Supported by the National Science and Technology Major Projects for Major New Drugs Innovation and Development of China(No.2010ZX09401-305-14), the National Natural Science Foundation of China(Nos.81072210, 81101140) and the Key Technologies R&D Program of Jilin Province of China(Nos. 10ZDGG007, 201015166, 201101066).
Gene therapy is a potentially powerful tool used in cancer therapy. The strength of immune responses in- duced by some strategies is usually low, therefore, the development of agents capable of enhancing these respons...
Supported by the Genetically Modified Organisms Breeding Major Projects, China(No.2009ZX08006-002B);the Key Technologies Research and Development Program of Jilin Province, China(No.10ZDGG007);the Postdoctoral Science Foundation Funded Project of China(No.20100481057)
To analyze the antitumor potential and mechanism of action of simultaneous Newcastle disease virus (NDV) hemagglutinin-neuraminidase(HN) and human interleukin 18(hIL-18) gene transfer in C57BL/6 mice with H22 he...
Supported by the Genetically Modified Organisms Breeding Major Project of China(No.2009ZX08006-002B);the Key Technologies Research and Development Programme of Jilin Province, China(No.10ZDGG007)
To investigate the stimulated activity of T cells and the anti-tumor properties of hemagglutinin-neuraminidase(HN) of Newcastle disease virus(NDV) strain Changchun(NDVcc), the expression of HN gene in hepatoma c...
National natural science foundation item (30471530)
Paramyxovirus Tianjin strain, a new genotype of Sendai virus, was isolated from the lungs of common cotton-eared marmoset that died of severe respiratory infection in the marmoset colonies. The 19.28% IgM positive rat...
Hemagglutinin-neuraminidase (HN) protein was expressed in COS-7 cells, indicating that the expression of HN protein driven by SRα promoter is higher than that driven by chicken β-actin promoter. Moreover, with 5' no...