POTENTIATION

作品数：62被引量：152H指数：7
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相关领域：医药卫生更多>>
相关作者：韩太真赵欣赵士弟段雷胡文彬更多>>
相关机构：西安医科大学蚌埠医学院安徽中医药大学成都体育学院更多>>
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相关基金：国家自然科学基金高等学校学科创新引智计划安徽省自然科学基金北京市自然科学基金更多>>
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Potentiation of the lateral habenula-ventral tegmental area pathway underlines the susceptibility to depression in mice with chronic pain被引量：3
《Science China(Life Sciences)》2024年第1期67-82,共16页Chun-Kui Zhang Pan Wang Yuan-Yuan Ji Jian-Shuai Zhao Jun-Xiang Gu Xian-Xia Yan Hong-Wei Fan Ming-Ming Zhang Yu Qiao Xiao-Die Liu Bao-Juan Li Ming-Hui Wang Hai-Long Dong Hao-Hong Li Peng-Cheng Huang Yun-Qing Li Wu-Gang Hou Jin-Lian Li Tao Chen 
This work was supported by the National Natural Science Foundation of China(32192410,32071000,81870866,81571074,82230037,81971226,81620108008,82130034);the Foundation for Distinguished Young Scholars of ShaanXi(2019JC-21,2021JC-33);Young Scholar Project of the First Affiliated Hospital of Nanchang University(YFYPY202109);the Boost Plan of Xijing Hospital(XJZT21J01).
Chronic pain often develops severe mood changes such as depression.However,how chronic pain leads to depression remains elusive and the mechanisms determining individuals’responses to depression are largely unexplore...
关键词：chronic pain DEPRESSION lateral habenula ventral tegmental area DOPAMINE SUSCEPTIBILITY 
Evaluation of Disk Potentiation Test (DPT) and Double Disk Synergy Test (DDST) for The Detection of Metallo-β-Lactamases (MBLs) in Clinical Isolates of Bangladesh
《Advances in Infectious Diseases》2023年第4期609-626,共18页Sumon Kumar Das Afzal Sheikh Nikhat Ara Suma Mita Biswas Abhinandan Chowdhury Fatimah Az Zahra Chaman Ara Keya 
Objective: Increasing the emergence of Metallo-β-lactamase (MBL) producing gram-negative bacteria and their dexterous horizontal transmission demands rapid and accurate detection. This study was conducted to determin...
关键词：Disk Potentiation Test (DPT) Double Disk Synergy Test (DDST) Metallo-β-Lactamase (MBL) Sodium Mercaptoacetate (SMA) and Ethylenediaminetetraacetic Acid (EDTA) 
Potentiation of PIEZO2 mechanically-activated currents in sensory neurons mediates vincristine-induced mechanical hypersensitivity被引量：3
《Acta Pharmaceutica Sinica B》2023年第8期3365-3381,共17页Mingli Duan Yurui Jia Lifang Huo Yiting Gao Jia Wang Wei Zhang Zhanfeng Jia 
supported by NSFC grant 81571080(Zhanfeng Jia,China),81872848(Wei Zhang,China);the Central Government Guiding Local Funding Project for Scientific and Technological Development 206Z7703G(Zhanfeng Jia,China);Key Project and Cultivation Project of Precision Medicine Joint Fund of Natural Science Foundation of Hebei Province H2021206406(Zhanfeng Jia,China),H2022206211(Wei Zhang,China)and H2020206165(Zhanfeng Jia,China);Science and Technology Project of Hebei Education Department ZD2020107(Zhanfeng Jia,China);Science Fund for Creative Research Groups of Natural Science Foundation of Hebei Province H2020206474,China.
Vincristine,a widely used chemotherapeutic agent for treating different cancer,often induces severe peripheral neuropathic pain.A common symptom of vincristine-induced peripheral neuropathic pain is mechanical allodyn...
关键词：VINCRISTINE Peripheral neuropathic pain Mechanical hypersensitivity Dorsal root ganglion neurons PIEZO2mechanically-activated currents 
Pathologically triggered in situ aggregation of nanoparticles for inflammation-targeting amplification and therapeutic potentiation被引量：3
《Acta Pharmaceutica Sinica B》2023年第1期390-409,共20页Qiang Nie Chenwen Li Yu Wang Yi Hu Wendan Pu Qixiong Zhang Jiajun Cai Yongyao Lin Gang Li Chenping Wang Lanlan Li Yin Dou Jianxiang Zhang 
supported by the National Natural Science Foundation of China(No.81971727);the Program for Postdoctoral Innovative Talent of Chongqing(China);the Program for Scientific and Technological Innovation Leader of Chongqing(No.CQYC20210302362,China);the Program for Distinguished Young Scholars of TMMU(China)。
Uncontrolled and persistent inflammation is closely related to numerous acute and chronic diseases.However,effective targeting delivery systems remain to be developed for precision therapy of inflammatory diseases.Her...
