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作品数：115被引量：450H指数：12
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相关领域：医药卫生农业科学更多>>
相关作者：朱剑常英军郭瑞臣倪梅媛余萍更多>>
相关机构：华中科技大学湖南省肿瘤医院北京大学四川省肿瘤医院更多>>
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相关基金：国家自然科学基金广东省自然科学基金中国博士后科学基金国家科技重大专项更多>>
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Efficacy and safety of minocycline in retinitis pigmentosa:a prospective,open-label,single-arm trial
《Signal Transduction and Targeted Therapy》2025年第1期271-277,共7页Yuxi Chen Yuan Pan Yanyan Xie Yuxun Shi Yao Lu Yiwen Xia Wenru Su Xiaoqing Chen Zuoyi Li Minzhen Wang Siyu Miao Yating Yang Chenjin Jin Guangwei Luo Shixian Long Hui Xiao Chuangxin Huang Jian Zhang Dan Liang 
supported by the Sun Yat-sen University Clinical Research 5010 Program(2018012).
Retinitis pigmentosa(RP)is characterized by progressive photoreceptor cells death accelerated by the proliferation and activation of microglia pathologically.No consensus exists on the treatment.Minocycline is recogni...
关键词：protective PROSPECTIVE adapted 
Danning tablets for the treatment of multiple gallbladder polyps: Study protocol of multicentre, randomised, open-labelled, controlled trial
《iLIVER》2024年第4期56-61,共6页Tian Yang Ming-Da Wang Gui-Lin Xie Xiong-Hua Wang Liu Zheng Li-Min Wang Guang-Fa Xiao Yong-Qing Yang Chao Li Alfred Wei Chieh Kow Feng Shen 
funding from Shanghai Hutchison Pharmaceuticals Company.
Introduction:Gallbladder polyps(GPs)are protrusions of the gallbladder wall into the lumen,and are commonly detected during ultrasound examinations.Traditional management of multiple GPs(MGPs)has been conservative,inc...
关键词：Multiple gallbladder polyps Danning tablets SIZE Lifestyle intervention 
“Flow” Transcranial Direct Current Stimulation (tDCS) for Depression Treatment in a Primary Healthcare General Practice—An Open-Label Cohort Study Measuring Montgomery-Åsberg Depression Rating Scale (MADRS-S) Outcomes
《Open Journal of Psychiatry》2024年第4期386-399,共14页Chris Griffiths Harmony Jiang David Smart Azhar Zafar 
Background: Flow FL-100 is a transcranial direct current stimulation (tDCS) device self-administered by a patient at home in combination with a software application delivered wellbeing behaviour therapy training. tDCS...
关键词：DEPRESSION Transcranial Direct Current Stimulation Wellbeing General Practice 
Effectiveness and safety of Shenfu injection in septic patients with hypoperfusion:A multi-center,open-label,randomized,controlled trial
《Journal of Intensive Medicine》2024年第4期484-490,共7页Di Liu Tingting Pan Xiang Li Duming Zhu Yingchuan Li Hongyu He Fang Wu Lijing Jiang Yang Chen Xiaoli Wang Jialin Liu Ruoming Tan Hongping Qu 
supported by the Shanghai Municipal Health and Family Planning Commission General Hospital Chinese and Western Medicine Clinical Cooperation Pilot Construction Project,grant number:ZY(2018-2020)-FWTX-1108.
Background:To evaluate the effectiveness and safety of the Shenfu injection(SFI)combined with standard bundle treatment in septic patients with hypoperfusion.Method:This study was a multi-center,randomized,open-label,...
关键词：SEPSIS Shenfu injection Traditional Chinese medicine Prognosis 
Efficacy and safety of anlotinib plus penpulimab as second-line treatment for small cell lung cancer:A multicenter,open-label,single-arm phase Ⅱ trial
《Cancer Pathogenesis and Therapy》2024年第4期268-275,共8页Changgong Zhang Jianhua Chen Huijuan Wu Jun Wang Liying Gao Jun Zhao Yan Sun Zhongyao Jia Xinlin Mu Chunmei Bai Rui Wang Kailiang Wu Qiang Liu Yuankai Shi 
supported by the National Science and Technology Major Project for Key New Drug Development(No.2017ZX09304015).
