Α-GLUCOSIDASE

作品数:97被引量:175H指数:6
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相关领域:医药卫生更多>>
相关作者:陈光英郑彩娟罗由萍周通肖音更多>>
相关机构:哈尔滨工业大学中国科学院大叶大学海南师范大学更多>>
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相关基金:国家自然科学基金广东省自然科学基金国家教育部博士点基金国家重点基础研究发展计划更多>>
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Inhibitory effect and mechanism of tannic acid against two starch digestive enzymes
《Food Quality and Safety》2024年第1期115-123,共9页钟毓秀 倪德让 杨玉波 李元一 王莉 田金虎 杨帆 叶兴乾 
the Institute of Science and Technology,Moutai Group(No.MTGF2021020),China.
Backgrounds:Tannic acid(TA),as a plant-derived phenolic substance,is involved in regulating the activity of starch digestive enzymes,but its underlying mechanism remains unclear.Methods and Results:In the present stud...
关键词:Tannic acid Α-AMYLASE Α-GLUCOSIDASE INHIBITION starch digestion. 
Surface engineering of carbon dots for highly sensitive α-glucosidase assay and inhibition evaluation被引量:1
《Chinese Chemical Letters》2024年第3期193-197,共5页Meijuan Liang Gege Song Yeqing Wan Yingying Chen Fuan Wang Xiaoqing Liu 
supported by National Natural Science Foundation of China(Nos.32202171,22274121 and 22274123)。
Monitoringα-glucosidase(α-Glu)activity is of great significance for the early diagnosis of typeⅡdiabetes.Here the blue fluorescent carbon dots(CDs)were integrated with two different recognizing molecules,β-cyclode...
关键词:Α-GLUCOSIDASE Carbon dots Fluorescent sensor INHIBITOR Β-CYCLODEXTRIN 
Screening,characterization of traceα-glucosidase inhibitors from the root of Pueraria lobata and evaluation of their hypoglycemic activity
《Food Bioscience》2023年第3期1405-1411,共7页Haiping Xiang Ping Xu Weiyi Wen Huiyun Qiu Chu Chu Qingsong Shao Shengqiang Tong 
financially supported by the National Natural Science Foundation of China(21978266);Natural Science Foundation of Zhejiang Province(LBY22H280004);Academy of Science&Tech-nology of Zhejiang University of Technology(KYY-HX-20210732,KYYHX-20210066,KYY-HX-20200221,KYY-HX-20190182).
Pueraria lobata(Willd.)Ohwi(Gegen)is a nutritious medicine food homology plant that has been recorded in many ancient remedies for diabetes.However,its hypoglycemic active components and related mechanisms have not be...
关键词:Pueraria lobata Liquid-liquid refined extraction High-resolution profiling α-Glucosidase inhibition 
Structural characterizations andα-glucosidase inhibitory activities of four Lepidium meyenii polysaccharides with different molecular weights
《Natural Products and Bioprospecting》2023年第1期568-576,共9页Luan Wen Zhou-Wei Wu Li-Wu Lin Abdulbaset Al-Romaima Xing-Rong Peng Ming-Hua Qiu 
the National Natural Science Foundation of China(No.31872675);the Cooperation Project with DR PLANT Company(2023).
Four polysaccharides(MCPa,MCPb,MCPc,MCPd)were obtained from Lepidium meyenii Walp.Their structures were characterized by chemical and instrumental methods including total sugar,uronic acid and protein content determi-...
关键词:Lepidium meyenii POLYSACCHARIDE Molecular weight Structural characterization α-Glucosidase inhibition 
In vitro bioaccessibility of phenolic compounds and alpha-glucosidase inhibition activity in yoghurts enriched with mango peel powder被引量:1
《Food Bioscience》2022年第6期456-464,共9页Hafza Fasiha Zahid Akhtar Ali Chaminda Senaka Ranadheera Zhongxiang Fang Frank R.Dunshea Said Ajlouni 
the financial assistance provided to H.F.Z.by the government of Pakistan.
This study investigated the potential health benefits and functional properties of mango peel powder(MPP)as a source of antioxidants and alpha-glucosidase inhibitors in yoghurts with probiotic bacteria.The study invol...
