HEPACIVIRUS

作品数:17被引量:135H指数:10
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相关领域:医药卫生更多>>
相关期刊:《Science China(Life Sciences)》《Virologica Sinica》《World Journal of Gastroenterology》《World Journal of Clinical Cases》更多>>
相关基金:国家自然科学基金国家高技术研究发展计划更多>>
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Distribution and changes in hepatitis C virus genotype in China from 2010 to 2020被引量:14
《World Journal of Clinical Cases》2022年第14期4480-4493,共14页Jia Yang Hui-Xin Liu Ying-Ying Su Zhi-Sheng Liang Hui-Ying Rao 
BACKGROUND Hepatitis C virus(HCV)causes a large number of infections worldwide.New infections seem to be increasing according to a report of the World Health Organization in 2015.Although direct-acting antivirals are ...
关键词:HEPACIVIRUS GENOTYPE China Drug users Direct-acting antiviral Hepatitis C virus 
Identification and genetic characterization of bovine hepacivirus in China:A large scale epidemiological study
《Virologica Sinica》2022年第2期223-228,共6页Gang Lu Chaoxi Chen Ran Shao Juan Zhang Jinghao Li Siqi Cai Lintao Zhong Zhiying Lai Jiajun Ou Xin Yin Guihong Zhang Shoujun Li 
supported by the Natural Science Foundation of Heilongjiang Province under Grant(JQ 2021C005);Guangdong Provincial Natural Science Foundation under Grant(2017A030310367)。
Bovine hepacivirus(BovHepV)is a novel virus that was recently discovered in Ghana and Germany in 2015.Until now,this virus has been identified in cattle population worldwide and is classified into subtypes A-G.To full...
关键词:Bovine hepacivirus(BovHepV) China EPIDEMIOLOGY Genetic diversity CATTLE 
Identification of a novel hepacivirus in Mongolian gerbil(Meriones unguiculatus)from Shaanxi,China被引量:1
《Virologica Sinica》2022年第2期307-310,共4页Cui-hong An Juan Li Yi-ting Wang Shou-min Nie Wen-hui Chang Hong Zhou Lin Xu Yang-xin Sun Wei-feng Shi Ci-xiu Li 
funded by the Academic Promotion Programme of Shandong First Medical University(2019QL006);the Open Research Fund Program of CAS Key Laboratory of Special Pathogens and Biosafety,Wuhan Institute of Virology(Grant No.2021SPCAS002);W.S.was supported by the Taishan Scholars program of Shandong Province。
Dear Editor,Hepaciviruses,members of the family Flaviviridae,are enveloped viruses containing a single-stranded positive-sense RNA genome of approximately 8.9-10.5 kb in size(Simmonds et al.,2017).To date,15species(He...
关键词:unguiculatus stranded ENVELOPE 
Novel hepacivirus in Asian house shrew, China被引量:1
《Science China(Life Sciences)》2019年第5期701-704,共4页Hua Guo Chunlin Cai Bo Wang Fei Zhuo Rendi Jiang Ning Wang Bei Li Wei Zhang Yan Zhu Yi Fan Wushen Chen Weihong Chen Xinglou Yang Zhengli Shi 
supported by the National Natural Science Foundation of China(81290341);the Basic Research Project of Shenzhen Science and Technology Innovation Program(JCYJ20150402102519532)
Dear Editor,Hepatitis C virus (HCV) is a leading global cause of various liver diseases, including chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. The genome of HCV is monopartite, single-stranded, p...
关键词:RNA In China NOVEL HEPACIVIRUS in ASIAN HOUSE SHREW FIGURE 
Tricistronic hepatitis C virus subgenomic replicon expressing double transgenes
《World Journal of Gastroenterology》2014年第48期18284-18295,共12页Xin Cheng Xiang-Cui Gao Jun-Ping Wang Xin-Ying Yang Yan Wang Bao-Sheng Li Fu-Biao Kang Hai-Jun Li Yue-Min Nan Dian-Xing Sun 
Supported by Grants from the Study on Prevention and Control of Viral Hepatitis in the Key Program for Science and Technology Development of Hebei Province,No.10276102D
AIM: To construct a tricistronic hepatitis C virus (HCV) replicon with double internal ribosome entry sites (IRESes) of only 22 nucleotides for each, substituting the encephalomyocarditis virus (EMCV) IRESes, which ar...
