VINCRISTINE

作品数：55被引量：119H指数：6
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相关领域：医药卫生更多>>
相关作者：黄岚峰刘国卿刘晓东张强李婷更多>>
相关机构：深圳市龙华新区人民医院吉林大学第二医院深圳市人民医院中国药科大学更多>>
相关期刊：《Science Bulletin》《China Medical Abstracts(Internal Medicine)》《Journal of Chinese Pharmaceutical Sciences》《世界核心医学期刊文摘（神经病学分册）》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划深圳市宝安区科技计划项目国家教育部博士点基金更多>>
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构建重定向的NF-κB/OIP5表达程序以增强化疗对膀胱癌的治疗效果
《Science Bulletin》2023年第24期3207-3224,M0006,共19页郑彬彬 牛立慢 徐海波 杨育宾 陈延萍 王晨光 陈巍 黄卫人 
supported by the National Key R&D Program of China(2019YFA0906003);the National Natural Science Foundation of China(32000989);China Postdoctoral Science Foundation Grant(2020M682911 and 2020M670051ZX);Guangdong Special Support Program(2021JC06Y578);the Shenzhen Municipal Government of China(JCYJ20200109120016553,CJGJZD20200617102403009,and RCBS20210706092256081);the Sanming Project of Shenzhen Health and Family Planning Commission(SZSM202011017);Shenzhen Institute of Synthetic Biology Scientific Research Program(ZTXM20214005);the Shenzhen High-level Hospital Construction Fund。
NF-κB是重要的转录调控因子,对下游肿瘤耐药基因起关键调控作用.基于CRISPR基因编辑技术,可在膀胱癌中构建人工合成的基因表达程序,以重编程肿瘤药物应答过程.本研究发现Opa相互作用蛋白5(OIP5)在NF-κB激活后上调,并引起膀胱癌对长春...
关键词：Drug resistance Gene circuit RNA engineering NF-jB OIP5 VINCRISTINE 
Potentiation of PIEZO2 mechanically-activated currents in sensory neurons mediates vincristine-induced mechanical hypersensitivity被引量：3
《Acta Pharmaceutica Sinica B》2023年第8期3365-3381,共17页Mingli Duan Yurui Jia Lifang Huo Yiting Gao Jia Wang Wei Zhang Zhanfeng Jia 
supported by NSFC grant 81571080(Zhanfeng Jia,China),81872848(Wei Zhang,China);the Central Government Guiding Local Funding Project for Scientific and Technological Development 206Z7703G(Zhanfeng Jia,China);Key Project and Cultivation Project of Precision Medicine Joint Fund of Natural Science Foundation of Hebei Province H2021206406(Zhanfeng Jia,China),H2022206211(Wei Zhang,China)and H2020206165(Zhanfeng Jia,China);Science and Technology Project of Hebei Education Department ZD2020107(Zhanfeng Jia,China);Science Fund for Creative Research Groups of Natural Science Foundation of Hebei Province H2020206474,China.
Vincristine,a widely used chemotherapeutic agent for treating different cancer,often induces severe peripheral neuropathic pain.A common symptom of vincristine-induced peripheral neuropathic pain is mechanical allodyn...
关键词：VINCRISTINE Peripheral neuropathic pain Mechanical hypersensitivity Dorsal root ganglion neurons PIEZO2mechanically-activated currents 
Unilateral Ptosis in a Child with Wilm’s Tumor Induced by Vincristine
《Journal of Cancer Therapy》2022年第12期649-653,共5页Aziza El Ouali Karim Lahrache Zohair El Haddar Ayad Ghannam Abdeladim Babakhouya Maria Rkain Noufissa Benajiba 
Vincristine is a chemotherapy drug belonging to the group of Vinca alkaloids which also includes vinblastine and vindesine. It is used in hematological malignancies and solid tumors. The Vinca alkaloids are neurotoxic...
关键词：Wilms’ Tumor VINCRISTINE NEUROPATHY PTOSIS 
Dehydroabietic acid chemosensitizes drug-resistant acute lymphoblastic leukemia cells by downregulating survivin expression被引量：1
《Asian Pacific Journal of Tropical Biomedicine》2022年第9期383-390,共8页Li-Li Shen Wei-Hua Huang Hui-Jun Zhao Xue-Wei Yuan 
supported by Suzhou Science and Technology Development Plan (SKJYD2021047);the Fundation of Suzhou Kowloon Hospital (SZJL202111 and SZJL202104)
Objective:To explore the mechanism of drug resistance in acute lymphoblastic leukemia and the anti-tumor effect of combination therapy of dehydroabietic acid and vincristine against acute lymphoblastic leukemia cells....
