FLAGELLUM

作品数：16被引量：22H指数：2
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相关作者：李荣生刘海桑更多>>
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The role of SLC26A8 homozygous variants in male infertility and flagellum abnormalities
《Asian Journal of Andrology》2024年第5期544-546,共3页Bin Mao Sha-Sha Zhang Liang-Tao Zhao Hui-Rong Huang Feng-Die Ma Wen-Jing Shi Shan Li Zi-Yan Nie Han-Dan Xiao Xiao-Dong Xie Pei-Qiang Li 
support from grants provided by the Gansu Provincial Natural Science Foundation of China(23JRRA1046);the Gansu Association for Science and Technology(GSHZTS 2022-04);the National College Student Innovation and Entrepreneurship Training Program(202310730222).
Dear Editor,Solute carrier family 26 member 8(SLC26A8)gene belongs to the solute carrier 26(SLC26)family.It demonstrates distinct expression in male spermatozoa.This gene potentially plays a role in the formation of t...
关键词：INFERTILITY SLC linking 
CCDC181 is required for sperm flagellum biogenesis and male fertility in mice
《Zoological Research》2024年第5期1061-1072,共12页Xiang-Jun Zhang Xiao-Ning Hou Jian-Teng Zhou Bao-Lu Shi Jing-Wei Ye Meng-Lei Yang Xiao-Hua Jiang Bo Xu Li-Min Wu Qing-Hua Shi 
supported by the National Natural Science Foundation of China(82071709,81971446,82171599,82374212);Global Select Project(DJK-LX-2022010)of the Institute of Health and Medicine,Hefei Comprehensive National Science Center;Joint Fund for New Medicine of USTC(YD9100002034)。
The structural integrity of the sperm flagellum is essential for proper sperm function.Flagellar defects can result in male infertility,yet the precise mechanisms underlying this relationship are not fully understood....
关键词：Male infertility CCDC181 MMAF SPERMIOGENESIS Flagellum biogenesis 
Homozygous CCDC146 mutation causes oligoasthenoteratozoospermia in humans and mice
《Zoological Research》2024年第5期1073-1087,共15页Jing-Wei Ye Tanveer Abbas Jian-Teng Zhou Jing Chen Meng-Lei Yang Xiong-Heng Huang Huan Zhang Hui Ma Ao Ma Bo Xu Ghulam Murtaza Qing-Hua Shi Bao-Lu Shi 
supported by the National Key Research and Developmental Program of China(2021YFC2700202,2022YFC2702601,2019YFA0802600,2022YFA0806303);National Natural Science Foundation of China(32470915,32000587,32270901,82171601);Global Select Project(DJK-LX-2022010)of the Institute of Health and Medicine,Hefei Comprehensive National Science Center,Joint Fund for New Medicine of USTC(YD9100002034);Scientific Research Foundation for Scholars of the First Affiliated Hospital of USTC(RC2023054)。
Infertility represents a significant health concern,with sperm quantity and quality being crucial determinants of male fertility.Oligoasthenoteratozoospermia(OAT)is characterized by reduced sperm motility,lower sperm ...
关键词：OLIGOASTHENOTERATOZOOSPERMIA Human infertility Sperm flagellum CCDC146 Intraflagellar transport IFT20 
CCDC189 affects sperm flagellum formation by interacting with CABCOC01被引量：1
《National Science Review》2023年第9期174-183,共10页Mengyue Wang Junyan Kang Zhiming Shen Yingchun Hu Min Chen Xiuhong Cui Hongbin Liu Fei Gao 
supported by the National Key R&D Program of China(2022YFC2702400);the National Natural Science Foun-dation of China(32270902,31970785 and 32170855);the Faculty Resources Project of the College of Life Sciences,Inner Mongolia University(2022-104).
Multiple morphological abnormalities of the sperm flagella(MMAF)are one of the major causes of male infertility and are characterized by multiple defects.In this study,we found that the coiled-coil domain-containing 1...
关键词：MMAF Ccdc189 Cabcoco1 flagellum formation radial spoke 
Study of the Climbing Behavior of the Flagella of Calamus Simplicifolius Based on Micro-CT and Nanoindentation
《Journal of Bionic Engineering》2022年第6期1790-1796,共7页Fukuan Dai Ziwei Wang Tuhua Zhong Hankun Wang Genlin Tian 
Basic Scientific Research Funds of the National Natural Science Foundation(Grant No.31800476);International Center for Bamboo and Rattan(Grant No.1632020011).
Rattan is a typical tropical climbing plant that uses flagella to climb supports to grow.A comprehensive understanding of the anatomic structure and micromechanics of rattan flagella might inspire more research on bio...
