ANTHRAQUINONES

作品数：35被引量：109H指数：6
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相关领域：医药卫生理学更多>>
相关作者：吴子斌王峥涛徐珞珊卢艳花屠鹏飞更多>>
相关机构：香港中文大学中国药科大学北京大学河南师范大学更多>>
相关期刊：《Chinese Herbal Medicines》《Chinese Journal of Integrative Medicine》《Chinese Journal of Natural Medicines》《World Journal of Gastroenterology》更多>>
相关基金：国家自然科学基金国家科技支撑计划俄罗斯基础研究基金更多>>
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Organ specific differences in alteration of aquaporin expression in rats treated with sennoside A,senna anthraquinones and rhubarb anthraquinones被引量：2
《中国药理学与毒理学杂志》2021年第10期772-773,共2页WANG Zhao-yang CHENG Ying QIAO Bo-ling 
OBJECTIVE Senna and rhubarb are classified as stimulative laxatives,and known to have similar effective constituents,the anthraquinones.Being protected by theβ-glucoside bond,the anthraquinones can reach the intestin...
关键词：senna anthraquinones rhubarb anthraquinones sennoside A LAXATIVE AQUAPORINS 
Animal models of cathartic colon被引量：3
《World Journal of Clinical Cases》2021年第6期1251-1258,共8页Yang-Yang Meng Qiao-Dong Li Ya Feng Jie Liu En-Kang Wang Linda Zhong Qiao-Li Sun Jian-Ye Yuan 
Supported by Xinglin Scholar,Xinglin Young Talent Program,No.RC-2017-02-07;Shanghai Three-year Action Plan for Accelerating the Development of Traditional Chinese Medicine,No.ZY(2018-2020)-CCCX-2002-01;and Research Fund of Longhua Hospital,No.2018YM05.
The incidence of cathartic colon has been increasing,but satisfactory treatments are still lacking.In order to study the pathological mechanisms of the disorder and identify effective treatment methods,researchers hav...
关键词：Cathartic colon Animal model LAXATIVE ANTHRAQUINONES DIPHENYLMETHANE CONSTIPATION 
Identification of the multiple bioactive derivatives and their endogenous molecular targets that may mediate the laxative effect of rhubarb in rats
《Journal of Traditional Chinese Medical Sciences》2020年第2期210-220,共11页Lei Xie Ying Wang Gan Luo Wenjuan Zhou Jiayan Miao Siqi Tang Qin Jiang Yage Guan Xiaoyan Gao 
the National Natural Science Foundation of China(81673562 and 81973467);the Fundamental Research Funds for the Central Universities of China(2020-JYB-ZDGG-033).
Objective:To determine the mechanism of the laxative effect of rhubarb(Rheum tanguticum Maxim.ex Balf.)in rats using a combined bioinformatic and in vivo approach.Methods:Substances derived from rhubarb that are prese...
关键词：RHUBARB LAXATIVE ANTHRAQUINONES Anthrones C-KIT AQUAPORIN-3 
In vitro study of the nephrotoxicity of total Dahuang(Radix Et Rhizoma Rhei Palmati) anthraquinones and emodin in monolayer human proximal tubular epithelial cells cultured in a transwell chamber被引量：3
《Journal of Traditional Chinese Medicine》2019年第5期609-623,共15页Cao Chunyu Hui Lianqiang Li Chun Yang Yifei Zhang Jiyuan Liu Ting Hao Ran Zhang Yi 
Supported by the Central Public Welfare Research Institutes Foundation-funded Project:A new research of renal toxicity early detection of Chinese medicine(ZZ0908035);Establishment of HK-2 cell monolayer model of human proximal renal tubular epithelial cells(ZXKT15022);Bioactivity based quality control for Chinese herbal medicine using Rhubarb as model system(GH2017-01-02);Natural Science Foundation-funded Project:Study on the bacterial endotoxin detection method of traditional Chinese medicine injections(90709043)
OBJECTIVE: To examine changes in the morphology and physiological functions of human proximal tubular epithelial cells (HK-2 cells) caused by total Dahuang (Radix Et Rhizoma Rhei Palmati) anthraquinones (TDA) and emod...
