云南高校图书馆联盟文献共享服务平台- CURE

CURE: 作品数：330被引量：620H指数：12; 导出分析报告; 相关作者：张金明尹超陈利跃曾鸣王军更多>>; 相关机构：山东丰源轮胎制造股份有限公司华东理工大学天津大学四川大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划江苏省“六大人才高峰”高层次人才项目中国博士后科学基金更多>>

Drug development for chronic hepatitis B functional cure:Recent progress: 《World Journal of Hepatology》2025年第4期31-42,共12页Ting Liu He Wang Yue Zhao Ying-Xin Wang Xue Xing Peng Gao; Chronic hepatitis B virus(HBV)infection affects approximately 254 million individuals globally,contributing to significant morbidity and mortality due to HBV-related liver failure and cirrhosis,which result in million...; 关键词：Chronic hepatitis B infection Therapeutic targets Monoclonal antibody RNA interference IMMUNOMODULATORS

Hepatitis B core-related antigen as a promising serological marker for monitoring hepatitis B virus cure: 《World Journal of Hepatology》2025年第1期18-28,共11页Yue Qiu Qiao Tang Xiao-Qing Liu Yun-Ling Xue Yi Zeng Peng Hu; Supported by The Chongqing Talents Project,No.cstc2021ycjh-bgzxm0150;The First Batch of Key Disciplines on Public Health in Chongqing,The Health Commission of Chongqing,No.2022(72);The Remarkable Innovation-Clinical Research Project,The Second Affiliated Hospital of Chongqing Medical University;The Scientific and Technological Research Program of Chongqing Municipal Education Commission,the Second Affiliated Hospital of Chongqing Medical University,No.KJZD-K202300404.; Hepatitis B virus(HBV)infection is a global health concern.The current sequen-tial endpoints for the treatment of HBV infection include viral suppression,hepatitis B e antigen(HBeAg)seroconversion,functional cure,and ...; 关键词：Hepatitis B Hepatitis B core-related antigen Hepatitis B surface antigen Hepatitis B virus DNA Covalently closed circular DNA Hepatitis B virus cure

Manipulating the 4-1BB Pathway to Cure HBV: 《Infectious Diseases & Immunity》2024年第4期156-157,共2页Zhang Chao Wang Fu-Sheng; supported by the National Key Research and Development Program of China(2022YFA1303600 and 2023YFC2308100);the National Natural Science Foundation of China(82130019).; Chronic Hepatitis B Virus(HBV)infection is a major global health issue leading to liver cirrhosis and hepatocellular carcinoma.Currently available treatments have limited efficacy in completely eradicating the virus.; 关键词：CIRRHOSIS INFECTION HEPATOCELLULAR

CAR-T Therapy in HIV:Pioneering Advances and Navigating Challenges: 《Infectious Diseases & Immunity》2024年第4期194-205,共12页Xiao Wang Jianyang Liu Feike Hao Tatchapon Ajavavarakula Xuanling Shi; supported by the National Key Research and Development Program of China(2022YFC2604100);the National Science and Technology Major Project(2018ZX10302104-003).; Chimeric antigen receptor T(CAR-T)cell therapy,renowned for its successes in cancer treatment,is now entering the field of human immunodeficiency virus(HIV)therapy,presenting both opportunities and challenges.With the...; 关键词：HIV AIDS CAR-T cell therapy functional cure immune cells

Current trends and advances in antiviral therapy for chronic hepatitis B: 《Chinese Medical Journal》2024年第23期2821-2832,共12页Juan Li Siyi Liu Qijuan Zang Ruijie Yang Yingren Zhao Yingli He; supported by the National Natural Science Foundation of China Grants 82070641;the Clinical Research Award of the First Affiliated Hospital of Xi’an Jiaotong University,China(Nos.XJTU1AF2021CRF-006 and 2022-XKCRC-04);The funding sources were not involved in the study design,writing the manuscript,or decision to submit it for publication.; Chronic hepatitis B virus(HBV)infection is a global public health concern.Existing antiviral drugs,including nucleos(t)ide analogs and interferon-α,can suppress HBV replication and improve the prognosis.However,the p...; 关键词：Antiviral therapy Chronic hepatitis B Functional cure Complete cure

Recurrence and influencing factors of hepatitis B surface antigen seroclearance induced by peginterferon alpha-based regimens: 《World Journal of Gastroenterology》2024年第44期4725-4737,共13页Rui Lu Meng Zhang Zi-Han Liu Miao Hao Yan Tian Mei Li Feng-Ping Wu Wen-Jun Wang Juan-Juan Shi Xin Zhang Xiao-Li Jia Zi-Cheng Jiang Xue-Mei Li Guang-Hua Xu Ya-Ping Li Shuang-Suo Dang; Supported by National Key Research and Development Program of China,No.2023YFC2308105.; BACKGROUND The long-term stability of hepatitis B surface antigen(HBsAg)seroclearance following peginterferon alpha(peg-IFN-α)-based therapy has not been extensively studied,leaving the full potential and limitations...; 关键词：Chronic hepatitis B Peginterferon alpha Hepatitis B surface antigen seroclearance Hepatitis B surface antigen recurrence Clinical cure

Neural stem cell-derived exosomes:a cell-free transplant for potential cure of neurological diseases: 《BIOCELL》2024年第10期1405-1418,共14页JIAJUN HUANG WEI WANG WENTONG LIN HENGSEN CAI ZHIHAN ZHU WAQAS AHMED QIANKUN ZHANG JIALE LIU YIFAN ZHANG RONG LI ZHINUO LI AHSAN ALI KHAN DENG LU YONG HU LUKUI CHEN; Degeneration and death of nerve cells are inevitable with the occurrence and progression of nervous system disorders.Researchers transplanted neural stem cells into relevant areas,trying to solve the difficulty of neu...; 关键词：Stem cells EXOSOMES Nervous system diseases Neural regeneration Neural restoration Cell-free therapy

Earthquakes and Sustainable Infrastructure- Neodeterministic (NDSHA) Approach Guarantees Prevention Rather Than Cure: 《Earthquake Science》2024年第5期494-497,共4页Zengping Wen Guoxin Wang; supported by National Natural Science Foundation of China(No.U2039207).; The reduction of seismic disaster risk hinges on the reliable assessment of seismic hazard.In the realm of seismic hazard assessment(SHA),there have historically been two methods:the probabilistic SHA(PSHA)and the det...; 关键词：HAZARD seismic DISASTER

Cure of Varicocele under Local Anesthesia: Impact on Sperm Parameters: 《Open Journal of Urology》2024年第10期507-513,共7页Babacar Sine Arsen Ngoie Mudiangombe Ndeye Aissatou Bagayogo Amath Thiam Omar Cissokho Moustaf Cheikh Ahmed Abdoulaye Ndiath Ibrahima Cisse Babacar Diao Khassim Ndoye Alain; Introduction: Varicocele is one of the most frequent causes of infertility. There are several therapeutic modalities, namely surgery (open and laparoscopic) and conventional radiology. The aim of our study was to eval...; 关键词：VARICOCELE Local Anesthesia Spermogram

Functional cure of chronic hepatitis B-hope or hype?: 《World Journal of Hepatology》2024年第9期1199-1205,共7页Gautam Ray; Chronic hepatitis B constitutes a substantial disease burden worldwide.The steps advocated by the World Health Organization in 2016 to eradicate hepatitis B by 2030 has failed to achieve significant progress,especiall...; 关键词：Hepatitis B DRUGS Clinical trial THERAPY Novel therapies Functional cure

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