Dear Editor,Liver transplantation(LT)is the best option for the treatment of both cirrhosis and hepatocellular carcinoma(HCC),providing the best long-term outcomes,particularly for patients within the Milan criteria[1...
Combined Hepatocellular-Cholangiocarcinoma is a heterogenous primary malignant epithelial tumor of the liver with variable morphological and immunophenotypical features.Although the biology of this tumor has been desc...
Systemic treatment is the optimal approach for patients with advanced or intermediate-stage hepatocellular carcinoma(HCC)with contraindications or refractoriness to locoregional treatments[1].The aim of systemic treat...
This is an Erratum of the publsihed paper:Long-term survival of occult hepatitis B associated hepatocellular carcinoma following surgery and antiviral therapy.The ethical approval and consent to participation informat...
funding from the Wellcome Trust(Grant ref 110110/Z/15/Z);the Francis Crick Institute,London.
The increasing incidence and mortality of hepatocellular carcinoma(HCC)driven by hepatitis B virus(HBV)infection is a global public health concern[1].Despite World Health Organization(WHO)targets for the elimination o...
Guest Editor:Professor Jose J.G.Marin Carlos III National Institute of Health,Spain Submission begins:November 1,2016 Possible submission deadline:May 1,2017 Dear Friends and Colleagues,Greetings!I hope that you will ...
This work was supported by grant(2015CB554006)from the National Key Basic Research Program of China(GC)
The chronic infection of hepatitis B virus(HBV)is the major cause of hepatocellular carcinoma(HCC)globally[1].In Eastern China,chronic HBV infection contributes to 87.5%of HCC whereas chronic hepatitis C virus(HCV)inf...
This work was supported by National Key Basic Research Program of China(No.2015CB554000).
Aim:Immune checkpoint inhibitors(ICIs)are proven to be an effective way to treat the disease of hematologic malignancies.But there is still plenty of uncertainty about the effectiveness of ICIs on hepatocellular carci...
This work was supported by the National Major Special Science and Technology Project(2017ZX10203207);Graduate Course Construction Project of Guangxi Medical University(YJSA2017014);the Foundation Ability Enhancement Project for Young Teachers in Guangxi Universities(2018KY0122),the Guangxi Natural Science Foundation(2018GXNSFBA138018),and Guangxi BaGui Young Scholars.
Due to the prevelence of hepatitis B virus(HBV)and hepatitis C virus(HCV),occurrence of hepatocellular carcinoma(HCC)is increasing in many countries/regions,including China[1].
This work was supported by grants from the National Natural Science Foundation of China(81572312);Chinese National Key Project Specialized for Infectious Diseases(2017ZX10201201-008-003);National Key Research and Development Program of China(2017YFC0908103);Chinese State Key Laboratory of Oncogenes and Related Genes(91-14-16,91-15-06).
Through several studies exploiting next-generation sequencing,we are obtaining a clearer picture of the complex genetic and molecular landscape of hepatocellular carcinoma(HCC).Consistent with the findings of other ca...