州市立医院苏州大学清华大学更多>>
相关期刊：《Open Journal of Genetics》《Science China(Life Sciences)》《Frontiers in Biology》《World Journal of Gastroenterology》更多>>
相关基金：国家自然科学基金World Health Organization泰国研究基金国家重点基础研究发展计划更多>>
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Gene-knockout by iSTOP enables rapid reproductive disease modeling and phenotyping in germ cells of the founder generation被引量：4
《Science China(Life Sciences)》2024年第5期1035-1050,共16页Yaling Wang Jingwen Chen Xueying Huang Bangguo Wu Peng Dai Feng Zhang Jinsong Li Lingbo Wang 
supported by the National Key Research and Development Program of China(2021YFC2701400);the National Natural Science Foundation of China(32000393,32322017,32288101)。
Cytosine base editing achieves C·G-to-T·A substitutions and can convert four codons(CAA/CAG/CGA/TGG)into STOP-codons(induction of STOP-codons,iSTOP)to knock out genes with reduced mosaicism.iSTOP enables direct phen...
关键词：disease modeling INFERTILITY multiple morphological abnormalities of the flagella(MMAF) induction of STOP-codons(iSTOP CRISPR-STOP) sperm motility 
Coiled-coil domain-containing 38 is required for acrosome biogenesis and fibrous sheath assembly in mice被引量：2
《Journal of Genetics and Genomics》2024年第4期407-418,共12页Yaling Wang Xueying Huang Guoying Sun Jingwen Chen Bangguo Wu Jiahui Luo Shuyan Tang Peng Dai Feng Zhang Jinsong Li Lingbo Wang 
supported by the National Key Research and Development Program of China(2021YFC2701400);in part by the National Natural Science Foundation of China(32000393 and 32288101).
During spermiogenesis,haploid spermatids undergo dramatic morphological changes to form slender sperm flagella and cap-like acrosomes,which are required for successful fertilization.Severe deformities in flagella caus...
关键词：Acrosomal hypoplasia Multiple morphological abnormalities of the flagella(MMAF) INFERTILITY Sperm motility Asthenoteratozoospermia Disease modeling 
Enhancement of astaxanthin accumulation via energy reassignment by removing the flagella of Haematococcus pluvialis
《Bioresources and Bioprocessing》2024年第1期1041-1046,共6页Yuyong Hou Zhile Guo Zhiyong Liu Suihao Yan Meijie Cui Fangjian Chen Weijie Wang Longjiang Yu Lei Zhao 
supported by the National Key R&D Program of China(2022YFC3401803);the Strategic Priority Research Program of Chinese Academy of Sciences(XDC0120301);the Hundred Talents Program of the Chinese Academy of Sciences(E3J56201);the Science and Technology Partnership Program,Ministry of Science and Technology of China(KY202001017);the Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(TSBICIP-IJCP-001,TSBICIP-IJCP-002,TSBICIP-CXRC-027).
Astaxanthin biosynthesis in Haematococcus pluvialis is driven by energy.However,the effect of the flagella-mediated energy-consuming movement process on astaxanthin accumulation has not been well studied.In this study...
关键词：Haematococcus pluvialis ASTAXANTHIN FLAGELLA Energy flow pH-shock 
Study of the Climbing Behavior of the Flagella of Calamus Simplicifolius Based on Micro-CT and Nanoindentation
《Journal of Bionic Engineering》2022年第6期1790-1796,共7页Fukuan Dai Ziwei Wang Tuhua Zhong Hankun Wang Genlin Tian 
Basic Scientific Research Funds of the National Natural Science Foundation(Grant No.31800476);International Center for Bamboo and Rattan(Grant No.1632020011).
Rattan is a typical tropical climbing plant that uses flagella to climb supports to grow.A comprehensive understanding of the anatomic structure and micromechanics of rattan flagella might inspire more research on bio...
关键词：Calamus simplicifolius Micromechanical properties Structure FLAGELLUM BIOMATERIALS 
Novel biallelic loss-of-function mutations in CFAP43 cause multiple morphological abnormalities of the sperm flagellum in Pakistani families被引量：2
《Asian Journal of Andrology》2021年第6期627-632,共6页Ihsan Khan Basit Shah Sobia Dil Nadeem Ullah Jian-Teng Zhou Da-Ren Zhao Yuan-Wei Zhang Xiao-Hua Jiang Ranjha Khan Asad Khan Haider Ali Muhammad Zubair Wasim Shah Huan Zhang Qing-Hua Shi 
This work was supported by the National Natural Science Foundation of China(No.32070850);the National Natural Science Foundation of China(No.31630050,31890780,and 32061143006);the National Key Research and Developmental Program of China(2018YFC1003900,2019YFA0802600,and 2016YFC1000600);the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB19000000);the Fundamental Research Funds for the Central Universities(No.YD2070002006).
