CELL-FREE

作品数：148被引量：425H指数：12
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Circulating cell-free mtDNA as a new biomarker for cancer detection and management
《Cancer Biology & Medicine》2024年第2期105-110,共6页Fan Peng Siyuan Wang Zehui Feng Kaixiang Zhou Huanqin Zhang Xu Guo Jinliang Xing Yang Liu 
the National Natural Science Foundation of China(Grant No.81830070)。
Cancer is a major cause of death worldwide,and was responsible for 19.29 million new cases and 9.96 million deaths in 2020 alone.The total number of patients with cancer worldwide is estimated to reach 28 million by 2...
关键词：CANCER CANCER DEATH 
Aptamer-based cell-free detection system to detect target protein被引量：1
《Synthetic and Systems Biotechnology》2021年第3期209-215,共7页Junhong Chen Xiaoyan Zhuang Jiyang Zheng Ruofan Yang Fei Wu Aihui Zhang Baishan Fang 
financially supported by the National Natural Science Foundation of China(No.21978245)。
Biomarkers of disease,especially protein,show great potential for diagnosis and prognosis.For detecting a certain protein,a binding assay implementing antibodies is commonly performed.However,antibodies are not therma...
关键词：APTAMER CRISPR-Cas Protein detection BIOMARKER 
Circular RNA and its potential as prostate cancer biomarkers被引量：1
《World Journal of Clinical Oncology》2020年第8期563-572,共10页Dwayne Tucker Wei Zheng Da-Hong Zhang Xuesen Dong 
Advancing knowledge of the transcriptome has revealed that circular RNAs(circRNAs)are widely expressed and evolutionarily conserved molecules that may serve relevant biological roles.More interesting is the accumulati...
关键词：Circular RNA RNA splicing Prostate cancer BIOMARKER Cell-free RNA 
Prognostic and predictive blood biomarkers in gastric cancer and the potential application of circulating tumor cells被引量：22
《World Journal of Gastroenterology》2018年第21期2236-2246,共11页Ting-Ting Li Hao Liu Jiang Yu Guang-Yao Shi Li-Ying Zhao Guo-Xin Li 
Supported by the Guangdong Provincial Natural Science Foundation,No.2016A030313843
Gastric cancer(GC), with its high incidence and mortality rates, is a highly fatal cancer that is common in East Asia particularly in China. Its recurrence and metastasis are the main causes of its poor prognosis. Cir...
关键词：GASTRIC cancer BIOMARKER CIRCULATING tumor cells AUTOANTIBODIES CELL-FREE DNA 
Liquid biopsy in patients with hepatocellular carcinoma: Circulating tumor cells and cell-free nucleic acids被引量：25
《World Journal of Gastroenterology》2017年第31期5650-5668,共19页wataru okajima shuhei komatsu daisuke ichikawa mahito miyamae takuma ohashi taisuke imamura jun kiuchi keiji nishibeppu tomohiro arita hirotaka konishi atsushi shiozaki ryo morimura hisashi ikoma kazuma okamoto eigo otsuji 
Hepatocellular carcinoma(HCC), with its high incidence and mortality rate, is one of the most common malignant tumors. Despite recent development of a diagnostic and treatment method, the prognosis of HCC remains poor...
关键词：Hepatocellular carcinoma BIOMARKER Liquid biopsy Circulating tumor cells Cell-free nucleic acids 
Isolation of Cell-Free DNA from Seminal Fluid
《Journal of Pharmacy and Pharmacology》2017年第8期554-560,共7页Tina Draskovic 
Cell-flee DNA （cfDNA） is small short double stranded molecule that is also found in seminal fluid. It is a product ofapoptotic cells in different developmental stages during spermatogenesis. To final concentration o...
关键词：CELL-FREE DNA  seminal fluid  diagnostic biomarker  PROSTATE cancer  male infertility  CELL-FREE DNA isolation  problems ofcell-free DNA measurement. 
Circulating Tumor DNA as Biomarkers for CancerDetection被引量：9
《Genomics, Proteomics & Bioinformatics》2017年第2期59-72,共14页Xiao Han Junyun Wang Yingli Sun 
supported by the Precision Medicine Research Program of the Chinese Academy of Sciences (Grant No. KJZD-EW-L14);the National Basic Research Program of China (973 Program; Grant Nos. 2012CB518302 and 2013CB911001);the National Natural Science Foundation of China (Grant Nos. 31540033 and 91019024);the Strategic Priority Research Program of the Chinese Academy of Sciences (Grant No. XDA01040407)
Detection of circulating tumor DNAs(ct DNAs) in cancer patients is an important component of cancer precision medicine ct DNAs. Compared to the traditional physical and biochemical methods, blood-based ct DNA detectio...
关键词：Precision medicine Liquid biopsy Circulating tumor DNA BIOMARKER Clinical diagnosis Cell-free nucleic acids 
Liquid biopsy of gastric cancer patients:Circulating tumor cells and cell-free nucleic acids被引量：9
《World Journal of Gastroenterology》2014年第12期3265-3286,共22页Masahiro Tsujiura Daisuke Ichikawa Hirotaka Konishi Shuhei Komatsu Atsushi Shiozaki Eigo Otsuji 
To improve the clinical outcomes of cancer patients, early detection and accurate monitoring of diseases are necessary. Numerous genetic and epigenetic alterations contribute to oncogenesis and cancer progression, and...
关键词：Gastric cancer BIOMARKER Liquid biopsy Circulating tumor cells Cell-free nucleic acids MICRORNA 
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