关键词：Inflammatory disease Reactive oxygen species MYELOPEROXIDASE Targeted therapy NANOPARTICLES Surface engineering Triggerable aggregation Nanotherapy 
NMDAR-dependent somatic potentiation of synaptic inputs is correlated withβamyloid-mediated neuronal hyperactivity
《Translational Neurodegeneration》2021年第3期432-446,共15页Yifei Bao Xin Yang Yi Fu Zhengyan Li Ru Gong Wei Lu 
This work was supported by grants to W.L.from the National Natural Science Foundation of China(31730107,31970959,31671056).
Background:βAmyloid(Aβ)-mediated neuronal hyperactivity,a key feature of the early stage of Alzheimer’s disease(AD),is recently proposed to be initiated by the suppression of glutamate reuptake.Nevertheless,the und...
关键词：NMDA receptor HYPERACTIVITY Somatic modifcation Alzheimer’s disease 
Short-Term Visual Experience Leads to Potentiation of Spontaneous Activity in Mouse Superior Colliculus
《Neuroscience Bulletin》2021年第3期353-368,共16页Qingpeng Yu Hang Fu Gang Wang Jiayi Zhang Biao Yan 
supported by the National Natural Science Foundation of China(31771195,81790640 and 82021002);a Shanghai Municipal Science and Technology Major Project(2018SHZDZX01);ZJLab,Key Scientific Technological Innovation Research Project of the Ministry of Education,Sanming Project of Medicine in Shenzhen(SZSM202011015);Shanghai Health and Family Planning Commission(20164Y0096,20184Y0184)。
Spontaneous activity in the brain maintains an internal structured pattern that reflects the external environment,which is essential for processing information and developing perception and cognition.An essential prer...
关键词：Spontaneous activity Visual experience POTENTIATION Superior colliculus Feature selectivity Glutamate homeostasis 
Potentiation of NETs release is novel characteristic of TREM-1 activation and the pharmacological inhibition of TREM-1 could prevent from the deleterious consequences of NETs release in sepsis被引量：18
《Cellular & Molecular Immunology》2021年第2期452-460,共9页Amir Boufenzer Kevin Carrasco Lucie Jolly Benjamin Brustolin Elisa Di-Pillo Marc Derive Sébastien Gibot 
During sepsis,neutrophil activation induces endothelial cell(EC)dysfunction partly through neutrophil extracellular trap(NET)release.The triggering receptor expressed on myeloid cell-1(TREM-1)is an orphan immune recep...
关键词：TREM-1 NETS SEPSIS endothelial cell activation vascular dysfunction LR12 
Activated PKB/GSK-3β synergizes with PKC-δ signaling in attenuating myocardial ischemia/reperfusion injury via potentiation of NRF2 activity: Therapeutic efficacy of dihydrotanshinone-Ⅰ被引量：12
《Acta Pharmaceutica Sinica B》2021年第1期71-88,共18页Hao Zengy Lingling Wangy Jiawei Zhang Ting Pan Yinghua Yu Jingxia Lu Ping Zhou Hua Yang Ping Li 
supported by the National Key R&D Program of China(No.2019YFC1711000);National Natural Science Foundation of China(81421005 and 81722048);111 Project(B16046,China);“Double First-Class”University Project(CPU2018GF04,China);the Qing Lan Project of Jiangsu Province(China)
Disrupted redox status primarily contributes to myocardial ischemia/reperfusion injury(MIRI).NRF2,the endogenous antioxidant regulator,might provide therapeutic benefits.Dihydrotanshinone-Ⅰ(DT)is an active component ...
关键词：DihydrotanshinoneⅠ NRF2 Cytoplasmic/nuclear translocation PKC-δ PKB/GSK-3β/Fyn Phosphorylation Redox homeostasis Ischemia/reperfusion injury 
Paired associative stimulation improves synaptic plasticity and functional outcomes after cerebral ischemia被引量：6
《Neural Regeneration Research》2019年第11期1968-1976,共9页Yan Hu Tie-Cheng Guo Xiang-Yu Zhang Jun Tian Yin-Shan Lu 
supported by the National Natural Science Foundation of China,No.81272156(to TCG)
Paired associative stimulation is a relatively new non-invasive brain stimulation technique that combines transcranial magnetic stimulation and peripheral nerve stimulation. The effects of paired associative stimulati...
关键词：cerebral ischemia paired associative stimulation cognitive function long-term POTENTIATION SYNAPTIC plasticity MORRIS water maze SYNAPTIC structure N-methyl-D-aspartic acid receptor BRAIN-DERIVED NEUROTROPHIC factor MULTI-ELECTRODE array neural regeneration 
Microbiostatic, antioxidative and cytotoxic potentiation of some grasses of Bahawalpur, Pakistan被引量：1
《Journal of Traditional Chinese Medicine》2019年第4期482-491,共10页Iram Fatima Sobia Kanwal Tariq Mahmood 
OBJECTIVE: To evaluate biological potential of methanol and n-hexane extracts of aerial parts in seven species of family Poaceae.METHODS: Qualitative phytochemical tests were done by using standard protocols. In vitro...
关键词：POACEAE Methanol N-HEXANE ANTI-INFECTIVE agents Antioxidants CYTOTOXINS 
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