supported by the National Key R&D Program of China(2022YFA1504302);the National Natural Science Foundation of China(92256302,22331011);the Natural Science Foundation of Jiangsu Province(BK20211092);the Major Program of the Lanzhou Institute of Chemical Physics,Chinese Academy of Sciences(ZYFZFX-9);the Lanzhou Institute of Chemical Physics,Chinese Academy of Sciences;the Hangzhou Normal University。
Reported here is an iridium-catalyzed enantio-divergent C(sp^(3))–H borylation ofα-gem-dimethyl groups of trifluoromethyl ketone-derived hydrazones to construct a series of acyclic all-carbon quaternary stereocenter...
We gratefully acknowledge NSFC(Grant No.22101177);the Science and Technology Commission of Shanghai Municipality(Grant Nos.23YF1426700 and 21ZR1442000);start-up funding of ShanghaiTech University for their generous financial support.
Organoborons are commonly used building blocks for rapidly increasing molecular complexity.Although significant progress has been made in the selective functionalization of mono-organoborons,the site-selective functio...
financial support from National Natural Science Foundation of China(22071187,22271226);Natural Science Foundation of Hubei Province(2021CFA069);National Youth Talent Support Program。
Transition metal-catalyzed asymmetric hydrogenation is an efficient and direct synthetic method to access chiral compounds,which features simplicity,easy working-up process,and high atomic economy.It typically relies ...
the National Natural Science Foundation of China(22277053 to X.H.;223B2703 to Y.X.);the National Key Research and Development Program of China(2022YFA0913000 to X.H.);the Natural Science Foundation of Jiangsu Province(BK20220760 to X.H.);the Fundamental Research Funds for the Central Universities(0205/14380346 to X.H.);the Excellent Research Program of Nanjing University(ZYJH004 to X.H.).
Enzymes are natural treasure troves that hold multiple superiority.Enzymatic catalysis has become a powerful tool for asymmetric synthesis,though it is typically limited to a relatively narrow range of reaction types....
financial support from the supported by National Natural Science Foundation of China(Nos.22061008 and 22361008);the State Key Laboratory of Natural and Biomimetic Drugs(No.K202223);the Science and Technology Foundation of Guizhou Province(Nos.ZK[2021]-039 and[2023]-097);the State Key Laboratory of Functions and Applications of Medicinal Plants,Guizhou Medical University(No.FAMP202102K).
Allenes are a class of unsaturated compounds containing a propadiene structural moiety,exhibiting essential physiological,pharmacological,and various reactivities.Their(4+3)cycloaddition reaction has become an effecti...
supported by the National Natural Science Foundation of China(Nos.21871293,22071264).
Chiral phosphine-catalyzed asymmetric(4+2)annulation of the amide-based Morita–Baylis–Hillman(MBH)carbonates withβ,γ-unsaturated butenolides has been developed to give enantiomer-enriched bicyclicδ-lactamγ-butyr...
supported by the National Key R&D Program of China(2022YFA1503702,2021YFF0701600);the National Natural Science Foundation of China(22325110,92256303,21821002,22171280);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB0610000);the Program of Shanghai Academic Research Leader(22XD1424900);the CAS Youth Interdisciplinary Team(JCTD-2021-11)and the Ningbo Natural Science Foundation(2022J017).
Transition-metal-catalyzed asymmetric alkylation of aldehydes represents a straightforward strategy for the synthesis of chiral secondary alcohols.However,efficient methods using organoborons as coupling reagents are ...
supported by the National Natural Science Foundation of China (21871116, U22A20390);the Fundamental Research Funds for the Central Universities (lzujbky-2023-stlt01);the“111” program from the MOE of China。
Organocatalytic cascade reactions represent a powerful strategy for the rapid construction of complex chiral molecules with multiple stereocenters from simple substrates under mild conditions. The intriguing structura...
supported by the National Natural Science Foundation of China(grant no.21901185);funds provided by Tianjin Normal University,China.
Herein,we disclose a ligand-controlled,directing group-assisted strategy to facilitate NiH-catalyzed hydroalkynylation of allyl amides at remoteα-position adjacent to nitrogen and initial olefinic site in a predictab...
the Key Research and Development Program of the Ministry of Science and Technology of China(2023YFA1508600);the start-up funding from Wuhan University.
As a versatile earth-abundant transition metal,Cu has long been widely applied in the C—C and C—X bond forming reactions.As for now,low-valent Cu(Ⅰ)is known to reduce the redox active electrophiles via an SET pathw...