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作品数:113被引量:206H指数:7
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相关领域:医药卫生更多>>
相关作者:刘芳任爱国何志义马俊荣徐应军更多>>
相关机构:华北煤炭医学院中国预防医学科学院中国医科大学附属第一医院华中农业大学更多>>
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相关基金:国家自然科学基金国家高技术研究发展计划重庆市自然科学基金国家重点基础研究发展计划更多>>
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Rare mixed dementia:A case report
《World Journal of Radiology》2025年第1期67-75,共9页Xu-Hui Chen Wen Xia Jia-Bin Ma Jiao Chen Jun Hu Xin Shi Jing-Jing Yu Jia Gong Lu Liu Yong-An Sun Zhi-Gang Liu 
Supported by the Shenzhen Science and Technology Program,No.JCYJ20220818102810022;Shenzhen University Teaching Reform fund,No.JG2023166;National Natural Science Foundation of China,No.12231018;Science and Technology Innovation 2030-Major Project,No.2021ZD0201805.
BACKGROUND Autoimmune encephalitis(AE)is a rare and recently described neuroinflammatory disease associated with specific autoantibodies.Anti-leucine-rich glioma inactivated 1(anti-LGI1)encephalitis is a rare but trea...
关键词:Anti-leucine-rich glioma inactivated 1 ENCEPHALITIS Alzheimer’s disease Cognitive impairment Case report 
Single-cell multi-omics analysis revealing immune features of inactivated COVID-19 vaccination in systemic lupus erythematosus patients
《Science Bulletin》2025年第1期42-46,共5页Yuxuan Zheng Siyuan Wang Xingyu Zhou Shitong Qiao Xin Zhao Yuan Chen Zijun Li Zhanguo Li Xiaolin Sun Shuguang Tan Jing He George Fu Gao 
supported by the National Key Research and Development Program of China(2022YFC2604100,2022YFC2302900,2021YFC2301400,and 2022YFE0131700);National Natural Science Foundation of China(92169208,32222031,82071813,32141004,and 82171775);Peking University People’s Hospital Research and Development Funds(RDGS2022-05);National Postdoctoral Program for Innovative Talents of China(BX20220332)。
Studies have focused on neutralizing antibody titers and T-cell activation induced by vaccination against different SARS-CoV-2strains[1,2].Advanced single-cell technology has allowed for a comprehensive evaluation of ...
关键词:VACCINATION REVEALING TITER 
COVID-19 infection and inactivated vaccination:Impacts on clinical and immunological profiles in Chinese children with type 1 diabetes
《World Journal of Diabetes》2024年第12期2276-2284,共9页Zhen-Ran Xu Li Xi Jing Wu Jin-Wen Ni Fei-Hong Luo Miao-Ying Zhang 
Supported by National Key Research and Development Program of China,No.2021YFC2701900 and No.2016YFC1305300.
BACKGROUND The coronavirus disease 2019(COVID-19)pandemic has been linked to an increased incidence of diabetes and diabetic ketoacidosis(DKA).However,the relationship between COVID-19 infection and progression to typ...
关键词:COVID-19 infection Diabetic ketoacidosis Type 1 diabetes VACCINATION Immune profiles 
Acquired immune thrombotic thrombocytopenic purpura(TTP)associated with inactivated COVID-19 vaccine CoronaVac
《Frontiers of Medicine》2024年第4期744-751,共8页Zhangbiao Long Suyu Jiang Honglei Xin Lu Zhang Ruinan Lu Fengqi Liu Yong Xu Linv Wang Jun Wang Xuezhong Zhang Hui Liao Jinning Shi Xue Yan Xiang Zhu Ruonan Shao Zijian Li Yilin Zhu Han Yan Jiao Wu Chao Fang Xiaodong Xi Xiaofeng Shi 
supported by the National Natural Science Foundation of China(Nos.81700130,82370134,92169114,81802932);the Natural Science Fund for Distinguished Young Scholars of Hubei Province(No.2022CFA054);the National Key Research and Development Program of China(No.2018YFE0113600).
Corona virus disease 2019(COVID-19)due to severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection has affected the whole world.Acquired thrombotic thrombocytopenic purpura(TTP)has been reported after admi...
关键词:thrombotic thrombocytopenia purpura(TTP) corona virus disease 2019(COVID-19) CoronaVac acute respiratory syndrome coronavirus 2(SARS-CoV-2) VACCINE 
Safety,immunogenicity and protective effect of sequential vaccination with inactivated and recombinant protein COVID-19 vaccine in the elderly:a prospective longitudinal study
《Signal Transduction and Targeted Therapy》2024年第6期2738-2747,共10页Hong-Hong Liu Yunbo Xie Bao-Peng Yang Huan-Yue Wen Peng-Hui Yang Jin-E Lu Yan Liu Xi Chen Meng-Meng Qu Yang Zhang Wei-Guo Hong Yong-Gang Li Junliang Fu Fu-Sheng Wang 
supported by Guangzhou Laboratory,Grant Award Number:EKPG21-30-4.
