云南高校图书馆联盟文献共享服务平台- TAXANE

TAXANE: 作品数：46被引量：75H指数：5; 导出分析报告; 相关领域：医药卫生农业科学更多>>; 相关作者：杨蓉傅宏征蔡田芝谢可辉更多>>; 相关机构：北京大学佛罗里达州立大学北京协和医学院江苏省肿瘤医院更多>>; 相关期刊：《Discussion of Clinical Cases》《Journal of Pharmaceutical Analysis》《Asian Journal of Andrology》《Medical Review》更多>>; 相关基金：国家自然科学基金更多>>

Cancer nuclear envelope rupture and repair in taxane resistance: 《Medical Review》2024年第6期522-530,共9页Ana P.Xu Lucy B.Xu Elizabeth R.Smith Joshua S.Fleishman Zhe-Sheng Chen Xiang-Xi Xu; partially supported by NIH funding R01 CA095071,CA79716,and CA75389 to XX from NCI,NIH;seed funding from Sylvester Comprehensive Cancer Center,University of Miami.; Taxanes,including paclitaxel,docetaxel,and cabazitaxel,are key agents in cancer treatment,often used as frontline chemotherapy drugs in combination with other agent(s)(commonly carboplatin)and as second-line treatment...; 关键词：chemotherapy drug resistance TAXANES PACLITAXEL MICROTUBULES nuclear envelope

Identification of missing CYP450 enzymes involved in paclitaxel biosynthesis and heterologous reconstitution of baccatin III: 《Chinese Journal of Natural Medicines》2024年第4期291-292,共2页DU Jinfa LIAO Pan LU Xu; Paclitaxel,a tetracyclic diterpenoid,has garnered attention for its potent anti-cancer properties and intricate molecular structure,making it a significant target for chemical synthesis and biosynthesis[1].However,its...; 关键词：Paclitaxel biosynthesis Baccatin III Cytochrome P450 Taxane oxetanase 1 Heterologous reconstitution

Acquisition of taxane resistance by p53 inactivation in ovarian cancer cells被引量：3: 《Acta Pharmacologica Sinica》2022年第9期2419-2428,共10页Changfa Shu Xi Zheng Alafate Wuhafu Danielle Cicka Sean Doyle Qiankun Niu Dacheng Fan Kun Qian Andrey AIvanov Yuhong Du Xiulei Mo Haian Fu; This work was supported by the Georgia Research Alliance(Distinguished Investigator award to HF);the NCI Emory Lung Cancer SPORE Career Enhancement Program(P50CA217691 to XM);the Imagine,Innovate and Impact(I3)Funds from the Emory School of Medicine;and through the Georgia CTSA NIH award(UL1-TR002378)and Winship Cancer Institute(NIH 5P30CA138292).; Ovarian cancer is one of the most common gynecologic malignancies in women and has a poor prognosis.Taxanes are a class of standard first-line chemotherapeutic agents for the treatment of ovarian cancer.However,tumor-...; 关键词：PACLITAXEL DOCETAXEL Ovarian cancer TP53 ACSM3 WNT signaling

Adenosine triphosphate-based tumor chemosensitivity assay may predict the clinical outcomes of gastric cancer patients receiving taxane-based post-operative adjuvant chemotherapy被引量：1: 《Chinese Medical Journal》2022年第11期1383-1385,共3页Yicong Bian Minzhou Huang Sheng Ma Linsheng Liu Fan Xia Zhiyao Chen Di Yu Chenrong Huang Liyan Miao; National Key New Drug Creation Special Programs(No. 2017ZX09304-021);Science and Technology Plan of Suzhou(No. SYSD2017151); To the Editor:Gastric cancer is one of the most commonly diagnosed cancers in the world.For patients with a pathological tumor-node-metastasis stage of II or III,postoperative adjuvant chemotherapy is generally requir...; 关键词：clinical CHEMOTHERAPY patients

Research Progress of Natural Antitumor Drugs: 《外文科技期刊数据库(文摘版)医药卫生》2022年第6期176-182,共7页BIANJiayi; The means of cancer treatment and the understanding of chemotherapeutic drugs have made continuous progress in the past few decades. Chemotherapy is a basic and widely useful therapeutic method, and various therapeuti...; 关键词：vincristine alkaloids TAXANE CAMPTOTHECIN anti-cancer mechanism

Assessing taxane-associated adverse events using the FDA adverse event reporting system database被引量：5: 《Chinese Medical Journal》2021年第12期1471-1476,共6页Dong-Hui Lao Ye Chen Jun Fan Jian-Zhong Zhang; Background:Taxanes are an essential class of antineoplastic agents used to treat various cancers and are a fundamental cause of hypersensitivity reactions.In addition,other adverse events,such as bone marrow toxicity ...; 关键词：TAXANE PHARMACOVIGILANCE Bone marrow toxicity Peripheral neuropathy

Quantitative analysis of taxane drug target engagement of microtubules in circulating tumor cells from metastatic castration resistant prostate cancer patients treated with CRXL301,a nanoparticle of docetaxel: 《Cancer Drug Resistance》2020年第3期636-646,共11页Eiman Mukhtar Daniel Worroll Giuseppe Galletti Shelly Schuster Sarina A.Piha-Paul Paraskevi Giannakakou; Aim:We reviewed the radiographic response of three patients with metastatic castration-resistant prostate cancer treated with CRXL301,a docetaxel nanoparticle.For these three patients,we isolated and analyzed circulat...; 关键词：Liquid biopsy circulating tumor cells castration-resistant prostate cancer MICROTUBULES TAXANES biomarkers

Methylated PLK2 is a prognostic biomarker in taxane-treated breast cancers: 《Discussion of Clinical Cases》2020年第2期7-12,共6页Priti Chivers Laura Lattanzio Ornella Garrone Daniela Vivenza Nel Syed Marco C.Merlano Tim Crook Helen M.Coley Cristiana Lo Nigro; funding from Breast Cancer Campaign UK for a grant to support this work(HMC).; Background:In search of potential biomarkers of drug responsiveness the tumour suppressor PLK2 has been identified as a mediator of taxane sensitivity in some tumour types,based on its role of G2M checkpoint regulatio...; 关键词：Breast cancer PLK2 DNA methylation Drug resistance TAXANES

Impact of taxanes on androgen receptor signaling被引量：1: 《Asian Journal of Andrology》2019年第3期249-252,共4页Shanshan Bai Bryan Y Zhang Yan Dong; the following grants: National Institutes ofHealth/National Cancer Institute (NIH/NCI) RO1 CAI88609, Department of Defense W81XWH-15-1-0439, W81XWH-16-1-0317, and W81XWH-14-1-0485;National Natural Science Foundation of China Project 81430087.; The development and progression of metastatic castration-resistant prostate cancer is the major challenge in the treatment of advanced prostate cancer. The androgen receptor signaling pathway remains active in metasta...; 关键词：ANDROGEN RECEPTOR ANDROGEN RECEPTOR splice variant CABAZITAXEL DOCETAXEL prostate cancer TAXANE

Current taxane formulations and emerging cabazitaxel delivery systems被引量：5: 《Nano Research》2018年第10期5193-5218,共26页Boyang Sun Robert M. Straubinger Jonathan F. Lovell; Cabazitaxel is a second-generation taxane with promising anti-tumor activity and is approved for treating hormone-refractory metastatic prostate cancer previously treated with docetaxel. Although first-generation taxa...; 关键词：CABAZITAXEL Jevtana TAXANES drug delivery systems NANOCARRIERS

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