Objective:Addiction is a reward deficit and stress surfeit disorder.By using resting-state functional connectivity MRI(rs-fcMRI),the aim of this study is to investigate the pattern of aberrant brain networks in heroin...
Rationale:Heroin addiction is a disorder that stems from maladaptive plasticity within neural circuits and produces broad cognitive deficits.Despite considerable advances in psychotherapy and pharmacotherapy for heroi...
supported by the National Basic Research Program of China(2015CB553504);the National Natural Science Foundation of China(81471350 and 81671321);the Natural Science Foundation of Ningbo Municipality,Zhejiang Province,China(2015A610193)
Activation of presynaptic group II metabotropic glutamate receptors(mGluR2/3) inhibits drug reward and drug-seeking behavior, but the role of N-acetylaspartylglutamate(NAAG), an agonist of endogenous mGluR2/3,in h...
Acknowledgements This work was supported by the National Key Technology R&D Program in the 12th Five-Year Plan of China (No 2012BAI01B07) and the National Natural Science Foundation of China (No Ul132602 and 81171257), and was sponsored by the K C WONG Magna Fund at Ningbo University.
Aim: Glutamatergic neurotransmission in the nucleus accumbens (NAc) is crucial for the relapse to heroin seeking. The aim of this study was to determine whether mGluR5 in the NAc core or shell involved in heroin se...
This case report describes a case of ulcerative colitisthe onset of which occurred after the use of isotreti-noin for acne treatment. Our patient, a healthy maleyoung adult, after several months of isotretinoin use,de...
Aim: To investigate the different effects of heroin and milk in activating the corticostriatal system that plays a critical role in reward reinforcement learning. Methods: Male SD rats were trained daily for 15 d to...
Heroin addicts were treated with acupuncture, Chinese herbs, and acupuncture plus Chinese herbs respectively, their effects were compared with that of Western medicine. The scores of withdrawal symptoms were observed ...