Background:Currently,the need for new therapeutic strategies involving programmed cell death protein-1(PD-1)monoclonal antibodies in the second-line setting of small cell lung cancer(SCLC)is urgent.This study aimed to...
关键词：Anlotinib Penpulimab Small cell lung cancer EFFICACY Safety PhaseⅡtrial 
Corrigendum: Efficacy and safety of darbepoetin alfa injection replacing epoetin alfa injection for the treatment of renal anemia in Chinese hemodialysis patients: A randomized, open-label, parallel-group, noninferiority phase Ⅲ trial
《Chronic Diseases and Translational Medicine》2024年第4期350-350,共1页
In the article titled,"Efficacy and safety of darbepoetin alfa injection replacing epoetin alfa injection for the treatment of renal anemia in Chinese hemodialysis patients:A randomized,open-label,parallel-group,nonin...
关键词：TREATMENT INJECTION registered 
Perioperative sintilimab and neoadjuvant anlotinib plus chemotherapy for resectable non-small-cell lung cancer:a multicentre,open-label,single-arm,phase 2 trial(TD-NeoFOUR trial)
《Signal Transduction and Targeted Therapy》2024年第11期5310-5318,共9页Hongtao Duan Changjian Shao Zhilin Luo Tianhu Wang Liping Tong Honggang Liu Xin Yao Jie Lei Jinbo Zhao Yuan Gao Tao Jiang Xiaolong Yan 
funded by the National Natural Science Foundation of China(Grant No.82173252);the Miaozi Talent Fund of Tangdu Hospital,Air Force Medical University.
This open-label,single-arm,phase 2 trial evaluated the efficacy and safety of neoadjuvant sintilimab combined with anlotinib and chemotherapy,followed by adjuvant sintilimab,for resectable NSCLC.Forty-five patients re...
关键词：CHEMOTHERAPY NEOADJUVANT PHASE 
Efficacy of Mometasone Furoate Nasal Spray in Delayed Antibiotic Prescriptions for Acute Rhinosinusitis: A Multicenter, Randomized, Open-Label, Comparative, Prospective, Parallel Group Study
《International Journal of Otolaryngology and Head & Neck Surgery》2024年第5期321-343,共23页Vasyl Popovych Ivanna Koshel Vitalii Leshak Oleksandr Malofiichuk Liubov Piletska Natalia Kapustina Oksana Martynnyk Volodimir Kuderskyi 
While their clinical presentation is similar, post-viral rhinosinusitis does not indicate the possible development of bacterial rhinosinusitis which occurs in only 0.5% to 5% of all cases of ARS. However, unreasonable...
关键词：RHINOSINUSITIS Mometasone Furoate Delayed Antibiotic 
Oral Administration of Nicotinamide Mononucleotide with Bioenhancer BioPerine® Increases the Serum Concentration of Nicotinamide Adenine Dinucleotide in Healthy Human Volunteers: A Pilot, Open-Label, Cross-Over Study
《Advances in Bioscience and Biotechnology》2024年第10期573-589,共17页Anju Majeed Shaheen Majeed Thontadarya Shivakumar Satish Gudimallam Kadlajji Parameshwarappa Avinash Vasantha Nagaraju Lakshmi Mundkur 
Background: Bioenhancers augment the bioavailability of co-administered molecules without showing any significant effect on their own. Piperine, an alkaloid from Piper nigrum, is an established natural bioenhancer. Ni...
关键词：BIOAVAILABILITY BioPerine® Nicotinamide Mononucleotide Nicotinamide Adenine Dinucleotide Bioenhancer 
Subcutaneous daratumumab in Chinese patients with relapsed or refractory multiple myeloma:an open-label,multicenter,phase 1 study(MMY1010)
《Blood Science》2024年第3期42-47,共6页Gang An Zheng Ge Hongmei Jing Jing Liu Guoping Yang Ru Feng Zhongyuan Xu Ming Qi Jianping Wang Juanjuan Song Wei Zhou Binbin Sun Dian Zhu Xi Chen Canchan Cui Lugui Qiu 
Despite recent progress in multiple myeloma(MM)treatments,most patients will relapse and require additional treatment.Intravenous daratumumab,a human IgGκmonoclonal antibody targeting CD38,has shown good efficacy in ...
关键词：Chinese Daratumumab Multiple myeloma PHARMACOKINETIC Relapse/refractory Safety SUBCUTANEOUS 
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