Multiple morphological abnormalities of the sperm flagella(MMAF)is a specific type of asthenoteratozoospermia,presenting with multiple morphological anomalies in spermatozoa,such as absent,bent,coiled,short,or irregul...
关键词：cilia and flagella-associated proteins male infertility multiple morphological abnormalities of the sperm flagella whole-exome sequencing 
Salmonella flagella confer anti-tumor immunological effect via activating Flagellin/TLR5 signalling within tumor microenvironment被引量：9
《Acta Pharmaceutica Sinica B》2021年第10期3165-3177,共13页Jianxiang Chen Yiting Qiao Guo Chen Cunjie Chang Heng Dong Bo Tang Xiawei Cheng Xiufeng Liu Zichun Hua 
supported by grants from the Jiangsu Provincial Nature Science Foundation(BK20192005,China);National Natural Science Foundation of China(81630092,81903143,81802338,and 82072646);Zhejiang Provincial Natural Science Foundation of China for Distinguished Young Scholars(LR21H160001);Start-up Grant of HZNU(4125C5021820470,China)。
Salmonella:mediated cancer therapy has achieved remarkable anti-tumor effects in experimental animal models,but the detailed mechanism remains unsolved.In this report,the active involvement of the host immune response...
关键词：Bacteria-mediated cancer therapy SALMONELLA VNP20009 FLAGELLUM FLAGELLIN TLR5 NF-kB Cancer immune therapy 
Absence of murine CFAP61 causes male infertility due to multiple morphological abnormalities of the flagella被引量：1
《Science Bulletin》2020年第10期854-864,M0004,共12页Tao Huang Yingying Yin Chao Liu Mengjing Li Xiaochen Yu Xiuge Wang Haobo Zhang Tahir Muhammad Fei Gao Wei Li Zi-Jiang Chen Hongbin Liu Jinlong Ma 
We thank Zhang Jie for her assistance in confocal analysis(Advanced Medical Research Institute,Shandong University).This work was supported by the National Key Research and Development Programs of China(2018YFC1003400);the Young Scholars Program of Shandong University(2016WLJH50);the Natural Science Foundation of Shandong Province(ZR2017MH049).
Impaired flagellar development and impaired motility of sperm is a cause of infertility in males. Several genes, including those of the AKAP, CCDC, CFAP, and DNAH families, among others, are involved in the‘‘multipl...
关键词：Multiple morphological abnormalities of the flagella(MMAF) Male infertility Cfap61 Flagellum development 
GadE regulates fliC gene transcription and motility in Escherichia coli被引量：1
《World Journal of Clinical Infectious Diseases》2020年第1期14-23,共10页William R Schwan Nicole L Flohr Abigail R Multerer Jordan C Starkey 
the National Institutes of Health,No.1R15AI-065432.
BACKGROUND Escherichia coli(E.coli)express flagella to ascend human urinary tracts.To survive in the acidic pH of human urine,E.coli uses the glutamate decarboxylase acid response system,which is regulated by the GadE...
关键词：ESCHERICHIA COLI FLAGELLA GadE MOTILITY Acid response FLIC 
Characterization of dominant giant rod-shaped magnetotactic bacteria from a low tide zone of the China Sea
《Journal of Oceanology and Limnology》2018年第3期783-794,共12页TENG Zhaojie ZHANG Wenyan CHEN Yiran PAN Hongmiao XIAO Tian WU Long-Fei 
Supported by the National Natural Science Foundation of China(Nos.41330962,41276170);the National Natural Science Foundation of China-Shandong Joint Fund for Marine Science Research Centers(No.U1606404)
Magnetotactic bacteria are a group of Gram-negative bacteria that synthesize magnetic crystals, enabling them to navigate in relation to magnetic field lines. Morphologies of magnetotactic bacteria include spirillum, ...
关键词：Alphaproteobacteria flagella motility rod-shaped magnetotactic bacteria 
The impacts of a fliD mutation on the biofilm formation of Helicobacter pylori被引量：1
《Asian Pacific Journal of Tropical Biomedicine》2016年第12期1008-1014,共7页Panan Ratthawongjirakul Vorraruthai Thongkerd Wanpen Chaicumpa 
Supported by the Thailand Research Fund(MRG5580161);the Research Fund Project(ASHCU57002);the Faculty of Allied Health Sciences at Chulalongkorn University;the Graduate School Thesis Grant of Chulalongkorn University
Objective:To investigate the impact of the fliD gene on the biofilm formation of Helicobacter pylori(H.pylori).Methods:H.pylori fliD mutant was constructed using inverse PCR mutagenesis.The mobility of the bacteria an...
关键词：Helicobacter pylori BIOFILM FLAGELLA fliD 
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