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作品数:1542被引量:2818H指数:17
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相关领域:理学更多>>
相关作者:吴骊珠孟庆元佟振合张强刘娜更多>>
相关机构:中国科学院清华大学华东理工大学中国科学院大学更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划中国博士后科学基金北京市自然科学基金更多>>
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Enantio-divergent C–H borylation with two different ligands from a single chiral source
《Science China Chemistry》2025年第1期226-232,共7页Rongrong Du Senmiao Xu 
supported by the National Key R&D Program of China(2022YFA1504302);the National Natural Science Foundation of China(92256302,22331011);the Natural Science Foundation of Jiangsu Province(BK20211092);the Major Program of the Lanzhou Institute of Chemical Physics,Chinese Academy of Sciences(ZYFZFX-9);the Lanzhou Institute of Chemical Physics,Chinese Academy of Sciences;the Hangzhou Normal University。
Reported here is an iridium-catalyzed enantio-divergent C(sp^(3))–H borylation ofα-gem-dimethyl groups of trifluoromethyl ketone-derived hydrazones to construct a series of acyclic all-carbon quaternary stereocenter...
关键词:asymmetric catalysis C–H borylation all-carbon quaternary stereocenters synthetic methods 
Catalytic Selective Functionalization of Poly(organoborons)
《Chinese Journal of Chemistry》2024年第24期3484-3498,共15页Jia-Hui Zhao Ang Chen Xi-Zhang Zou Chong-Lei Ji Huang-Di Feng De-Wei Gao 
We gratefully acknowledge NSFC(Grant No.22101177);the Science and Technology Commission of Shanghai Municipality(Grant Nos.23YF1426700 and 21ZR1442000);start-up funding of ShanghaiTech University for their generous financial support.
Organoborons are commonly used building blocks for rapidly increasing molecular complexity.Although significant progress has been made in the selective functionalization of mono-organoborons,the site-selective functio...
关键词:Poly(organoborons) Selective functionalization Asymmetric catalysis CROSS-COUPLING PHOTOCATALYSIS 
Earth-Abundant Nickel-Catalyzed Asymmetric Hydrogenation
《Chinese Journal of Chemistry》2024年第23期3135-3156,共22页Peng Wang Zhao-Lin He Zi-Fei Xia Jun Wei Xiu-Qin Dong 
financial support from National Natural Science Foundation of China(22071187,22271226);Natural Science Foundation of Hubei Province(2021CFA069);National Youth Talent Support Program。
Transition metal-catalyzed asymmetric hydrogenation is an efficient and direct synthetic method to access chiral compounds,which features simplicity,easy working-up process,and high atomic economy.It typically relies ...
关键词:Transition metal Nickel HYDROGENATION ENANTIOSELECTIVITY Asymmetric catalysis Earth-abundant metal 
Repurposing Naturally Occurring Enzymes Using Visible Light
《Chinese Journal of Chemistry》2024年第24期3553-3558,共6页Yuanyuan Xu Fulu Liu Beibei Zhao Xiaoqiang Huang 
the National Natural Science Foundation of China(22277053 to X.H.;223B2703 to Y.X.);the National Key Research and Development Program of China(2022YFA0913000 to X.H.);the Natural Science Foundation of Jiangsu Province(BK20220760 to X.H.);the Fundamental Research Funds for the Central Universities(0205/14380346 to X.H.);the Excellent Research Program of Nanjing University(ZYJH004 to X.H.).
Enzymes are natural treasure troves that hold multiple superiority.Enzymatic catalysis has become a powerful tool for asymmetric synthesis,though it is typically limited to a relatively narrow range of reaction types....
关键词:Photoenzymatic catalysis New-to-nature reactivity Asymmetric catalysis Enzyme catalysis Photoredox catalysis 
Recent advances in(4+3)cycloaddition of allenes
《Green Synthesis and Catalysis》2024年第4期270-276,共7页Yanyan Que Wenli Lei Yin Fang Shuzhong He Yang Chen 
financial support from the supported by National Natural Science Foundation of China(Nos.22061008 and 22361008);the State Key Laboratory of Natural and Biomimetic Drugs(No.K202223);the Science and Technology Foundation of Guizhou Province(Nos.ZK[2021]-039 and[2023]-097);the State Key Laboratory of Functions and Applications of Medicinal Plants,Guizhou Medical University(No.FAMP202102K).
