相关期刊:《International Journal of Ophthalmology(English edition)》《Chinese Medical Journal》《World Journal of Cardiology》《Signal Transduction and Targeted Therapy》更多>>
Objective To evaluate the efficacy and safety of chimeric antigen receptorT-cell(CAR-T)therapy followed byallogeneic hematopoietic stem cell transplantation(allo-HSCT)in patients with Ph-like acute lymphoblastic leuke...
Objective To investigate the safety and efficacy of donor-derived CD19+or sequential CD19+CD22+chimeric antigen receptor T-cell(CAR-T)therapy in patients with B-cell acute lymphoblastic leukemia(BALL)afterallogeneic h...
Objective To explore the efficacy and safety of Venetoclax combined with multidrug chemotherapy in patients with relapsed or refractory early T-cell precursor acute lymphoblastic leukemia(R/R ETP-ALL).Methods This stu...
Macrophage activation syndrome (MAS) is linked to inappropriate stimulation of macrophage cells in the bone marrow and lymphoid system, resulting in abnormal phagocytosis of figurative blood elements and the release o...
Supported by Nanjing Military Region Innovation Project,No.15MS108;and the Youth Nursery Fund,No.18Y024.
BACKGROUND We present a case of focal lymphoblastic transformation to erythroid leukemia following acute myeloblastic transformation in a patient with chronic myelogenous leukemia(CML)and discuss its mechanism of occu...
supported by grants from the National Natural Science Foundation of China(Nos.82070184 and 82270228);sponsored by Beijing Nova Program(No.20220484235);Peking University People’s Hospital Research and Development Funds(No.RDL2021-01)
To the Editor:For recipients with relapsed/refractory(R/R)B-cell acute lymphoblastic leukemia(B-ALL),allogeneic hematopoietic stem cell transplantation(allo-HSCT)often fails to provide them with a satisfactory prognos...
Objective To assess the clinical characteristics and prognosis of patients with SIL-TAL1-positive T-cell acute lymphoblastic leukemia(T-ALL).Methods The clinical data of 19 SIL-TAL1-positive T-ALL patients admitted to...
To the Editor:The fusion gene E2A::HLF(TCF3::HLF)is formed by t(17;19)(q21-22;p13),which presents in<1%of B-cell acute lymphoblastic leukemia(B-ALL)and mainly occurs in older children and adolescents.[1]Such patients ...
National Natural Science Foundation of China(No.31660318);Natural Science Foundation of Hainan Province(No.820RC638);The Innovative research projects for graduates of Hainan Medical University(No.HYYS2020-10)。
Objective:To study the effect of different concentrations of rapamycin on the proliferation of acute leukemia CD4^(+)T-Jurkat cells,and to explore its mechanism from the aspect of autophagy.Methods:The effect of diffe...