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作品数：79被引量：139H指数：6
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相关作者：曾晞牟兰徐光军冉霞更多>>
相关机构：河北工程大学郑州大学贵州省大环化学及超分子化学重点实验室更多>>
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Trivalent SARS-CoV-2 virus-like particle vaccines exhibit broad-spectrum neutralization and protection against XBB.1 and BA.2.86 variants
《Virologica Sinica》2024年第5期836-839,共4页Lu Zhang Siyu Tian Jun Dai Yuanyuan Li Yu Zhou Yan Li Jiao Xu Shuyun Liu Zhiwei Lin Zhaoyong Zhang Jiantao Chen Peilan Wei Jingxian Zhao Jing Jin Yanqun Wang Jincun Zhao 
supported by a grant from the National Key R&D Program of China(2023YFC3041600 YW,the National Natural Science Foundation of China(82025001 JZ,92369113 YW,82172240 YW);Guangdong Basic and Applied Research Projects(2023B1515020040 YW,2021B1515130005 JZ,2021B1212030016 JD,2021A1111100009 JD);Science and Technology Planning Project of Guangzhou City(2023A04J1279 LZ);ZhongNanShan Medical Foundation of Guangdong Province(ZNSA-2020013 JZ);the Science and Technology Project of General Administration of Customs,P.R.China(2023HK065 LZ);State Key Laboratory of Respiratory Disease(SKLRD-Z-202214,SKLRD-OP-202309 YW,SKLRD-Z-202411 LZ);the Self-supporting Program of Guangzhou Laboratory(GZNL2023A01006,SRPG22-001);Guangzhou Medical University(YP2022005 YW);Korea Institute of Planning and Evaluation for Technology in Food,Agriculture and Forestry(IPET)through Animal Disease Management Technology Advancement Support Program,funded by the Ministry of Agriculture,Food and Rural Affairs(MAFRA)(122012-2,122060-2 JZ);the National Clinical Research Center for Respiratory Disease(BRD-NCRCRD,Guangzhou,Southern China).Patronus Biotech is a company researching virus-like particle display technology and vaccines.Yu Zhou and Jing Jin are named inventors on a patent invention relating to the described novel SARS-CoV-2 virus-like particle vaccine.All BALB/c mouse experiments complied with relevant ethical regulations for animal research and were approved by the LUYE PHARMA Animal Experimentation Ethics Committee.The K18-hACE2 mouse experiment was reviewed and approved by the Institutional Animal Care and Use Committees of Guangzhou Medical University(2023-0451).All authors declare that they have no conflict of interests.
Dear Editor,The newly emerged severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)Omicron subvariants(XBB.1,EG.5 and JN.1)and sublineages have been circulating globally with superior growth advantages over othe...
关键词：VACCINE vaccines acute 
Highly active organocatalyst from a trivalent phosphazenium salt for ring-opening copolymerization of epoxides and cyclic anhydrides enhanced by hydrogen bonding interactions
《Science China Chemistry》2024年第9期3111-3120,共10页Chunhuan Jiang Junqi Wang Xiaoyu Liu Xiaoxia You Ronglin Zhong Chuanli Ren Zhibo Li 
supported by the National Key R&D Program of China(2021YFA1501600);National Natural Science Foundation of China(22031005)。
It is highly desirable to develop simple organocatalysts for the controlled ring-opening alternating copolymerization(ROAC)of epoxides and cyclic anhydrides,leading to high molecular weight polyesters.Hence,a phosphaz...
关键词：ring-opening copolymerization ORGANOCATALYST EPOXIDES cyclic anhydrides phosphazenium salt 
Robust neutralizing antibody response to the XBB.1.5 trivalent recombinant protein vaccine booster
《Signal Transduction and Targeted Therapy》2024年第9期3560-3562,共3页Bing-Dong Zhan Xue-Dong Song Xin Yu Guo-Jian Yang Sheng Wan Mai-Juan Ma 
supported by grants from the National Natural Science Foundation of China(82273692 and 92169207);the Quzhou Science and Technology Bureau(2021K12)。
Dear Editor,The global prevalence of XBB subvariants,known for their significant immune evasion,has driven the development and adaptation of XBB vaccines.Monovalent XBB.1.5 mRNA vaccines have been developed and shown ...
关键词：valent NEUTRAL BREAKTHROUGH 
Robust neutralization of SARS-CoV-2 variants including JN.1 and BA.2.87.1 by trivalent XBB vaccine-induced antibodies被引量：2
《Signal Transduction and Targeted Therapy》2024年第6期2359-2361,共3页Xun Wang Shujun Jiang Wentai Ma Yanliang Zhang Pengfei Wang 
supported by funding from the National Natural Science Foundation of China(32270142 to P.W.);the Shanghai Rising-Star Program(22QA1408800 to P.W.);the Program of Science and Technology Cooperation with Hong Kong region,Macao region,and Taiwan region(23410760500 to P.W.);Nanjing Research Center for Infectious Diseases of Integrated Traditional Chinese and Western Medicine(YBZX2022 to Y.Z.);NATCM’s Project of High-level Construction of Key TCM Disciplines;support from AI for Science project of Fudan University(XM06231724);Open Research Fund of State Key Laboratory of Genetic Engineering,Fudan University(No.SKLGE-2304);Xiaomi Young Talents Program.
Dear Editor,The rapid and widespread transmission of SARS-CoV-2 has led to the emergence of multiple variants of concern(VOCs),most notably the Omicron variant,which continues to evolve and diversify into a range of s...
