LEONURINE

作品数：7被引量：26H指数：2
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相关领域：医药卫生更多>>
相关作者：刘海超罗姗姗古险峰杜媛媛李姝雅更多>>
相关机构：河北医科大学第二医院复旦大学更多>>
相关期刊：《Chinese Journal of Integrative Medicine》《Journal of Chinese Pharmaceutical Sciences》《Proceedings of Anticancer Research》《Frontiers of Agricultural Science and Engineering》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Multi-omics:Powerful accelerator for uncovering plant specialized metabolic pathways:The case of leonurine
《Molecular Plant》2024年第1期13-15,共3页Priyanka Gupta Anuj Sharma Dinesh A.Nagegowda 
supported by grants from the Department of Biotechnology,Govt.of India(project no.GAP-483:BT/PR37968/GET/119/341/2020).P.G.and A.S.are supported by DBT-SRF and UGC-SRF,respectively。
As sessile organisms,plants employ a unique adaptive strategy to survive harsh terrestrial environments and defend against or interact with coevolving animals and microorganisms.This strategy involves expanding their ...
关键词：EXPANDING ALKALOIDS sulfur 
Multiomics analyses of two Leonurus species illuminate leonurine biosynthesis and its evolution被引量：1
《Molecular Plant》2024年第1期158-177,共20页Peng Li Meng-Xiao Yan Pan Liu Dan-Jie Yang Ze-Kun He Yun Gao Yan Jiang Yu Kong Xin Zhong Sheng Wu Jun Yang Hong-Xia Wang Yan-Bo Huang Le Wang Xiao-Ya Chen Yong-Hong Hu Qing Zhao Ping Xu 
supported by the National Natural Science Foundation of China(32170349 to P.X.);the Chenshan Special Fund for the Shanghai Landscaping Administration Bureau Program(G232402 to P.X.);the Ministry of Science and Technology of the People's Republic of China(YDZX20223100001003 to Y.-H.H.).
The Lamiaceae family is renowned for its terpenoid-based medicinal components,but Leonurus,which has traditional medicinal uses,stands out for its alkaloid-rich composition.Leonurine,the principal active compound foun...
关键词：Lamiaceae Leonurus japonicus Leonurus sibiricus genome sequence ALKALOIDS LEONURINE gene cluster biosynthetic pathway EVOLUTION 
Research Progress on the Neuroprotective Effect of Leonurine on Ischemic Stroke
《Proceedings of Anticancer Research》2021年第6期83-85,共3页Honglong Wu Long He Zhifen Tan Meikui Zhang 
supported by the General Project of Beijing Natural Science Funds-Study on the Effect of Naoshuning,a Traditional Chinese Medicine,for Activating Blood,Promoting Blood Circulation,Removing Water,and Dredging the Internal Organs,on Nerve Regeneration and Its Mechanism in Acute Ischemic Stroke(Fund Number:7182156).
Leonurus is one of the commonly used clinical drugs in traditional Chinese medicine.In recent years,leonurus has been widely used for cerebrovascular diseases.With the deepening of research,the effect of its main comp...
关键词：LEONURINE Ischemic stroke NEUROPROTECTION 
Leonurine: From Gynecologic Medicine to Pleiotropic Agent被引量：12
《Chinese Journal of Integrative Medicine》2020年第2期152-160,共9页LI Yun-yun LIN Yi-kong LIU Xin-hua WANG Li YU Min LI Da-jin ZHU Yi-zhun DU Mei-rong 
Leonurus japonicus Houtt,a Chinese traditional herbal medicine,has been widely used to cure gynecological diseases,such as incomplete abortion and menoxenia.Leonurine,a major active alkaloid compound only be found in ...
关键词：LEONURINE Leonurus japonicus Houtt Chinese medicine oxidative stress inflammation FIBROSIS clinical application 
Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels被引量：12
《Frontiers of Agricultural Science and Engineering》2019年第2期197-205,共9页Shilei ZHENG Jingru ZHU Jiao LI Shuang ZHANG Yunfei MA 
supported by the National Natural Science Foundation of China(31772686 and 31502025);the Public Service Sectors Agriculture Research Projects of Ministry of Agriculture of China(201403051-07)
The present study was designed to investigate the protective effects of leonurine, a compound purified from Herba Leonuri that is active on ischemic rat behavior and cortical neurons, and explore the underlying mechan...
关键词：cerebral ISCHEMIA GABA NEUROPROTECTION LEONURINE SOD 
Six-step synthesis of Leonurine and toxicity study on zebrafish被引量：1
《Chinese Chemical Letters》2017年第6期1172-1175,共4页Hui Zhao Xiang-Guo Hu Min-Jie Xu Qun-Xing Cai Yu-Jun Liu Duo-Meng Su Shi-Jin Chen Kai Wang Zhu-Nan Gong 
supported by Anhui Ph.D.Programs of Postdoctoral Workstation,Talents Program of Hefei;funds from the sixth group of Anhui '115' Industrial Innovation Team(Team of Key Technology Innovation on Botanical Pesticides)
Leonurine（1）,an important ingredient in leonurus sibiricus L,can be used for some gynecological disease.We have developed a concise and efficient synthetic route of Leonurine,which can be optimized for mass producti...
关键词：Leonurine Zebrafish Synthesis Toxcity Oxime 
Improved synthesis of leonurine as cardioprotective agent
《Journal of Chinese Pharmaceutical Sciences》2012年第4期292-295,共4页罗姗姗 古险峰 朱依谆 
National Science Foundation of China (Grant No. 21002013);New Teacher Foundation from Ministry of Education in China (Grant No. 20090071120);Foundation of State Key Laboratory of Natural and Biomimetic Drugs (K20100106);National Basic Research Program of China (973 Program,Grant No. 2010CB912600);STCSM (Grant No. 10431903200)
A new synthetic method of leonurine was developed. Leonurine 1 was synthesized from the key intermediates 4 and 5, two compounds with high solubility in dichloromethane which allowed the synthetic procedure to be perf...
关键词：LEONURINE Motherwort Cardioprotective agent 
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