PLATELET-DERIVED

作品数:26被引量:34H指数:4
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相关领域:医药卫生更多>>
相关作者:张珉李坚张擎更多>>
相关机构:第二军医大学中山大学更多>>
相关期刊:《Journal of Biomedical Science and Engineering》《Asian Journal of Pharmaceutical Sciences》《癌症》《World Journal of Clinical Oncology》更多>>
相关基金:国家自然科学基金更多>>
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Platelet-derived extracellular vesicles for endometrial regeneration towards efficient live birth
《Nano Research》2025年第2期607-615,共9页Dongxiao Li Yanhong Yang Bo Tian Chenmeng Zhou Shuting Gu Wenju Chang Bingbing Wu Dantong Dong Fang Xu Ziyang Yu Ling Zhou Chao Wang Hong Zhang 
This work was partly supported by the National Key R&D Program of China(No.2022YFB3808100);This work was supported by National Natural Science Foundation of China(Nos.81873835 and 82071726);the Suzhou Science and Technology Plan(No.SKY2022005);the Gusu Talent Project of Suzhou(No.GSWS2020011);the Science and Technology Project of Suzhou(No.SKY2023138);the research fund of the Second Affiliated Hospital of Soochow University(No.SDFEYGZ2319).
Uterine infertility is a major global issue causing substantial physical and psychological hardship for individuals struggling to conceive,while endometrium injury is one of the crucial factors causing infertility.Her...
关键词:endometrium regeneration fertility restoration platelet-derived extracellular vesicles platelet-rich plasma 
Platelet-derived microparticles and their cargos: The past, present and future
《Asian Journal of Pharmaceutical Sciences》2024年第2期72-88,共17页Jingwen Guo Bufeng Cui Jie Zheng Chang Yu Xuran Zheng Lixin Yi Simeng Zhang Keke Wang 
supported by the National Science Fund for Distinguished Young Scholars(No:81901099 and 81703427);the 64th batch of China Postdoctoral Science Foundation(No:2018M641731).
All eukaryotic cells can secrete extracellular vesicles, which have a double-membrane structure and are important players in the intercellular communication involved in a variety of important biological processes. Pla...
关键词:Platelet-derived particles Application Heter ogeneity Potential and limitations 
Platelet-derived microvesicles drive vascular smooth muscle cell migration via forming podosomes and promoting matrix metalloproteinase-9 activity被引量:1
《Mechanobiology in Medicine》2023年第1期44-50,共7页He Ren Jiahe Chen Kai Huang Ying-Xin Qi 
supported by grants from the National Natural Science Foundation of China[grant numbers 12032003 and 12102261].
We have shown that platelet-derived microvesicles(PMVs)induce abnormal proliferation,migration,and energy metabolism of vascular smooth muscle cells(VSMCs)after vascular intimal injury.Here,we examined a novel role of...
关键词:Platelet-derived microvesicles(PMVs) Vascular smooth muscle cells(VSMCs) PODOSOME Matrix metalloproteinase-9(MMP-9) Migration 
Role of platelet-derived extracellular vesicles in traumatic brain injury-induced coagulopathy and inflammation被引量:1
《Neural Regeneration Research》2022年第10期2102-2107,共6页Liang Liu Quan-Jun Deng 
supported by Scientific Research Program of Tianjin Education Commission(Natural Science)of China,No.2019ZD034(to QJD).
Extracellular vesicles are composed of fragments of exfoliated plasma membrane,organelles or nuclei and are released after cell activation,apoptosis or destruction.Platelet-derived extracellular vesicles are the most ...
关键词:ANGIOGENESIS clotting factors COAGULOPATHY delivery INFLAMMATION platelet-derived extracellular vesicles review TARGET traumatic brain injury 
Platelet-derived microvesicles deliver miR-30e and promote VSMC apoptosis after balloon injury
《Medicine in Novel Technology and Devices》2022年第1期22-30,共9页Li Zi-Tong Chen Yuan-Xiu Bao Han Liu Ji-Ting Zhuang Fei Li Hai-Peng Yao Qing-Ping Jiang Zong-Lai Qi Ying-Xin 
This research was supported by grants from the National Natural Science Foundation of China,No.11625209.
