BACKGROUND Hepatitis C virus(HCV)causes a large number of infections worldwide.New infections seem to be increasing according to a report of the World Health Organization in 2015.Although direct-acting antivirals are ...
supported by the Natural Science Foundation of Heilongjiang Province under Grant(JQ 2021C005);Guangdong Provincial Natural Science Foundation under Grant(2017A030310367)。
Bovine hepacivirus(BovHepV)is a novel virus that was recently discovered in Ghana and Germany in 2015.Until now,this virus has been identified in cattle population worldwide and is classified into subtypes A-G.To full...
funded by the Academic Promotion Programme of Shandong First Medical University(2019QL006);the Open Research Fund Program of CAS Key Laboratory of Special Pathogens and Biosafety,Wuhan Institute of Virology(Grant No.2021SPCAS002);W.S.was supported by the Taishan Scholars program of Shandong Province。
Dear Editor,Hepaciviruses,members of the family Flaviviridae,are enveloped viruses containing a single-stranded positive-sense RNA genome of approximately 8.9-10.5 kb in size(Simmonds et al.,2017).To date,15species(He...
supported by the National Natural Science Foundation of China(81290341);the Basic Research Project of Shenzhen Science and Technology Innovation Program(JCYJ20150402102519532)
Dear Editor,Hepatitis C virus (HCV) is a leading global cause of various liver diseases, including chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. The genome of HCV is monopartite, single-stranded, p...
Supported by Grants from the Study on Prevention and Control of Viral Hepatitis in the Key Program for Science and Technology Development of Hebei Province,No.10276102D
AIM: To construct a tricistronic hepatitis C virus (HCV) replicon with double internal ribosome entry sites (IRESes) of only 22 nucleotides for each, substituting the encephalomyocarditis virus (EMCV) IRESes, which ar...
AIM:The significance of hepatitis C virus (HCV) serum titers has been examined in several clinical situations. There is much evidence that patients with a lower viral load have better response rates to anti-viral ther...
AIM: To clarify the effect of SEN virus (SENV) infection on a combination therapy including interferon alfa (IFN-α) or pegylated-IFN with ribavirin in patients with chronic hepatitis and the effect of a combination t...
AIM:Hepatitis C virus(HCV)infection is very common among end-stage kidney disease patients on hemodialysis,but its natural history is not known. METHODS:In this study,189 dialysis patients(case) positive for HCV antib...
AIM:To test whether in vitro incubation of peripheral blood mononuclear cells (PBMC) with interferon (IFN) could efficiently decrease hepatitis C virus-RNA (HCV-RNA) amount and to analyze whether this effect was assoc...
the Universidad de Buenos Aires(SECyT-UBA,TB14);Consejo Nacional de Investigaciones Científicas y Técnicas(CONICET,PIP723);Agencia Nacional de Promoción Científica y Tecnológica(ANPCyT,PICT 01610);Ministerio de Salud Pǘblica de la Nación(Beca Carrillo-Oativia)
AIM: To analyze the molecular evolution of different viral genomic regions of HCV in an acute HCV infected patient chronically infected with HIV through a 42-month follow-up.METHODS: Serum samples of a chronically HIV...