N-ACETYLGLUCOSAMINE

作品数：18被引量：21H指数：3
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相关领域：医药卫生生物学更多>>
相关作者：张晓刘龙更多>>
相关机构：武汉大学江南大学河南大学更多>>
相关期刊：《World Journal of Biological Chemistry》《Engineering》《Advances in Microbiology》《World Journal of Diabetes》更多>>
相关基金：国家自然科学基金高等学校学科创新引智计划国家重点基础研究发展计划更多>>
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O-linked β-N-acetylglucosamine transferase regulates macrophage polarization in diabetic periodontitis: In vivo and in vitro study
《World Journal of Diabetes》2025年第3期167-186,共20页Ye-Ke Wu Min Liu Hong-Ling Zhou Xiang He Jing Wei Wei-Han Hua Hui-Jing Li Qiang-Hua Yuan Yun-Fei Xie 
Supported by the National Natural Science Foundation of China,No.81973684;Natural Science Foundation of Sichuan Province,No.2023NSFSC1760;Youth Talent Fund of Sichuan Academy of Medical Sciences and Sichuan Provincial People’s Hospital,No.2021QN09。
BACKGROUND Periodontitis,when exacerbated by diabetes,is characterized by increased M1 macrophage polarization and decreased M2 polarization.O-linkedβ-N-acetylglucosamine(O-GlcNAcylation),catalyzed by O-GlcNAc transf...
关键词：Diabetic periodontitis Macrophage polarization O-linkedβ-N-acetylglucosamine O-linkedβ-N-acetylglucosamine transferase P38 
Antibodies Targeting a Conserved Surface Polysaccharide Are Protective Against a Wide Range of Microbial Pathogens Producing β-1-6-Linked Poly-N-Acetylglucosamine(PNAG)
《Engineering》2024年第7期69-76,共8页Xi Lu Guoqing Li Jing Pang Xinyi Yang Colette Cywes-Bentley Xuefu You Gerald B.Pier 
supported by the National Natural Science Foundation of China(32141003 and 81703399);the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(CIFMS,2021-I2M-1-026).
The b-1-6-linked poly-N-acetylglucosamine(PNAG)polymer is a conserved surface polysaccharide produced by many bacteria,fungi,and protozoan(and even filarial)parasites.This wide-ranging expression makes PNAG an attract...
关键词：Poly-N-acetylglucosamine Conjugate vaccine Monoclonal antibody 
Synthesis of 4-[F-18]Fluoro-4-Deoxy-N-Acetyl-1,3,6-Tri-O-Acetylglucosamine, a Potential Brain Imaging PET Agent
《Natural Science》2024年第3期19-23,共5页Murthy Akula Derek Cressy Lee Collier George Kabalka Dustin Osborne 
The synthesis of a promising brain imaging agent 4-[F-18]fluoro-4-deoxy-N-acetyl-1,3,6-tri-O-acetylglucosamine, 2, was successfully accomplished from commercially available N-acetyl glucosamine in 5 steps. The non-dec...
关键词：N-ACETYLGLUCOSAMINE AMYLOIDOGENESIS Lipase-Candida rugosa 
Production of N-acetylglucosamine with Vibrio alginolyticus FA2,an emerging platform for economical unsterile open fermentation
《Synthetic and Systems Biotechnology》2023年第3期546-554,共9页Yuan Peng Ping Xu Fei Tao 
the grant from National Natural Science Foundation of China(22138007 and 32170105).
Members of the Vibrionaceae family are predominantly fast-growing and halophilic microorganisms that have captured the attention of researchers owing to their potential applications in rapid biotechnology.Among them,V...
关键词：VIBRIO Open fermentation Metabolic engineering N-ACETYLGLUCOSAMINE 
Biosynthesis of Lacto-N-biose I from starch and N-acetylglucosamine via an in vitro synthetic enzymatic biosystem被引量：2
《Synthetic and Systems Biotechnology》2023年第3期555-562,共8页Lijie Chen Yanmei Qin Long Ma Dongdong Meng Chun You 
the National Key Research and Development Program of China(2021YFC2102300);the National Natural Science Foundation of China(Grant number 32022044);the cooperation fund with Shandong Runde Biotechnology Co.,LTD.
Human milk oligosaccharides(HMOs)are very distinctive components in human milk and are beneficial for infant health.Lacto-N-biose I(LNB)is the core structural unit of HMOs,which could be used for the synthesis of othe...