The safety and efficacy of COVID-19 vaccines in the elderly,a high-risk group for severe COVID-19 infection,have not been fully understood.To clarify these issues,this prospective study followed up 157 elderly and 73 ...
关键词:VACCINATION VACCINE doses 
Immune response to inactivated bacterial vector carrying the recombinant K39 antigen of Leishmania infantum in mice
《Asian Pacific Journal of Tropical Biomedicine》2024年第5期199-206,共8页Lucelina S.Araújo Bruno B.Silva Eduarda N.F.N.Santos Arnaldo S.Bezerra Samuel S.Frota Assis R.Montenegro Eridan O.P.T.Florean Maurício Fvan Tilburg Maria Izabel F.Guedes 
supported by grants from the Brazilian Agencies:Coordenação de Aperfeiçoamento de Pessoal de Nível Superior(CAPES-Financial code 001);Conselho Nacional de Desenvolvimento Científico e Tecnológico(CNPq);Fundação Cearense de Apoio ao Desenvolvimento Científico e Tecnológico(FUNCAP).
Objective:To evaluate the immunological response elicited by an inactivated bacterial vector carrying the K39 antigen of Leishmania infantum,and a purified antigen.Methods:Mice were subjected to the following treatmen...
关键词:Visceral leishmaniasis K39 Inactivated bacterial vector Vaccine Immune response Th1 TH2 Leishmania infantum 
Effect of diabetes mellitus on antibody levels in elderly individuals after vaccination with inactivated SARS-CoV-2 vaccine
《感染控制(英文)》2024年第1期60-67,共8页Wen Guo Yu Cao Yingmei Feng 
Background We explored the influence of diabetes on the antibody levels of elderly individuals after inoculation with an inactivated vaccine against severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)and the f...
关键词:inactivated vaccine against SARS-CoV-2 DIABETES IgG antibody neutralizing antibody 
Safety and Immunogenicity After Primary and Booster Inactivated SARS-Cov-2 Vaccination in Patients with Autoimmune Liver Diseases
《Journal of Clinical and Translational Hepatology》2024年第2期162-171,共10页Zhiwei Chen Yuting Wang Taiyu He Hu Li Ling Ao Qingbo Pan Yingzhi Zhou Qian Zhu Dejuan Xiang Gaoli Zhang Ning Ling Min Chen Peng Hu Mingli Peng Dachuan Cai Dazhi Zhang Hong Ren 
supported by the National Science and Technology Major Project of China(Nos 2017ZX10202203-007,2017ZX10202203-008,2018ZX10302206-003)and a pilot project of clinical cooperation between traditional Chinese and western medicine for significant and complicated diseases of National Administration of Traditional Chinese Medicine:hepatic fibrosis.We also acknowledge the support of the National Natural Science Foundation of China(No 81772198);Natural Science Foundation of Chongqing,China(No.cstc2020jcyjmsxmX0389).
Background and Aims:SARS-CoV-2 vaccines-associated autoimmune liver diseases have been reported in several case reports.However,the safety and immunogenicity after primary and booster inactivated SARS-CoV-2 vaccinatio...
关键词:SARS-CoV-2 Autoimmune liver disease Inactivated SARS-CoV-2 vaccine SAFETY Antibody responses Memory B cells 
Does the homologous booster with the inactivated coronavirus disease 2019 vaccine work for the omicron variant?Real-world evidence from Jilin,China
《Chinese Medical Journal》2023年第23期2892-2894,共3页Jun Guo Lei Zha Kai Zeng Mingyu Shao Dan Chen Bing Wang Yun Zhou Gang Yang Xue Zhang Xia Zou Yan Zhang Yan Kang 
Key Research and Development Project of the Science and Technology Department of Sichuan Province(No.2021YFS0003,Zygd18020);High-level Talents Fund of the Wuhu Municipal Government(No.2021-134)
To the Editor:The latest variant of concern,Omicron,has become the dominant global variant immediately after it was first reported in November 2021.[1]It contains>30 mutations in the spike protein,with 17 mutations in...
关键词:VACCINATION HOMOLOGOUS RENDERING 
以头颈部水肿为表现的遗传性血管性水肿分析被引量:1
《中国耳鼻咽喉头颈外科》2023年第12期800-801,共2页张敏 李茂才 刘付星 宫丽丽 
目的 分析以头颈部水肿为主要表现的遗传性血管性水肿的治疗方法,以期对其更加深入的了解。方法 回顾性分析2017年6月~2021年4月于聊城市人民医院耳鼻咽喉头颈外科住院的遗传性血管性水肿患者,其中男1例,女3例,年龄23~55岁。结果 4例患...
关键词:血管性水肿 遗传性(Angioedemas Hereditary) C1酯酶抑制因子(C1 inhibitor) 灭活血浆(inactivated plasma) 
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