supported by the Science and Technology Support Plan Key Projects of Tianjin(Grant No.20YFZCSY00070);the National Natural Science Foundation of China(Grant Nos.82073276,82273100);the China Digestive Tumor Clinical Scientific Research Public Welfare Project(Grant No.P014-058);Science and Technology project of Health Commission of Tianjin Binhai New Area(Grant No.2022BWKY016).
Aberrant activation of the WNT signaling pathway is a joint event in colorectal cancer(CRC),but the molecular mechanism is still unclear.Recently,RNA-splicing factor LSM12(like-Sm protein 12)is highly expressed in CRC...
National Natural Science Foundation of China,Grant/Award Number:31872487。
Rabies virus(RABV)is an infectious and neurotropic pathogen that causes rabies and infects humans and almost all warm-blooded animals,posing a great threat to people and public safety.It is well known that innate immu...
financially supported by the National Natural Science Foundation of China,No.81371366(to HFW);Characteristic Innovation Project of Colleges and Universities in Guangdong Province of China,No.2018KTSCX075(to HFW);the Key Project of Social Development of Dongguan of China,No.20185071521640(to HFW);College Students’ Science and Technology Innovation Training Project,China,Nos.201810571058,GDMU2018024,GDMU2018056,GDMU2018061(to HFW);College Students’ Innovative Experimental Project in Guangdong Medical University,China,No.ZZDS001(to HFW);College Students’ Science and Technology Innovation Cultivation Project in Guangdong of China,No.pdjh2019b0217(to HFW)
Long non-coding RNAs(lncRNAs)are abundantly expressed in the central nervous system and exert a critical role in gene regulation via multiple biological processes.To uncover the functional significance and molecular m...
Supported by the State Administration of Traditional Chinese Medicine of Guangdong Province,China(No.2009231)
Objective: To investigate the underlying mechanisms of cyclovirobuxinum D(Cvb-D) on alleviating cardiac hypertrophy in rats. Methods: Sprague-Dawley rats were randomly divided into 5 groups: control group; levoth...
Background Breast cancer is one of the most common malignant female diseases worldwide.It is a significant threat to every woman's health.Vascular endothelial growth inhibitor (VEGI) is known to be abundant in endo...
This work was supported by the grants from the National Natural Science Foundation of China (No. 30600265, No. 30871119 and No. 81070024) and from Science and Technology Department of Sichuan Province (No. 10FZ0043).
Objective It is known that Siglec-8 is selectively expressed on human eosinophils at a high level and mediates eosinophil apoptosis when crosslinked with its antibody. The aim of our review is to elucidate the molecul...
Supported by The Fundamental Research Funds for the Central Universities of China,No.20103020101000197
AIM:To investigate the mechanisms of the biological roles of Dickkopf-3(Dkk-3) in cell invasion,survival and apoptosis in colon cancer cells.METHODS:Three human colon cancer cell lines,i.e.,HT-29,LoVo and SW480,were u...
Supported by the National Natural Science Foundation of China(No.30471769)
With biodegradable material poly(ethylene glycol)-poly(lactide-co-glycolide) (PEG-PLGA) as substrate, the size distribution of Rg3-NPs was approved by the scanning electron microscopy. MTT assay was used to dete...