关键词:Mango peel powder fortified Probiotic yoghurts BIOACCESSIBILITY α-Glucosidase inhibition activity Antioxidant capacity 
New phenolic constituents obtained from Polygonum multiflorum被引量:10
《Chinese Herbal Medicines》2020年第3期342-346,共5页Jian-bo Yang Hua Sun Jie Ma Yun-fei Song Yue Liu Qi Wang Shuang-cheng Ma Xian-long Cheng Feng Wei 
The authors are grateful to the members of the analytical group of the State Key Laboratory of Bioactive Substances and Functions of Natural Medicines,Institute of Materia Medica,Chinese Academy of Medical Sciences(CAMS)and Peking Union Medical College,Beijing,China for the spectroscopic data measurements and bioactivity tests.This project was financially supported by the National Natural Science Foundation of China(Nos.81703665,81773874,81973476 and 81903807);the National Major Scientific and Technological Special Project for"Significant New Drugs Development"(2018ZX09735006).
Objective:To isolate the phenolic compounds obtained from the dried roots ofPolygonum multiflorum and investigate their pharmacological activities.Methods:The chemical constituents were isolated and purified by combin...
关键词:α-glucosidase inhibition hepatoprotective activity phenolic compounds polygonimitin E polygonimitin F Polygonum multiflorum Thunb 
Antidiabetic effect of Chrysophyllum albidum is mediated by enzyme inhibition and enhancement of glucose uptake via 3T3-L1 adipocytes and C2C12 myotubes
《Asian Pacific Journal of Tropical Biomedicine》2020年第9期387-396,共10页Benjamin Kingsley Harley Rita Akosua Dickson Isaac Kingsley Amponsah Robert A Ngala Dorice Berkoh Theophilus Christian Fleischer 
supported by some funds from KNUST Research Fund(KReF)
Objective:To investigate the in vivo and in vitro antidiabetic potential of Chrysophyllum albidum.Methods:The effects of oral treatment with hydro-ethanolic extract(125,250 and 500 mg/kg)of the stem bark of Chrysophyl...
关键词:ANTIDIABETIC C2C12 myotubes α-glucosidase inhibition α-amylase inhibition Glucose uptake Chrysophyllum albidum 
New octadecanoid derivatives from the seeds of Ipomoea nil
《Chinese Journal of Natural Medicines》2019年第4期303-307,共5页SONG Xiu-Qing ZHANG Jun-Sheng YU Shu-Juan YU Jin-Hai ZHANG Hua 
supported by the Natural Science Foundation of Shandong Province(No.JQ201721);the Young Taishan Scholars Program(No.tsqn20161037);the Director Foundation of XTIPC,CAS(No.2015RC015);Shandong Talents Team Cultivation Plan of University Preponderant Discipline(No.10027)。
Four new octadecanoid derivatives(1–4) including a pair of enantiomers(1/2), along with 12 known analogues(5–16), were isolated from the seeds of Ipomoea nil. Their structures were determined by detailed spectroscop...
关键词:Ipomoea nil Octadecanoid Fatty acid Natural enantiomer α-Glucosidase inhibition 
Total phenolic compounds,antioxidant potential and α-glucosidase inhibition by Tunisian Euphorbia paralias L.
《Journal of Coastal Life Medicine》2016年第8期628-633,共6页Malek Besbes Hlila Kaouther Majouli Fethia Harzallah Skhiri Hichem Ben Jannet Mahjoub Aouni Maha Mastouri Boulbaba Selmi 
Supported by the Ministry of High Education and Scientific Research,MHSSR of Tunisia(Grant No.11/TM06).
Objective:To examine the potential antioxidant and anti-α-glucosidase inhibitory activities of Tunisian Euphorbia paralias L.leaves and stems extracts and their composition of total polyphenol and flavonoids.Methods:...
关键词:Euphorbia paralias L. Polyphenolic compounds Antioxidant activity Anti-α-glucosidase activity 
α-Glucosidase Inhibition by New Schiff Base Complexes of Zn(II)
《Open Journal of Inorganic Chemistry》2016年第2期114-124,共11页Rie Miyazaki Hiroyuki Yasui Yutaka Yoshikawa 
There are many reports that divalent alkaline earth, first-row transition metals, and Zn(II) ions have α-glucosidase inhibitory effects. Cu(II) and Zn(II) ions, in particular, have strong α-glucosidase inhibitory ef...
关键词:α-Glucosidase Inhibitory Effect Zn(II) Complexes Schiff Bases Diabetes Mellitus 
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