Allenes are a class of unsaturated compounds containing a propadiene structural moiety,exhibiting essential physiological,pharmacological,and various reactivities.Their(4+3)cycloaddition reaction has become an effecti...
关键词:ALLENES (4+3)Cycloaddition Asymmetric catalysis Seven-membered heterocycles 
Amide-Based Morita–Baylis–Hillman Carbonates for Phosphine-Catalyzed Asymmetric(4+2)Annulation
《Chinese Journal of Chemistry》2024年第24期3269-3277,共9页Min Liu Qihuan Han Lan Wang Xi Chen Xue Zhang Hongchao Guo 
supported by the National Natural Science Foundation of China(Nos.21871293,22071264).
Chiral phosphine-catalyzed asymmetric(4+2)annulation of the amide-based Morita–Baylis–Hillman(MBH)carbonates withβ,γ-unsaturated butenolides has been developed to give enantiomer-enriched bicyclicδ-lactamγ-butyr...
关键词:Asymmetric catalysis Asymmetric synthesis Phosphine catalysis Organocatalysis Cycloaddition ANNULATION AMIDE MBH carbonate LACTAM Piperidinone Heterocycle 
Enantioselective Alkylation of Aldehydes with Organoborons Enabled by Nickel/N-Heterocyclic Carbene Catalysis
《Chinese Journal of Chemistry》2024年第18期2161-2165,共5页Song-Yang Liu Zi-Chao Wang Shi-Liang Shi 
supported by the National Key R&D Program of China(2022YFA1503702,2021YFF0701600);the National Natural Science Foundation of China(22325110,92256303,21821002,22171280);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB0610000);the Program of Shanghai Academic Research Leader(22XD1424900);the CAS Youth Interdisciplinary Team(JCTD-2021-11)and the Ningbo Natural Science Foundation(2022J017).
Transition-metal-catalyzed asymmetric alkylation of aldehydes represents a straightforward strategy for the synthesis of chiral secondary alcohols.However,efficient methods using organoborons as coupling reagents are ...
关键词:Enantioselective alkylation Nickel catalysis N-Heterocyclic carbene Organoborons Chiral alcohols Asymmetric catalysis C-C coupling Synthetic methods 
Catalytically generated noncovalent ammonium dienolate:a versatile platform for the development of organocatalytic asymmetric cascade reactions
《Science China Chemistry》2024年第8期2524-2546,共23页Jun-Bing Lin Dong-Sheng Ji Peng-Fei Xu 
supported by the National Natural Science Foundation of China (21871116, U22A20390);the Fundamental Research Funds for the Central Universities (lzujbky-2023-stlt01);the“111” program from the MOE of China。
Organocatalytic cascade reactions represent a powerful strategy for the rapid construction of complex chiral molecules with multiple stereocenters from simple substrates under mild conditions. The intriguing structura...
关键词:ORGANOCATALYSIS asymmetric catalysis ammonium dienolate cascade reaction difunctionalization 
Asymmetric NiH-Catalyzed Regioselective Hydroalkynylation of Unactivated Alkenes
《CCS Chemistry》2024年第8期1929-1940,共12页Mengyuan Liu Haoran Shi Xiao Meng Rui He Jie Huang Jiaxin Wang Jun Lv Chao Wang 
supported by the National Natural Science Foundation of China(grant no.21901185);funds provided by Tianjin Normal University,China.
Herein,we disclose a ligand-controlled,directing group-assisted strategy to facilitate NiH-catalyzed hydroalkynylation of allyl amides at remoteα-position adjacent to nitrogen and initial olefinic site in a predictab...
关键词:asymmetric catalysis hydroalkynylation regiodivergent chain-walking nickel catalysis 
Copper Catalyzed Enantioconvergent Nucleophilic Substitutions
《Chinese Journal of Chemistry》2024年第10期1161-1174,共14页Chunxi Huang Zilong Wan Aoping Zhu Caiyou Chen 
the Key Research and Development Program of the Ministry of Science and Technology of China(2023YFA1508600);the start-up funding from Wuhan University.
As a versatile earth-abundant transition metal,Cu has long been widely applied in the C—C and C—X bond forming reactions.As for now,low-valent Cu(Ⅰ)is known to reduce the redox active electrophiles via an SET pathw...
关键词:Enantioconvergent Nucleophilic substitution COPPER Radical reactions PHOTOCATALYSIS Asymmetric catalysis 
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