GLOMERULOSCLEROSIS

作品数:33被引量:125H指数:6
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相关领域:医药卫生更多>>
相关作者:朱荃李海涛李晓冬更多>>
相关机构:南京中医药大学更多>>
相关期刊:《Chinese Medical Journal》《外科研究与新技术(中英文)》《Cellular & Molecular Immunology》《Journal of Diabetes Mellitus》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划更多>>
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CCN3 suppresses TGF-β1-induced extracellular matrix accumulation in human mesangial cells in vitro被引量:2
《Acta Pharmacologica Sinica》2018年第2期222-229,共8页Hai-fei LIU Hong LIU Lin-li LV Kun-ling MA Yi WEN Long CHEN Bi-cheng LIU 
This study was supported by grants from the National Natural Science Foundation of China (No 81300596), the Fifth Phase High-level Personnel Training Project of Jiangsu Provincial and the Jiangsu Provincial Special Program of Medical Science (No BK20161437).
Glomerular sclerosis is characterized by mesangial cell proliferation and progressive extracellular matrix (ECM) accumulation. CCN3 belongs to the CCN family of matrix proteins; increasing evidence suggests that CCN...
关键词:renal fibrosis GLOMERULOSCLEROSIS CCN3 FIBRONECTIN type I collagen MMPS 
The potential role of retinoic acid receptor on glomerulosclerosis in rats and podocytes injury is associated with the induction of MMP2 and MMP9被引量:3
《Acta Biochimica et Biophysica Sinica》2017年第8期669-679,共11页Xiuping Chen Yuanhan Qin Tianbiao Zhou Ling Jiang Fengying Lei He Qin Lei Zhang Zhiqiang Zhou 
Retinoic acid receptor α(RARe) plays a crucial role in kidney disease. However, the underlying mechanisms in glomerulosclerosis (GS) is still not clear. The roles of RARc( in an adriamycin (ADR)-induced GS ra...
关键词:retinoic acid receptor-alpha matrix metalloproteinase-2 matrix metalloproteinase-9 extracellular matrix glomerulo-sclerosis PODOCYTES all trans retinoic acid 
Ginkgo biloba extract suppresses hypertrophy and extracellular matrix accumulation in rat mesangial cells被引量:19
《Acta Pharmacologica Sinica》2006年第9期1222-1230,共9页Jian-yun WANG Xiao-xing YIN Yun-ming WU Dao-quan TANG Yuan-yuan GAO Mei-rong WAN Xiao-yu HOU Bei ZHANG 
Project supported by College Natural Science Research Foundation of Jiangsu Province(№03KJ13360143).
Aim: To observe the effects of Ginkgo biloba extract (EGb) on the hypertrophy of mesangial cells and the accumulation of extracellular matrix (ECM) in mesangial cells. Methods: Cultured mesangial cells were allo...
关键词:ginkgo biloba extract GLOMERULOSCLEROSIS oxidative stress TGF-β1 SMADS 
Effects of Shikonin on Proliferation, Apoptosis, and Extracellular Matrix of Human Mesangial Cells被引量:2
《Journal of Nanjing Medical University》2004年第6期304-307,共4页李海涛 李晓冬 朱荃 
SupportedbytheGrantofJiangsuprovincepost Ph .D .ScientificResearchGrant
Objective:To investigate the effect of shikonin on the proliferation, apoptosis and extracellular matrix (ECM) of human mesangial cells (MC). Methods: MC was cultured in vitro with different concentrations of glucose ...
关键词:SHIKONIN mesangial cell PROLIFERATION extracellular matrix APOPTOSIS GLOMERULOSCLEROSIS 
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