Objective To explore the effects of anhedonia,childhood abuse,and depression on suicidal ideation,and the mediating role of anhedonia in adolescents.Methods A total of 7431 middle school students were invited to parti...
This study was supported by the National Natural Science Foundation of China(No.81630031);National Key Technology R&D Program(2015BAI13B01).
There is an increasing heavy disease burden of major depressive disorder(MDD)globally.Both high diagnostic heterogeneity and complicated pathological mechanisms of MDD pose significant challenges.There is much evidenc...
There is emerging evidence implicating glucagon-like peptide-1 (GLP-1) in reward, including palatable food reinforcement and alcohol-based reward circuitry. While recent findings suggest that mesolimbic structures, su...
BACKGROUND Obese patients(Ob)with a binge eating disorders(BED)behavior pattern have a higher prevalence of postprandial distress syndrome(PDS)compared to Ob without a BED behavior pattern,while an increase of PDS has...
Anhedonia, the presence of diminished pleasure or decreased motivation for rewards is considered one of the core symptoms of depression. Studies have shown that anhedonia and reduced reward learning predict a poor pro...
supported by the National Natural Science Foundation of China;the National Key Research and Development Program;the China Postdoctoral Science Foundation funded project;the Beijing Training Project for the Leading Talents in Science and Technology;the Beijing Municipal Science&Technology Commission Grant;the CAS key Laboratory of Mental Health,Institute of Psychology;the CAS/SAFEA International Partnership Program for Creative Research Teams
With the development of brain chemistry,we now hear more often the word"anhedonia".What is anhedonia?Psychiatrists define anhedonia as the inability to experience pleasure,to enjoy life.This term appeared in the mid 2...
Dr.Raymond C.K.Chan(陈楚侨)and his team at the Key Laboratory of Mental Health,Institute of Psychology,Chinese Academy of Sciences have recently employed a sophisticated behavioural paradigm to elucidate the nature an...
Anhedonia, the lowered ability to experience pleasure, is one of the non-motor symptoms in Parkinson’s disease. Recently, the distinction between consummatory and anticipatory anhedonia has been proposed and anhedoni...
Chronic exposure to hypobaric hypoxia (HH) causes memory impairment and prolonged state of mental confusion. However, effect of high altitude exposure on mood state and its underlying mechanisms have been poorly studi...
Anhedonia can be defined as a condition in which the hedonic capacity is totally or partially lost. From a psychobiological perspective, several researchers proposed that anhedonia has a putative neural substrate, the...