关键词：Human milk oligosaccharide In vitro synthetic enzymatic biosystem Lacto-N-biose I Thermostable enzyme 
Synergistic utilization of carbon sources for efficient biosynthesis of N-acetylglucosamine被引量：1
《Green Chemical Engineering》2023年第2期233-238,共6页Yanni Pei Yuhan Wang Xiaolin Shen Jia Wang Xinxiao Sun Qipeng Yuan 
supported by the National Key Research and Development Program of China(2018YFA0901800);the National Natural Science Foundation of China(21978015).
N-acetylglucosamine(GlcNAc)is an amino monosaccharide that has a variety of bioactivities and is widely used in pharmaceutical and food industries.Production of GlcNAc by chitin hydrolysis is limited by the supply of ...
关键词：N-ACETYLGLUCOSAMINE Synergistic carbon utilization Glucose facilitated diffusion system ACETATE 
Profiling the Bisecting N-acetylglucosamine Modification in Amniotic Membrane via Mass Spectrometry
《Genomics, Proteomics & Bioinformatics》2022年第4期648-656,共9页Qiushi Chen Yuanliang Zhang Keren Zhang Jie Liu Huozhen Pan Xinran Wang Siqi Li Dandan Hu Zhilong Lin Yun Zhao Guixue Hou Feng Guan Hong Li Siqi Liu Yan Ren 
supported by the National Natural Science Foundation of China(Grant No.31500670)。
Bisecting N-acetylglucosamine(GlcNAc),a GlcNAc linked to the coreβ-mannose residue via aβ1,4 linkage,is a special type of N-glycosylation that has been reported to be involved in various biological processes,such as...
关键词：GLYCAN GLYCOPROTEIN Amniotic membrane Bisecting N-acetylglucosamine Mass spectrometry 
Molecular dynamics simulations of the interaction between OH radicals in plasma with poly-β-1–6-N-acetylglucosamine被引量：4
《Plasma Science and Technology》2020年第12期59-69,共11页Shuhui YANG Tong ZHAO Jingxian CUI Zhiyun HAN Liang ZOU Xiaolong WANG Yuantao ZHANG 
supported by National Natural Science Foundation of China(Grant No.11675095);the Fundamental Research Funds of Shandong University(Grant No.2017JC017)。
Cold atmospheric plasma shows a satisfactory ability to inactivate bacterial biofilms that are difficult to remove using conventional methods in some cases. However, the researches on the inactivation mechanism are no...
关键词：cold atmospheric plasma molecular dynamics reactive oxygen species bacterial biofilm 
Metabolic engineering of Corynebacterium glutamicum S9114 based on whole-genome sequencing for efficient N-acetylglucosamine synthesis被引量：2
《Synthetic and Systems Biotechnology》2019年第3期120-129,共10页Chen Deng Xueqin Lv Yanfeng Liu Jianghua Li Wei Lu Guocheng Du Long Liu 
This work was financially supported by the National Natural Science Foundation of China(31622001,31671845,31600068);the Natural Science Foundation of Jiangsu Province(BK20160176);the 111 Project(111-2-06).
Glucosamine(GlcN)and its acetylated derivative N-acetylglucosamine(GlcNAc)are widely used in the pharmaceutical industries.Here,we attempted to achieve efficient production of GlcNAc via genomic engineering of Coryneb...
关键词：C.glutamicum Complete genome N-ACETYLGLUCOSAMINE Metabolic engineering 
Genetic polymorphism in Leishmania infantum isolates from human and animals determined by nagt PCR-RFLP
《Infectious Diseases of Poverty》2018年第1期523-530,共8页Adil El Hamouchi Sofia El Kacem Rajaa Ejghal Meryem Lemrani 
This publication is based on work supported by a grant(GTRX-14-60403-0)from the U.S.Civilian Research&Development Foundation(CRDF Global)with funding from the United States Department of State;The opinions,findings,and conclusions stated herein are those of the author(s)and do not necessarily reflect those of CRDF Global or the United States Department of State.
Background:Leishmania infantum is the causative agent of human visceral leishmaniasis(VL)and sporadic human cutaneous leishmaniasis(CL)in the Mediterranean region.The genetic variation of the Leishmania parasites may ...
关键词：Leishmania infantum Genetic variability N-acetylglucosamine-1-phosphate transferase PCR-RFLP Morocco 
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