关键词：ANTHRAQUINONES RHEUM EMODIN NEPHROTOXICITY Human proximal tubular epithelial cell TRANSWELL CHAMBER 
Antioxidant xanthones and anthraquinones isolated from a marine-derived fungus Aspergillus versicolor被引量：5
《Chinese Journal of Natural Medicines》2018年第3期219-224,共6页WU Ze-Hong LIU Dong XU Ying CHEN Jian-Liang LIN Wen-Han 
supported by the Knowledge Innovation Program of Shenzhen(JCYJ20160428181415376 andJCYJ20150529153646078)
Chemical examination of an EtOAc extract of cultured Aspergillus versicolor fungus from deep-sea sediments resulted in the isolation of four xanthones, eight anthraquinones and five alkaloids, including a new xanthone...
关键词：Aspergillus versicolor XANTHONES ANTHRAQUINONES Antioxidant activity CYTOTOXICITY 
An Integrated Study for the Utilization of Anthraquinone Compounds Extract“Heshouwu”In vivo and their Comparative Metabolism in Liver Microsomes Using UPLC-ESI-Q-TOF/MS^(n)被引量：1
《World Journal of Traditional Chinese Medicine》2018年第1期21-27,共7页Sha Chen Hong-Yu Ma Zhe Deng Jun Zhang Jin-Tang Cheng Chang Chen An Liu 
financial support from the Major Scientific and Technological Special Project for"Significant New Drugs Creation"(No.2014ZX09304307)
Objective: Anthraquinone(AQ), a major bioactive component of the traditional Chinese medicine He ShouW u, has widespread applications in industry and medicine. The objective of the current study is to explore the diff...
关键词：ANTHRAQUINONES liver microsomes UPLC-QqQ-MS/MS UPLC-Q-TOF/MS 
Simultaneous Determination of 10 Anthraquinones in Rhubarb Based on HPLC-Q-HR/MS被引量：4
《Chinese Herbal Medicines》2017年第4期388-395,共8页Su-xiang Feng Meng-meng Li Di Zhao Xian-he Li Lei Zhang Zhe Wang Ning-ning Gao 
National Natural Science Foundation of China(No.81274179)
Objective To develop a simple, sensitive, and precise method for simultaneous determination of 10 anthraquinones in Rhubarb. Methods HPLC-Q-HR/MS was employed for simultaneous quantification of free anthraquinones（al...
关键词：Anthraquinones HPLC-Q-HR/MS quality control quantitative analysis Rhubarb 
Bidirectional solid fermentation using Trametes robiniophila Murr. For enhancing efficacy and reducing toxicity of rhubarb (Rheum palmatum L.)被引量：5
《Journal of Traditional Chinese Medical Sciences》2017年第3期306-313,共8页Yancong Zhang Li Zhou Weiwei Ma Xiaosa Shi Hongmei Zhang Xinyuan Shi 
Objective:To investigate the potential of bidirectional solid fermentation of rhubarb (Rheum palmatum L.) for reducing its toxicity and enhancing its medicinal efficacy.Methods:The fungus Trametes robiniophila Murr.wa...
关键词：RHUBARB TRAMETES robiniophila Murr. BIDIRECTIONAL solid FERMENTATION ANTHRAQUINONES Cancer inhibition 
Rapid Determination of Total Content of Five Major Anthraquinones in Rhei Radix et Rhizoma by NIR Spectroscopy被引量：3
《Chinese Herbal Medicines》2017年第3期250-257,共8页Hao Zhan Jing Fang Hong-wei Wu Hong-jun Yang Hua Li Zhu-ju Wang Bin Yang Li-ying Tang Mei-hong Fu 
Special Fund of the National Bureau of TCM(No.201407003)
Objective To establish a new method with near-infrared（NIR） spectroscopy to determine the total content of emodin, chrysophanol, rhein, aloeemodin, and physcion. NIR was used in this study to provide rapid and nonde...
关键词：near-infrared spectroscopy partial least squares quality control rapid determination Rhei Radix et Rhizoma 
Phenanthrenes,anthraquinones,and phenolic constituents from Sinomenium acutum被引量：6
《Journal of Chinese Pharmaceutical Sciences》2017年第6期440-446,共7页吕海宁 赵明波 姜勇 屠鹏飞 
National Natural Sciences Foundation of Chin(NS FC;Grant Nos.81222051 and 81473106);National Key Technology R&D Program"New Drug Innovation"of China(Gran No s.2012ZX09301002-002-002 and 2012ZX09304-005)
A phytochemical investigation on the stems and rhizomes of Sinomenium acutum led to the isolation of 19 compounds, including three phenanthrenes, six anthraquinones, and ten phenolic derivatives. The structures of the...
关键词：Sinomenium acutum PHENANTHRENES ANTHRAQUINONES Phenolic constituents 
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