ADDICTION

作品数：228被引量：201H指数：7
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相关领域：医药卫生更多>>
相关作者：胡莹赵艳刘贤宇王秋海张娟更多>>
相关机构：宁波大学宁波市第一医院睢宁县凌城中学河北昌黎第一中学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家科技支撑计划更多>>
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Drug-Seeking Behavior Is Significantly Attenuated in Nutritionally Supplemented Cocaine Withdrawn Sprague-Dawley Rats被引量：1
《Journal of Behavioral and Brain Science》2021年第7期143-156,共14页Lauriann Young Annice Webber-Waugh Karen Thaxter 
Aim: The effect of patented nutritional supplementation on drug-seeking behavior in cocaine addicted rats during acute drug withdrawal was investigated using a biased Conditioned Place Preference (CPP) paradigm...
关键词：COCAINE Conditioned Place Preference Nutritional Supplement ADDICTION Drug-Seeking Behavior 
Disruption of dopamine D1 receptor phosphorylation at serine 421 attenuates cocaine-induced behaviors in mice被引量：1
《Neuroscience Bulletin》2014年第6期1025-1035,共11页Ying Zhang Ning Wang Ping Su Jie Lu Yun Wang 
supported by grants from the National Natural Science Foundation of China (91332119,81161120497,30925015,30830044,31371143,30900582 and 81221002);the National Basic Research Development Program from the Ministry of Science and Technology of China (2014CB542204)
Dopamine D1 receptors（D1Rs） play a key role in cocaine addiction, and multiple protein kinases such as GRKs, PKA, and PKC are involved in their phosphorylation. Recently, we reported that protein kinase D1 phosphory...
关键词：protein kinase D1 dopamine D1 receptor PHOSPHORYLATION COCAINE ADDICTION conditioned place preference locomotor activity 
The role of K-opioid receptor activation in mediating antinociception and addiction被引量：8
《Acta Pharmacologica Sinica》2010年第9期1065-1070,共6页Yu-hua WANG Jian-feng SUN Yi-min TAO Zhi-qiang CHI Jing-gen LIU 
The K-opioid receptor （KOR）, a member of the opioid receptor family, is widely expressed in the central nervous system and peripheral tissues. Substantial evidence has shown that activation of KOR by agonists and en...
关键词：K-opioid receptor DYNORPHIN DESENSITIZATION ANTINOCICEPTION tolerance ADDICTION drug withdrawal cocaine reward nega-tive mood state 
Regulation of dopamine D3 receptors by protein-protein interactions
《Neuroscience Bulletin》2010年第2期163-167,共5页郭鸣雷 刘贤宇 毛利民 王强 
supported by the grant from the Saint Luke’s Hospital Foundation (Kansas City, MO, USA);grants (No. R01-DA010355, R01-MH061469) from the National Institutes of Health (Bethesda,MD, USA)
Gαi/o protein-coupled dopamine D3 receptors （D3Rs） are preferentially expressed in the limbic system, including the nucleus accumbens. This situates the receptor well in the regulation of limbic function and in the...
关键词：STRIATUM CAUDATE phosphorylation COCAINE ADDICTION cAMP CAMKII 
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