云南高校图书馆联盟文献共享服务平台- MACROLIDE

MACROLIDE: 作品数：32被引量：76H指数：4; 导出分析报告; 相关领域：医药卫生理学更多>>; 相关作者：夏曦李少丽李建成丁双阳江海洋更多>>; 相关机构：中国农业大学首都儿科研究所中国科学院更多>>; 相关期刊：《Acta Pharmacologica Sinica》《Chinese Medical Journal》《Advances in Microbiology》《World Journal of Pediatrics》更多>>; 相关基金：国家自然科学基金北京市自然科学基金“十一五”国家科技支撑计划The Royal Society更多>>

A Modular Synthesis of Antitumor Macrolide (-)-Lasonolide A被引量：1: 《Chinese Journal of Chemistry》2020年第7期725-736,共12页Lin Yang Zuming Lin Kuan Zheng Luyao Kong Ran Hong; the Drug Innovation Major Project(2018ZX09711001-005);the National Natural Science Foundation of China(91856202);the National Key R&D Program of China(2019YFA09005000);the Strategic Priority Research Program(XDB20000000);the Key Research Program of Frontier Sciences(QYZDYSSWSLH026)of the Chinese Academy of Sciences is highly appreciated.We also thank Jie Sun(SIOC,CAS)for the X-ray analysis.; Lasonolide A was identified as a potent antitumor macrolide towards various cancer cell lines.The two tetrahydropyrans bearing multiple stereogenic centers as well as the polyvene linkage attracted a dozen synthetic r...; 关键词：ALDEHYDES LINKAGE REAGENT

Alkaloids from the endophytic fungus Penicillium brefeldianum and their cytotoxic activities被引量：4: 《Chinese Chemical Letters》2017年第6期1194-1199,共6页Na Gao Zhi-Chun Shang Pei Yu Jie Luo Kai-Li Jian Ling-Yi Kong Ming-Hua Yang; funded by the National Natural Science Foundation of China(No.81503218);the Program for Changjiang Scholars and Innovative Research Team in University(No.IRT_15R63);the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD);the Fundamental Research Funds for the Central Universities(No.2016ZZD010); One new indoloditerpene,6,7-dehydropaxilline（1）,one new indole-diketopiperazine,spirotryprostatin F（2）,and one new 13-membered macrolide,N-demethylmelearoride A（3）,as well as 8 known alkaloids（4-11）,were isola...; 关键词：Penicillium brefeldianum Alkaloids Indoloditerpene Indole-diketopiperazine 13-Membered macrolide Cytotoxicities

Efficient Total Synthesis of （S）-Dihydroresorcylide, a Bioactive Twelve-Membered Macrolide被引量：1: 《Chinese Journal of Chemistry》2013年第3期339-343,共5页Li Zhang Wenquan Ma Lili Xu Fei Deng Yuewei Guo; This research work was financially supported by the Natural Science Foundation of China （Nos. 21021063, 81273430）, the National Marine ＂863＂ Project （Nos. 2011AA09070102 and 2013AA092902） and the SKLDR/SIMM Projects （No. SIMM1203ZZ-03）. We also thank Professor Minghua Xu （SIMM-CAS） for helpful discussion in preparation of this manuscript.; The efficient synthesis of （S）-dihydroresorcylide （la） along with trans-resorcylide dimethyl ether （2b）, was achieved in linear 9 steps from commercially available orcinol monohydrate （6） with esterification, ...; 关键词：dihydroresorcylide trans-resorcylide dimethyl ether ring-closing metathesis （RCM） carbonylation total synthesis

Antifungalmycin,an antifungal macrolide from Streptomyces padanus 702被引量：1: 《Natural Products and Bioprospecting》2012年第1期41-45,共5页Yi-Fen WANG Sai-Jin WEI Zhi-Ping ZHANG Tong-He ZHAN Guo-Quan TU; Two polyene macrolide antibiotics:antifungalmycin(1)and fungichromin(2)were isolated from the culture mycelia of Streptomyces padanus 702 via bioactivity-guided fractionation using various chromatographic procedures.T...; 关键词：antifungalmycin Streptomyces padanus 702 polyene macrolide BIOCONTROL antifungal activity PHYTOPATHOGEN

