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作品数:608被引量:2365H指数:22
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相关领域:医药卫生更多>>
相关作者:王书奎梅琳洪勇潘智杨宇更多>>
相关机构:南方医科大学复旦大学福建省肿瘤医院中国人民解放军总医院更多>>
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相关基金:国家自然科学基金国家重点基础研究发展计划北京市自然科学基金国家教育部博士点基金更多>>
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Plasma circulating cell–free DNA integrity and relative telomere length as diagnostic biomarkers for Parkinson's disease and multiple system atrophy:a cross-sectional study
《Neural Regeneration Research》2025年第12期3553-3563,共11页Chao Ying Chao Han Yuan Li Mingkai Zhang Shuying Xiao Lifang Zhao Hui Zhang Qian Yu Jing An Wei Mao Yanning Cai 
supported by the National Key Research and Development Program of China,No.2021YFC2501205(to YC);the Science and Technology Innovation 2030 project,No.2021ZD0201101(to YC);the National Natural Science Foundation of China,Nos.82201409(to YL),82201401(to CH);the Xuanwu Youth Development Project,No.QNPY2021011(to CH)。
In clinical specialties focusing on neurological disorders,there is a need for comprehensive and integrated non-invasive,sensitive,and specific testing methods.Both Parkinson's disease and multiple system atrophy are ...
关键词:biomarkers cell-free DNA diagnosis multiple system atrophy neurodegenerative diseases Parkinson’s disease risk factors 
Application of circulating tumor DNA liquid biopsy in nasopharyngeal carcinoma:A case report and review of literature
《World Journal of Clinical Cases》2025年第21期93-103,共11页Xin-Yao Zhou Yuan-Jun Jiang Xiao-Ming Guo Dong-Hui Han Yao Liu Qiao Qiao 
Supported by Beijing Bethune Charitable Foundation and Provincial Natural Science Foundation of Liaoning,No.2022-MS-190.
BACKGROUND Circulating tumor DNA(ctDNA)-based liquid biopsy has been found to be effective for the detection of minimal residual disease and the evaluation of prognostic risk in various solid tumors,with good sensitiv...
关键词:Nasopharyngeal cancer Radiation therapy Circulating tumor DNA Epstein–Barr virus Minor residual disease Guide treatment Predicting prognosis Case report 
Energy Collection from Water Flow Based on Single-Electrode Triboelectric Nanogenerators
《哈尔滨工程大学学报(英文版)》2025年第2期415-427,共13页Shuangyin Chen Chengwang Xiong Jianhua Liu Minyi Xu 
the support from Natural Science Foundation of Heilongjiang Province(No.YQ2022A004);National Natural Science Foundation of China(No.12372268,No.12332014).
As intelligent sensors for marine applications rapidly advance,there is a growing emphasis on developing efficient,low-cost,and sustainable power sources to enhance their performance.With the continuous development of...
关键词:Triboelectric nanogenerator Single electrode Circulating water flow Green energy harvesting Solid‒liquid contact 
A review on pathobiology of circulating tumour plasma cells:The sine qua non of poor prognosis in plasma cell neoplasms
《Oncology Research》2025年第5期1055-1068,共14页PRATIBHA SUKU AISHWARYA DASH ARAVIND RADHAKRISHNAN PANKAJ MALHOTRA MAN UPDESH SINGH SACHDEVA 
Circulating plasma cells(CPCs)in patients of plasma cell neoplasm have been an area of intense research in recent decades.Circulating tumor plasma cells(CTPCs)might represent a sub-clone of tumor cells that have exite...
关键词:Circulating Plasma Cells(CPCs) Multiple Myeloma(MM) Flow cytometry Circulating Tumor Plasma Cells(CTPCs) Microenvironment Monoclonal gammopathy 
Exercise preconditioning alleviates ischemia-induced memory deficits by increasing circulating adiponectin
《Neural Regeneration Research》2025年第5期1445-1454,共10页Meifeng Zheng Borui Zhang Sonata S Y Yau Kwok-Fai So Li Zhang Haining Ou 
supported by STI2030-Major Projects,No.2022ZD0207600(to LZ);the National Natural Science Foundation of China,Nos.32070955(to LZ),U22A20301(to KFS);the Natural Science Foundation of Guangdong Province,No.2021A1515012197(to HO);Guangzhou Core Medical Disciplines Project,No.2021-2023(to HO);Key Research and Development Plan of Ningxia Hui Automomous Region,No.2022BEG01004(to KFS);Science and Technology Program of Guangzhou,China,No.202007030012(to KFS and LZ)。
Cerebral ischemia is a major health risk that requires preventive approaches in addition to drug therapy.Physical exercise enhances neurogenesis and synaptogenesis,and has been widely used for functional rehabilitatio...