关键词：Acute lymphoblastic leukemia Drug resistance SURVIVIN Dehydroabietic acid REH cells VINCRISTINE 
Correction to “Folic acid-conjugated liposomal vincristine for multidrug resistant cancer therapy”
《Asian Journal of Pharmaceutical Sciences》2022年第4期610-611,共2页Chenyu Wang Linglin Feng Xiangkun Yang FeiWang Weiyue Lu 
In the original version of this article on p 122, two inappropriate images were placed in B and C of Fig. 1, which didn’t represent the group of FA-PEG-LS and PEG-LS/VCR. In the revised graphic provided below, the ap...
关键词：CORRECTION revised CANCER 
Gray zone lymphoma effectively treated with cyclophosphamide,doxorubicin,vincristine,prednisolone,and rituximab chemotherapy:A case report
《World Journal of Clinical Cases》2022年第17期5708-5716,共9页Nobumasa Hojo Makoto Nagasaki Yasuha Mihara 
BACKGROUND B-cell lymphoma,unclassifiable,with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma(BCLu-DLBCL/cHL),also referred to as gray zone lymphoma(GZL),is known to share f...
关键词：Classical Hodgkin lymphoma Diffuse large B-cell lymphoma Gray zone lymphoma Programmed cell death protein ligand 1 R-CHOP Case report 
Research Progress of Natural Antitumor Drugs
《外文科技期刊数据库(文摘版)医药卫生》2022年第6期176-182,共7页BIANJiayi 
The means of cancer treatment and the understanding of chemotherapeutic drugs have made continuous progress in the past few decades. Chemotherapy is a basic and widely useful therapeutic method, and various therapeuti...
关键词：vincristine alkaloids TAXANE CAMPTOTHECIN anti-cancer mechanism 
Chidamide combined with cyclophosphamide,doxorubicin,vincristine and prednisone in previously untreated patients with peripheral T-cell lymphoma被引量：5
《Chinese Journal of Cancer Research》2021年第5期616-626,共11页Lin Gui Junning Cao Dongmei Ji Huilai Zhang Qian Fan Jun Zhu Yuqin Song Shiyu Jiang Zhiqiang Ning Jia Yu Yuankai Shi 
supported by the sponsor Shenzhen Chipscreen Biosciences Co.,LTD.;by grants from the China National Major Project for New Drug Innovation(No.2017ZX09304015);the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(CIFMS)(No.2016-I2M-1-001)。
Objective:Chidamide is an oral histone deacetylase subtype-selective inhibitor approved for relapsed or refractory peripheral T-cell lymphoma(PTCL).This phase 1 b study evaluated the safety,pharmacokinetics,and prelim...
关键词：CHIDAMIDE CHOP PTCL frontline treatment 
Primary gastric non-Hodgkin lymphomas:Recent advances regarding disease pathogenesis and treatment被引量：8
《World Journal of Gastroenterology》2021年第35期5932-5945,共14页Michael D Diamantidis Maria Papaioannou Evdoxia Hatjiharissi 
Primary gastric lymphomas(PGLs)are distinct lymphoproliferative neoplasms described as heterogeneous entities clinically and molecularly.Their main histological types are diffuse large B-cell lymphoma(DLBCL)or mucosaa...
关键词：Primary gastric lymphoma Extranodal non-Hodgkin’s lymphoma Diffuse large B-cell lymphoma Mucosa-associated lymphoid tissue IMMUNOCHEMOTHERAPY Rituximab-cyclophosphamide doxorubicin vincristine prednisone 
Successful treatment of a high-risk nonseminomatous germ cell tumor using etoposide, methotrexate, actinomycin D, cyclophosphamide, and vincristine: A case report
《World Journal of Clinical Cases》2020年第21期5334-5340,共7页Jina Yun Sang W Lee Sung H Lim Se H Kim Chan K Kim Seong K Park 
Supported by the Soonchunhyang University Research Fund,No.20200011.
BACKGROUND Choriocarcinoma is an infrequent entity and the most aggressive subtype of germcell tumors.Because of early metastatic spread and rapid disease progression,choriocarcinoma patients display poor prognosis.Al...
关键词：Antineoplastic combined chemotherapy protocols CHORIOCARCINOMA Testicular neoplasms CYCLOPHOSPHAMIDE METHOTREXATE Case report 
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