5′-Hydroxyzearalenol,a new β-resorcylic macrolide from Fusarium sp. 05ABR26被引量：1: 《Chinese Chemical Letters》2008年第9期1089-1092,共4页Ling Ling Zhao Yue Gai Hisayoshi Kobayashi Chang Qi Hu Hui Ping Zhang; the National Natural Science Foundation(No.30371680)of the People's Republic of China.; A new β-resorcylic macrolide, 5＇-hydroxyzearalenol （1）, was isolated from the culture broth of a marine-derived fungus Fusarium sp. 05ABR26. Three known compounds, zearalenone （2）, 8＇-hydroxyzearalenone （3） a...; 关键词：5＇-Hydroxyzearalenol Fusarium sp. X-ray diffraction data Pyricularia oryzae

Synthesis of novel 15-membered macrolide derivatives被引量：2: 《Chinese Chemical Letters》2008年第4期409-411,共3页Rui Qing Xian Shu Tao Ma Bo Jiao; supported by NNSFC(No.20372043),Shandong Science and Technology Promotion Project(No.2005GG3202098);Natural Science Foundation of Shandong Province(No.Y2006C31).; In order to develop new antibiotics effective against resistant bacteria,a series of novel 15-membered macrolide derivatives were designed and synthesized by the modification of hydroxyl groups at C-11,C-12 and C-4＂ ...; 关键词：MACROLIDE Azithromycin derivatives SYNTHESIS 4＂-Carbamate derivatives

Synthesis of derivatives of imidazo[4,5-b]pyridine:Novel sulfur contained side chains for macrolide antibiotics被引量：2: 《Chinese Chemical Letters》2008年第1期1-4,共4页Lu Liu Peng Xu Liang Zhou Ping Sheng Lei; Finacial support of this research by the National Natural Science Foundation of China （No. 30572275）；Natural Science Foundation of Beijing （No. 7062047） are gratefully acknowledged by the authors.; Two series of novel derivatives of imidazo[4,5-b]pyridine were synthesized. These compounds could be used as side chains of semisynthesised ketolide antibiotics. The side chains have free amine group which can attache...; 关键词：MACROLIDE Heterarylalkyl sulfur contained side chain Imidazo[4 5-b]pyridine Synthesis HMBC

Synthesis of 12-alkoxycarbonylmethylene-1,15-pentadecanolides: 《Chinese Chemical Letters》2007年第8期915-916,共2页Jian Jun Li Shu Hui Jin Xiao Mei Liang De Kai Yuan Dao Quan Wang; Six novel 12-alkoxycarbonylmethylene-1,15-pentadecanolides （3） were synthesized from 2-nitrocyclo-dodecanone by the Michael addition with acrolein followed by ring enlargement, Nef reaction and Wittig-Homer reaction...; 关键词：12-Alkoxycarbonylmethylene-1 15-pentadecanolide MACROLIDE Acrylic ester Wittig-Horner reaction Fungicidal actictity

A Novel Oxidative N-Demethylation of 12-Membered Macrolide with Lead Tetraacetate: 《Chinese Chemical Letters》2006年第1期9-11,共3页Wei Ge ZHANG Ying Hua JIN Ping QI Kai BAO Jin Guang LIN Nai Li WANG Xin Shen YAO; Reaction of 12-membered macrolide 1 with lead tetraacetate in dichloromethane afforded an unexpected, novel oxidative N-demethyl product 3.; 关键词：Oxidative N-demethylation 12-membered macrolide lead tetraacetate.

Partial Synthesis of Macrolide Alkaloid Euonine: 《Chinese Chemical Letters》1998年第10期927-928,共2页Yuan Chao LI Shan Hao JIANG Xiao Yi WANG (Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 200031 Department of Environmental Chemistry and Engineering, Beijing Polytechnic University,Beijing, 100022); The macrolide alkaloid euonine 1 with pharmacologic activity was prepared from the alkaloid wilforgine 2. Their structures were confirmed by IR, NMR, MS and optical rotation.; 关键词：TRIPTERYGIUM macrolide alkaloid wilforgin euonine

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