This study was supported by grants from the National Natural Science Foundation of China (No 81300596), the Fifth Phase High-level Personnel Training Project of Jiangsu Provincial and the Jiangsu Provincial Special Program of Medical Science (No BK20161437).
Glomerular sclerosis is characterized by mesangial cell proliferation and progressive extracellular matrix (ECM) accumulation. CCN3 belongs to the CCN family of matrix proteins; increasing evidence suggests that CCN...
Retinoic acid receptor α(RARe) plays a crucial role in kidney disease. However, the underlying mechanisms in glomerulosclerosis (GS) is still not clear. The roles of RARc( in an adriamycin (ADR)-induced GS ra...
Project supported by College Natural Science Research Foundation of Jiangsu Province(№03KJ13360143).
Aim: To observe the effects of Ginkgo biloba extract (EGb) on the hypertrophy of mesangial cells and the accumulation of extracellular matrix (ECM) in mesangial cells. Methods: Cultured mesangial cells were allo...
Objective:To investigate the effect of shikonin on the proliferation, apoptosis and extracellular matrix (ECM) of human mesangial cells (MC). Methods: MC was cultured in vitro with different concentrations of glucose ...