关键词:HEPACIVIRUS REPLICON Internal ribosome entry site Tricistronic expression 
Assessment of correlation between serum titers of hepatitis c virus and severity of liver disease被引量:14
《World Journal of Gastroenterology》2004年第16期2409-2411,共3页BhupinderS.Anand MariaVelez 
AIM:The significance of hepatitis C virus (HCV) serum titers has been examined in several clinical situations. There is much evidence that patients with a lower viral load have better response rates to anti-viral ther...
关键词:ADULT Alanine Transaminase Alcohol Drinking Aspartate Aminotransferases Diagnosis  Differential Genome  Viral HEPACIVIRUS purification Hepatitis C Humans Liver Diseases Liver Function Tests Middle Aged RNA  Viral Regression Analysis Severity of Illness Index Viral Load 
SEN virus does not affect treatment response in hepatitis C virus coinfected patients but SEN virus response depends on SEN virus DNA concentration被引量:2
《World Journal of Gastroenterology》2004年第13期1893-1897,共5页Abdurrahman Sagin Ortwin Adams OliverKirschberg AndreasErhardt TobiasHeintges Dieter Hussinger 
AIM: To clarify the effect of SEN virus (SENV) infection on a combination therapy including interferon alfa (IFN-α) or pegylated-IFN with ribavirin in patients with chronic hepatitis and the effect of a combination t...
关键词:Adult Antiviral Agents DNA Virus Infections DNA Viruses purification DNA  Viral Drug Therapy  Combination Female HEPACIVIRUS Hepatitis C  Chronic Humans Interferon Alfa-2a INTERFERON-ALPHA Male Middle Aged Polyethylene Glycols Prevalence RNA  Viral RIBAVIRIN 
Natural history of chronic hepatitis C in patients on hemodialysis: Case control study with 4-23 years of follow-up被引量:14
《World Journal of Gastroenterology》2004年第15期2209-2212,共4页Kunio Okuda Osamu Yokosuka 
AIM:Hepatitis C virus(HCV)infection is very common among end-stage kidney disease patients on hemodialysis,but its natural history is not known. METHODS:In this study,189 dialysis patients(case) positive for HCV antib...
关键词:Renal Dialysis ADULT Aged Aged  80 and over Case-Control Studies DNA  Viral Female Follow-Up Studies HEPACIVIRUS Hepatitis C  Chronic Humans Male Middle Aged 
Effect of in vitro interferon-beta administration on hepatitis C virus in peripheral blood mononuclear cells as a predictive marker of clinical response to interferon treatment for chronic hepatitis C被引量:13
《World Journal of Gastroenterology》2004年第5期733-736,共4页Kaori Mochizuki Tatehiro Kagawa Shinji Takashimizu Kazuya Kawazoe Sei-Ichiro Kojima Naruhiko Nagata Atsushi Nakano Yasuhiro Nishizaki Koichi Shiraishi Masaru Itakura Norihito Watanabe Tetsuya Mine Shohei Matsuzaki 
AIM:To test whether in vitro incubation of peripheral blood mononuclear cells (PBMC) with interferon (IFN) could efficiently decrease hepatitis C virus-RNA (HCV-RNA) amount and to analyze whether this effect was assoc...
关键词:Adult Antiviral Agents dosage Drug Resistance  Viral Female HEPACIVIRUS Hepatitis C  Chronic Humans In Vitro INTERFERON-BETA Leukocytes  Mononuclear Male Middle Aged Predictive Value of Tests RNA  Viral 
Acute hepatitis C in a chronically HIV-infected patient:Evolution of different viral genomic regions被引量:2
《World Journal of Gastroenterology》2003年第7期1496-1500,共5页Diego Flichman Veronica Kott Silvia Sookoian Rodolfo Campos 
the Universidad de Buenos Aires(SECyT-UBA,TB14);Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET,PIP723);Agencia Nacional de Promoción Científica y Tecnológica(ANPCyT,PICT 01610);Ministerio de Salud Pǘblica de la Nación(Beca Carrillo-Oativia)
AIM: To analyze the molecular evolution of different viral genomic regions of HCV in an acute HCV infected patient chronically infected with HIV through a 42-month follow-up.METHODS: Serum samples of a chronically HIV...
关键词:Acute Disease Adolescent Amino Acid Sequence Female Genome  Viral HIV HIV Envelope Protein gp120 HIV Infections HEPACIVIRUS Hepatitis C Humans Molecular Sequence Data Research Support  Non-U.S. Gov't SUPERINFECTION Viral Nonstructural Proteins Viral Proteins 
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