关键词：evolve NEUTRALIZATION VARIANTS 
Introducing oxygen vacancies in TiO_(2) lattice through trivalent iron to enhance the photocatalytic removal of indoor NO被引量：3
《International Journal of Minerals,Metallurgy and Materials》2023年第10期2025-2035,共11页Peng Sun Sumei Han Jinhua Liu Jingjing Zhang Shuo Yang Faguo Wang Wenxiu Liu Shu Yin Zhanwu Ning Wenbin Cao 
supported by the BJAST High-level Innovation Team Program (No.BGS202001);the Beijing Postdoctoral Research Foundation (No.2022-ZZ-046);the National Natural and Science Foundation of China (No.51972026);the Japan Society for the Promotion of Science (JSPS)Grant-in-Aid for the Scientific Research (KAKENHI,Nos.16H06439 and 20H00297);the Dynamic Alliance for Open Innovations Bridging Human,Environment and Materials,the Cooperative Research Program of“Network Joint Research Center for Materials and Devices.”;the scholarship granted to a visiting Ph.D.student of the Inter-University Exchange Project by the China Scholarship Council (CSC,No.201906460113)。
The synthesis of oxygen vacancies(OVs)-modified TiO_(2)under mild conditions is attractive.In this work,OVs were easily introduced in TiO_(2)lattice during the hydrothermal doping process of trivalent iron ions.Theore...
关键词：oxygen vacancies density functional theory calculations iron-doped titanium dioxide carrier separation photocatalytic removal of indoor nitric oxide 
LDH-based nanomaterials for photocatalytic applications:A comprehensive review on the role of bi/trivalent cations, anions,morphology, defect engineering, memory effect, and heterojunction formation被引量：1
《Journal of Energy Chemistry》2023年第9期242-276,共35页Azmat Ali Khan Muhammad Tahir Nazish Khan 
United Arab Emirates University (UAE) for providing funding of this research undergrant # 12N097。
Using sunlight to drive chemical reactions via photocatalysis is paramount for a sustainable future.Among several photocatalysts,employing layered double hydrides(LDH) for photocatalytic application is most straightfo...
关键词：LDH Properties Potential photocatalyst Photocatalytic application Photocatalytic properties Improvement strategies 
Full-profile pharmacokinetics, anticancer activity and toxicity of an extended release trivalent PEGylated irinotecan prodrug被引量：1
《Acta Pharmaceutica Sinica B》2023年第8期3444-3453,共10页Shiwen Song Dong Sun Hong Wang Jinliang Wang Huijing Yan Xuan Zhao John Paul Fawcett Xin Xu Deqi Cai Jingkai Gu 
supported by the National Natural Science Foundation of China(Grant Nos.82030107 and 81872831);the National Science and Technology Major Projects for significant new drugs creation of the 13th five-year plan(2017ZX09101001 and 2018ZX09721002007,China)。
Irinotecan is an anticancer topoisomerase I inhibitor that acts as a prodrug of the active metabolite,SN-38.Unfortunately,the limited utility of irinotecan is attributed to its pH-dependent stability,short half-life a...
关键词：IRINOTECAN SN-38 Trivalent PEGylated irinotecan PRODRUG Full-profile pharmacokinetics 
Conformational Behavior of Single Circular Semiflexible Polyelectrolyte in the Presence of Multivalent Counterions
《Chinese Journal of Polymer Science》2023年第3期448-458,I0010,共12页Zhi-Yong Yang Wen-Long Lin Ai-Hua Chai Dan Lu Nian-Qian Kang Lin-Xi Zhang 
financially supported by the National Natural Science Foundation of China (Nos. 21863003, 22173080, 21873082, 21674096 and 61762048);the Jiangxi Provincial Natural Science Foundation (No.20202BABL203015)。
Langevin dynamics simulations are employed to explore the effects of chain stiffness and electrostatic interaction(EI) on the conformational behavior of a circular semiflexible polyelectrolyte(CSPE) in presence of tri...
关键词：Langevin dynamics simulation Circular semiflexible polyelectrolyte Trivalent counterions Electrostatic interaction 
Protective efficacy of an H5/H7 trivalent inactivated vaccine(H5-Re13,H5-Re14, and H7-Re4 strains) in chickens, ducks, and geese against newly detected H5N1, H5N6, H5N8, and H7N9 viruses被引量：19
《Journal of Integrative Agriculture》2022年第7期2086-2094,共9页ZENG Xian-ying HE Xin-wen MENG Fei MA Qi WANG Yan BAO Hong-mei LIU Yan-jing DENG Guo-hua SHI Jian-zhong LI Yan-bing TIAN Guo-bin CHEN Hua-lan 
supported by the National Key Research and Development Program of China(2021YFD1800200);the Laboratory for Lingnan Modern Agriculture Project(NT2021007);the China Agriculture Research System of the MOF and MARA(CARS-41-G12)。
Some H5 viruses isolated in poultry or wild birds between 2020 and 2021 were found to be antigenically different from the vaccine strains(H5-Re11 and H5-Re12) used in China. In this study, we generated three new recom...
关键词：avian influenza H5/H7 trivalent vaccine H5-Re13 H5-Re14 H7-Re4 strains protective efficacy CHICKENS ducks and geese 
Efficient separation between trivalent americium and lanthanides enabled by a phenanthroline-based polymeric organic framework被引量：1
《Chinese Chemical Letters》2022年第7期3429-3434,共6页Afshin Khayambashi Long Chen Xue Dong Kai Li Zhipeng Wang Linwei He Suresh Annam Lixi Chen Yaxing Wang Matthew V.Sheridan Chao Xu Shuao Wang 
supported by the grants from the National Natural Science Foundation of China(Nos.21825601,21790374,and 21806117)。
Separation of the minor actinides(Am and Cm)from lanthanides in high-level liquid wastes(HLLW)is one of the most challenging chemical separation tasks known owing to their chemical similarities and is highly significa...
关键词：Porous organic framework AMERICIUM LANTHANIDES SEPARATION Stability 
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