During vascular remodeling after intimal injury,circulating platelets are activated by exposed collagen and release platelet-derived microvesicles(PMVs),which may contribute to the injury-induced apoptosis of vascular...
关键词:Platelet-derived microvesicles Vascular smooth muscle cells APOPTOSIS miR-30e RUNX2 Intimal injury 
Pirfenidone suppresses the abnormal activation of human Müller cells after platelet-derived growth factor-BB stimulation被引量:4
《International Journal of Ophthalmology(English edition)》2019年第7期1075-1082,共8页Yi-Jin Tao Qin Chen Li Wang Xiao Yang Qing Cun Wen-Yan Yang Hua Zhong 
AIM: To determine the effect of pirfenidone on the activated human Müller cells by platelet-derived growth factor-BB(PDGF-BB). METHODS: The primary human Müller cells were separated from retinal tissues and establis...
关键词:pirfenidone Müller CELLS PLATELET-DERIVED GROWTH factor-BB transforming GROWTH factor-β proliferative VITREORETINOPATHY 
Effect of Platelet-derived P-selectin on Neutrophil Recruitment in a Mouse Model of Sepsis-induced Acute Kidney Injury被引量:6
《Chinese Medical Journal》2017年第14期1694-1699,共6页Xiu-Hua Li Yong-Bing Qian Xiao-Xiao Meng Rui-Lan Wang 
Background:Acute kidney injury (AKI) is a severe disease in critically ill patients.Neutrophil infiltration into kidney was associated with the development of AKI,and P-selectin may be involved in the process of ne...
关键词:Acute Kidney Injury NEUTROPHILS P-SELECTIN SEPSIS 
The correlation of serum PDGF and Ang-2 contents with atherosclerotic plaque features in patients with coronary heart disease
《Journal of Hainan Medical University》2017年第8期39-42,共4页Yan-Bing Xi 
Objective:To study the correlation of serum PDGF and Ang-2 contents with atherosclerotic plaque features in patients with coronary heart disease.Methods: A total of 80 patients with coronary heart disease who were tre...
关键词:Coronary heart disease PLATELET-DERIVED growth factor ANGIOGENIN 2 ATHEROSCLEROTIC PLAQUE 
Effect of rhPDGF gel on wound healing as well as inflammation and angiogenesis in the wound of rats with diabetes ulcer
《Journal of Hainan Medical University》2017年第3期9-12,共4页Ming-Cai Wang Xiao-Hua Yin 
Objective:To study the effect of recombinant human platelet-derived growth factor (rhPDGF) gel on wound healing as well as inflammation and angiogenesis in the wound of rats with diabetes ulcer. Methods:Clean male Wis...
关键词:Type 2 DIABETES mellitus ULCER WOUND PLATELET-DERIVED growth factor INFLAMMATION ANGIOGENESIS 
Association Study of a Proliferation-inducing Ligand, Spermatogenesis Associated 8, Platelet-derived Growth Factor Receptor-alpha, and POLB Polymorphisms with Systemic Lupus Erythematosus in Chinese Han Population被引量:6
《Chinese Medical Journal》2016年第17期2085-2090,共6页Ping Li Yuan Li Ai-Hong Zhou Si Chen Jing Li Xiao-Ting Wen Zi-Yan Wu Liu-Bing Li Feng-Chun Zhang Yong-Zhe Li 
the grant from the National Natural Science Foundation of China
Background: Systemic lupus eiLythenaatosus (SLE) is a prototypic autoimmune disease wida complex genetic inheritance. This study was conducted to examine whether the association ofa proliferation-inducing ligand (...
关键词:A Proliferalion-inducing Ligand Genetic Association Spermatogenesis Associated 8 Systemic Lupus Erythelnatosus Platelet-derivcd Growth Factor Receptor-alpha POLB 
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