The authors examined the original data of their work and noticed a misuse in fig.4D(as shown below on the upper panel,red box).The correct one is shown in fig.4D on the lower panel(red box).Additionally,the authors ad...
supported by the National Nature Science Foundation of China(No.81974102).
Objective:T-LAK-cell-originated protein kinase(TOPK),a PSD95-Disc large-ZO1(PDZ)binding kinase(PBK),is a novel member of the mitogen-activated protein kinase(MAPK)family.Studies have shown that TOPK plays a critical r...
the National Agency for Re-search and Innovation(ANII-Uruguay).
Background:Bladder cancer is the tenth most common cancer worldwide.Considering its high prevalence(vulnerability to multiple recurrences and progression despite local therapy),which leads to a substantial health serv...
Cisplatin remains an integral part of the treatment for muscle invasive bladder cancer.A large number of patients do not respond to cisplatin-based chemotherapy and efficacious salvage regimens are limited.Immunothera...
financially supported by the National Natural Science Foundation of China (Nos. 21305148, U1732127, U1432114, 51303196);the Ningbo Natural Science Foundation Nos. 2014A610159, 2014B82010, 2015C50004, 2015B11002, 2016A610013, 2017C110022);Zhejiang Province (Nos. Bsh1202031, 2017C33129, 2017C03042,12018KY737 andLY18H180011);Zhejiang Pharmaceutical College (No. ZPCSR2015013);Hundred Talents Program of Chinese Academy of Sciences (No. 2010-735)
The development of multifunctional contrast agents contributes significant character in the diagnosis of cancer. However, still efforts are required to design and improve the biocompatibility of contrast agents for ea...
Supported by the National Natural Science Foundation of China under Grant Nos 11674383,11774407 and 11874415;the Key Research Program of Frontier Sciences of Chinese Academy of Sciences under Grant No QYZDB-SSW-SLH045;the National Key Research and Development Program under Grant No 2016YFA0301500;the Higher Educational Science and Technology Program of Shandong Province under Grant No J16LM06;the Natural Science Foundation of Shandong Province under Grant No ZR2014AQ025;the Program of Shandong Provincial Government International Exchanges
We investigate the effect of torsion on DNA condensation with the covalently closed circular DNA as the torsionconstrained system, using an atomic force microscope. It is found that there are two stages in the DNA con...
Supported by a Grant of the Korea Health Technology R&D Project through the Korea Health Industry Development Institute(KHIDI);funded by the Ministry of Health&Welfare,Republic of Korea(No.HI14C0750)
Objective: To examinie the synergistic effects of Banxia Xiexin Decoction (半夏泻心汤, Known as Banhasasim-tang in Korean) extract (BXDE) on cisplatin-induced cytotoxicity in the A549 human lung cancer ceil lines...
It is widely accepted that high-intensity focused ultrasound (HIFU) is a minimally invasive treatment option for different tumors, but its roles and the corresponding mechanism in cisplatin (DDP) che- moresistance...
The project supported by National Natural Science Foundation of China(81373439,81473234 and U1303221)
OBJECTIVE Previous work has shown that gap junction intercel ular communication(GJIC)enhances cisplatin(Pt)toxicity in testicular tumor cells but decreases it in non-tumor testicular cells.In this study,these differen...