关键词：Calamus simplicifolius Micromechanical properties Structure FLAGELLUM BIOMATERIALS 
Novel biallelic loss-of-function mutations in CFAP43 cause multiple morphological abnormalities of the sperm flagellum in Pakistani families被引量：2
《Asian Journal of Andrology》2021年第6期627-632,共6页Ihsan Khan Basit Shah Sobia Dil Nadeem Ullah Jian-Teng Zhou Da-Ren Zhao Yuan-Wei Zhang Xiao-Hua Jiang Ranjha Khan Asad Khan Haider Ali Muhammad Zubair Wasim Shah Huan Zhang Qing-Hua Shi 
This work was supported by the National Natural Science Foundation of China(No.32070850);the National Natural Science Foundation of China(No.31630050,31890780,and 32061143006);the National Key Research and Developmental Program of China(2018YFC1003900,2019YFA0802600,and 2016YFC1000600);the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB19000000);the Fundamental Research Funds for the Central Universities(No.YD2070002006).
Multiple morphological abnormalities of the sperm flagella(MMAF)is a specific type of asthenoteratozoospermia,presenting with multiple morphological anomalies in spermatozoa,such as absent,bent,coiled,short,or irregul...
关键词：cilia and flagella-associated proteins male infertility multiple morphological abnormalities of the sperm flagella whole-exome sequencing 
Salmonella flagella confer anti-tumor immunological effect via activating Flagellin/TLR5 signalling within tumor microenvironment被引量：9
《Acta Pharmaceutica Sinica B》2021年第10期3165-3177,共13页Jianxiang Chen Yiting Qiao Guo Chen Cunjie Chang Heng Dong Bo Tang Xiawei Cheng Xiufeng Liu Zichun Hua 
supported by grants from the Jiangsu Provincial Nature Science Foundation(BK20192005,China);National Natural Science Foundation of China(81630092,81903143,81802338,and 82072646);Zhejiang Provincial Natural Science Foundation of China for Distinguished Young Scholars(LR21H160001);Start-up Grant of HZNU(4125C5021820470,China)。
Salmonella:mediated cancer therapy has achieved remarkable anti-tumor effects in experimental animal models,but the detailed mechanism remains unsolved.In this report,the active involvement of the host immune response...
关键词：Bacteria-mediated cancer therapy SALMONELLA VNP20009 FLAGELLUM FLAGELLIN TLR5 NF-kB Cancer immune therapy 
Experimental Verification for the Application Feasibility of Buckingham Pi Theorem in Designing a Scaled Model of Flagellated Swimmer with Traditional Resistive Force Theory
《Modern Mechanical Engineering》2021年第3期53-72,共20页Ouliang Jin 
The microstructure of bacterial is an important reference to design underwater swimmers. Applying Buckingham Pi Theorem is a possible method to build a scaled model based on a theore...
关键词：Micro AUV Bionic-Robot Flagellum Motor Low Reynolds Number 
Absence of murine CFAP61 causes male infertility due to multiple morphological abnormalities of the flagella被引量：1
《Science Bulletin》2020年第10期854-864,M0004,共12页Tao Huang Yingying Yin Chao Liu Mengjing Li Xiaochen Yu Xiuge Wang Haobo Zhang Tahir Muhammad Fei Gao Wei Li Zi-Jiang Chen Hongbin Liu Jinlong Ma 
We thank Zhang Jie for her assistance in confocal analysis(Advanced Medical Research Institute,Shandong University).This work was supported by the National Key Research and Development Programs of China(2018YFC1003400);the Young Scholars Program of Shandong University(2016WLJH50);the Natural Science Foundation of Shandong Province(ZR2017MH049).
Impaired flagellar development and impaired motility of sperm is a cause of infertility in males. Several genes, including those of the AKAP, CCDC, CFAP, and DNAH families, among others, are involved in the‘‘multipl...
关键词：Multiple morphological abnormalities of the flagella(MMAF) Male infertility Cfap61 Flagellum development 
RSBP15 interacts with and stabilizes dRSPH3 during sperm axoneme assembly in Drosophila
《Journal of Genetics and Genomics》2019年第6期281-290,共10页Ya Wang Rui Xu Yiwei Cheng Haowei Cao Zibin Wang Tianyu Zhu Jiayin Jiang Hao Zhang Chang Wang Lin Qi Mingxi Liu Xuejiang Guo Juan Huang Jiahao Sha 
supported by the National Basic Research Program of China (2016YFA0500903, 2016YFA0503300, and 2017YFA0103803);the National Natural Science Foundation of China (31530047 and 81771641);the Fok Ying Tung Education Foundation (161037);the 333 Project of Jiangsu Province (BRA2016386);the Program for Distinguished Talents of Six Domains in Jiangsu Province (YY-019)
Flagellum in sperm is composed of over 200 different proteins and is essential for sperm motility. In particular, defects in the assembly of the radial spoke in the flagellum result in male infertility due to loss of ...
关键词：RSBP15 RSPH3 FLAGELLUM Radial SPOKE DROSOPHILA 
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