This work was partly supported by the National Key R&D Program of China(No.2022YFB3808100);This work was supported by National Natural Science Foundation of China(Nos.81873835 and 82071726);the Suzhou Science and Technology Plan(No.SKY2022005);the Gusu Talent Project of Suzhou(No.GSWS2020011);the Science and Technology Project of Suzhou(No.SKY2023138);the research fund of the Second Affiliated Hospital of Soochow University(No.SDFEYGZ2319).
Uterine infertility is a major global issue causing substantial physical and psychological hardship for individuals struggling to conceive,while endometrium injury is one of the crucial factors causing infertility.Her...
supported by the National Science Fund for Distinguished Young Scholars(No:81901099 and 81703427);the 64th batch of China Postdoctoral Science Foundation(No:2018M641731).
All eukaryotic cells can secrete extracellular vesicles, which have a double-membrane structure and are important players in the intercellular communication involved in a variety of important biological processes. Pla...
supported by grants from the National Natural Science Foundation of China[grant numbers 12032003 and 12102261].
We have shown that platelet-derived microvesicles(PMVs)induce abnormal proliferation,migration,and energy metabolism of vascular smooth muscle cells(VSMCs)after vascular intimal injury.Here,we examined a novel role of...
supported by Scientific Research Program of Tianjin Education Commission(Natural Science)of China,No.2019ZD034(to QJD).
Extracellular vesicles are composed of fragments of exfoliated plasma membrane,organelles or nuclei and are released after cell activation,apoptosis or destruction.Platelet-derived extracellular vesicles are the most ...
This research was supported by grants from the National Natural Science Foundation of China,No.11625209.
During vascular remodeling after intimal injury,circulating platelets are activated by exposed collagen and release platelet-derived microvesicles(PMVs),which may contribute to the injury-induced apoptosis of vascular...
AIM: To determine the effect of pirfenidone on the activated human Müller cells by platelet-derived growth factor-BB(PDGF-BB). METHODS: The primary human Müller cells were separated from retinal tissues and establis...
Background:Acute kidney injury (AKI) is a severe disease in critically ill patients.Neutrophil infiltration into kidney was associated with the development of AKI,and P-selectin may be involved in the process of ne...
Objective:To study the correlation of serum PDGF and Ang-2 contents with atherosclerotic plaque features in patients with coronary heart disease.Methods: A total of 80 patients with coronary heart disease who were tre...
Objective:To study the effect of recombinant human platelet-derived growth factor (rhPDGF) gel on wound healing as well as inflammation and angiogenesis in the wound of rats with diabetes ulcer. Methods:Clean male Wis...
the grant from the National Natural Science Foundation of China
Background: Systemic lupus eiLythenaatosus (SLE) is a prototypic autoimmune disease wida complex genetic inheritance. This study was conducted to examine whether the association ofa proliferation-inducing ligand (...