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Associations of content and gene polymorphism of macrophage inhibitory factor-1 and chronic hepatitis C virus infection被引量：2
《World Journal of Gastroenterology》2020年第41期6378-6390,共13页Xun-Jun Yang Xiao-Ou Wang Yao Chen Song-Dao Ye 
Supported by the Medical and Health Research Science and Technology Plan Project of Zhejiang Province,No. 2016KYB191。
BACKGROUND The expression of macrophage inhibitory factor-1(MIC-1) is increased in peripheral blood of patients with chronic hepatitis and liver cirrhosis. However, whether MIC-1 gene polymorphism is correlated with r...
关键词：Hepatitis C virus Chronic infection Exon region Polymorphism Macrophage inhibitory factor-1 Case-control study 
Is exon mutation analysis needed for adjuvant treatment of gastrointestinal stromal tumor?被引量：1
《World Journal of Gastroenterology》2013年第1期144-146,共3页Mehmet Ali Nahit Sendur Nuriye Yildirim zdemir Muhammed Bülent Akinci Dogan Uncu Nurullah Zengin Sercan Aksoy 
Gastrointestinal stromal tumors(GISTs) are the most common soft tissue sarcoma of the gastrointestinal tract,resulting from an activating mutation of stem cell factor receptor(KIT),and an activating mutation of the ho...
关键词：IMATINIB Gastrointestinal stromal tumor Activating MUTATION Stem cell FACTOR RECEPTOR PLATELET-DERIVED growth FACTOR RECEPTOR alpha MUTATION analysis 
KIT exon 11 codon 557/558 deletion/insertion mutations define a subset of gastrointestinal stromal tumors with malignant potential被引量：4
《World Journal of Gastroenterology》2008年第12期1891-1897,共7页Katerina Kontogianni-Katsarou Euthimios Dimitriadis Constantina Lariou Evi Kairi-Vassilatou Nikolaos Pandis Agatha Kondi-Paphiti 
Supported by The Hellenic State Scholarship Foundation, Dept of Science Promotion, 2005 Grant for Scientific Research. No. 19366/2005
AIM: To study the association of the frequency and pattern of KIT and PDGFRA mutations and clinicopathological factors in a group of patients with gastrointestinal stromal tumors (GIST). METHODS: Thirty patients with ...
关键词：Gastrointestinal stromal tumors KIT gene Platelet derived growth factor receptor alpha MUTATIONS MALIGNANT 
Role of the intracellular receptor domain of gp130 (exon 17) in human inflammatory bowel disease
《World Journal of Gastroenterology》2005年第8期1196-1199,共4页Christoph J.Auernhammer Kathrin Zitzmann Fabian Schnitzler Julia Seiderer Peter Lohse George Vlotides Dieter Engelhardt Michael Sackmann Burkhard G(o|¨)ke Thomas Ochsenkühn 
Supported by the Department of Clinical Chemistry - Grosshadem, Ludwig-Maximilians-University
AIM: To study the role of the intracellular receptor domain of gp130 in human inflammatory bowel disease (IBD).METHODS: We amplified and sequenced the complete exon 17 of the human gp130 gene in 146 patients with IBD....
关键词：Exon 17 Inflammatory bowel disease gp130 gene 
Expression of proliferating cell nuclear antigen and CD44 variant exon 6 in primary tumors and corresponding lymph node metastases of colorectal carcinoma with Dukes'stage C or D被引量：37
《World Journal of Gastroenterology》2003年第7期1482-1486,共5页Ji-ChenqZhang Zuo-RenWang Yan-JuanCheng Ding-ZhongYang Jing-SenShi Ai-LinLiang Ning-NaLiu Xiao-MinWang 
AIM: To study changes in characteristics of colorectal carcinoma during the metastatic process and to investigate the correlation between cell proliferation activity and metastatic ability of patients with Dukes′ sta...
关键词：结肠直肠癌 淋巴结转移癌 细胞增殖 CD44v6 增殖细胞核抗原 
Codon 249 mutation in exon 7 of p53 gene in plasma DNA:maybe a new early diagnostic marker of hepatocellular carcinoma in Qidong risk area,China被引量：18
《World Journal of Gastroenterology》2003年第4期692-695,共4页Xing-HuaHuang Lu-HongSun Dong-DongLu YanSun Li-JieMa Xi-RanZhang JianHuang LongYu 
AIM: One of the characteristics of hepatocellular carcinoma (HCC) in Qidong area is the selective mutation resulting in a serine substitution at codon 249 of the p53 gene (1,20),and it has been identified as a 'hotspo...
关键词：P53基因 血浆 DNA 肝细胞癌 肿瘤标志物 早期诊断 高发地区 
Establishment of a transgenic cell line stably expressing human cytochrome P450 2C18 and identification of a CYP2C18 clone with exon 5 missing被引量：6
《World Journal of Gastroenterology》2002年第5期888-892,共5页JianZhu-GE Ying-NianYu 
National Natural Science Foundation of China,No.39770868;Natural Science Foundation of Zhejiang Province,No.397490.
AIM: The human cytochrome P-450 2C18(CYP2C18) hasbeen characterized. However, the protein has not beenpurified from liver and very little is known regarding thespecific substrate of CYP2C18. In order to study its enzy...
关键词：转基因细胞 P450细胞色素 第5外显子丢失 CYP2C18 鉴定 克隆 
Cloning and sequence analysis of human genomic DNA of augmenter of liver regeneration被引量：13
《World Journal of Gastroenterology》2000年第2期275-277,共3页Cheng J Zhong YW Liu Y Dong J Yang JZ Chen JM 
INTRODUCTIONThe liver is one of the organs,which have potentialregenerative capability in mammalian animal.The study of the canine model indicated that theliver could regenerate to original size after 70%hepatectomy i...
关键词：augmenter liver REGENERATION CLONING GENOMIC DNA INTRON EXON 
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