关键词:ADIPONECTIN cerebral ischemia exercise pre-conditioning HIPPOCAMPUS memory function middle cerebral artery occlusion prefrontal cortex synaptic proteins treadmill exercise 
Circulating circular RNAs act as potential novel biomarkers for sepsis secondary to pneumonia:a prospective cohort study
《World Journal of Emergency Medicine》2025年第2期144-152,共9页Chunxue Wang Dianyin Yang Yuxin Zhu Qian Yang Tong Liu Xiandong Liu Dongyang Zhao Xiaowei Bao Tiancao Dong Li Shao Lunxian Tang 
supported by grants from the municipal Natural Science Foundation of Shanghai Scientific Committee of China(22ZR1451000 to TL);the peak supporting clinical discipline of Shanghai Health Bureau(2023ZDFC0104 to TL);the key clinical discipline of Shanghai Pudong Health Bureau(PWZxk2022-17 to TL);the clinical peak discipline of Shanghai Pudong Heath Bureau(PWYgf2021-03);the top-notch innovative medical talents of Shanghai Pudong Health Bureau(2025PDWSYCBJ-03 to TL);the leading medical talent project of Shanghai Pudong Heath Bureau(PWR12020-07 to LS)。
BACKGROUND:Circulating biomarkers for sepsis are lacking,and research on circular RNAs(circR NAs)as potential biomarkers of pneumonia-induced sepsis is limited.This study aims to investigate the diagnostic and prognos...
关键词:Circular RNAs BIOMARKER Pneumonia-induced sepsis Diagnosis Prognosis 
Epidemiology and Genetic Evolution of Influenza B Viruses Circulating in the Democratic Republic of Congo from 2015 to 2022: Implication of Vaccination
《Open Journal of Respiratory Diseases》2025年第1期1-18,共18页Edith Nkwembe Ngabana Youdhie Ituneme N’ka Flabo Grace Mufwaya Makayi Leonie Manya Kitoto Saleh Muhemedi Kayumba Pélagie Babakazo Hugo Kavunga Membo Steve Ahuka Mundeke 
Introduction: Influenza A (Flu A) and B (Flu B) viruses are responsible for severe acute respiratory infections (SARI) worldwide, with a morbidity of 5 million and mortality of 29,000 - 650,000 deaths per year. Influe...
关键词:EPIDEMIOLOGY Genetic Evolution Influenza B Viruses DRC 
Cholangiocarcinoma:The era of liquid biopsy
《World Journal of Gastroenterology》2025年第11期14-32,共19页Evgenia Kotsifa Francesca Saffioti Vasileios K Mavroeidis 
Cholangiocarcinoma(CCA)is a highly aggressive and heterogeneous malignancy arising from the epithelial cells of the biliary tract.The limitations of the current methods in the diagnosis of CCA highlight the urgent nee...
关键词:Biliary tract cancer CHOLANGIOCARCINOMA Circulating tumour cells Cell free DNA Circulating tumour DNA Circulating RNA Biomarkers Extracellular vesicles Precision medicine 
Catching cancer signals in the blood:Innovative pathways for early esophageal cancer diagnosis
《World Journal of Gastroenterology》2025年第10期1-6,共6页Yue Zhao Zhan Zhang Jian-Hao Qiu Rong-Yang Li Zhen-Guo Sun 
Supported by The National Key R and D Program of China,No.2021YFC2500904,No.2021YFC2500905 and No.2021YFC2500900;Shandong Provincial Natural Science Foundation,No.ZR2023MH130 and No.ZR2017BH035;China Postdoctoral Science Foundation,No.2020M672073;National Natural Science Foundation of China,No.81802397.
In recent years,significant progress has been made in the application of DNA methylation for the early detection of esophageal cancer(EC).As an epigenetic modification,DNA methylation allows for noninvasive screening ...
关键词:Esophageal cancer DNA methylation Circulating tumor DNA Early detection Liquid biopsy Treatment monitoring 
Circulating metabolites of Borneolum syntheticum(Bingpian)ameliorate atherosclerosis in ApoE−/−mice via inhibiting macrophage foam-cell formation
《Acta Pharmacologica Sinica》2025年第3期759-776,共18页Rong-rong He Chuan-rui Ma Xin He Yan-xi Dong Hui Li Zi-xuan Chu Xi-he Yang Jia-qi Wang Ting Wang Feng-qing Wang Fei-fei Du Ying Rao Wen-xuan Yu Xiu-mei Gao Guan-wei Fan Chen Cheng Chuan Li 
funded by grants from the National Natural Science Foundation of China(82192912);National Engineering Research Center of TCM Standardization Technology(2023-ZYBZH-10);National Key R&D Program“Strategic Scientific and Technological Innovation Cooperation”Key Project(2022YFE0203600).
Translational pharmacological research on traditional medicines lays the foundation for precisely understanding how the medicines function in the body to deliver therapeutic benefits.Borneolum syntheticum(Bingpian)is ...
关键词:Borneolum syntheticum Bingpian BORNEOL ISOBORNEOL metabolism ATHEROSCLEROSIS 
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