Background:immune checkpoint inhibitors(ICIs)have revolutionized the treatment of metastatic urothelial carcinoma(mUC),significantly improving survival outcomes.However,a subset of patients do not respond to ICIs,prom...
This article relates to the discussion of a recent study published by Wohl et al.Primary sclerosing cholangitis(PSC)is a chronic inflammatory liver disease that affects the intra-and extrahepatic bile ducts and is str...
BACKGROUND Addressing oculoplastic conditions in the preoperative period ensures both the safety and functional success of any ophthalmic procedure.Some oculoplastic conditions,like nasolacrimal duct obstruction,have ...
supported by the National Natural Science Foundation of China(92061201,92356304,and 22271258);the Zhongyuan Thousand Talents(Zhongyuan Scholars)Program of Henan Province(234000510007),and Zhengzhou University;China National Postdoctoral Program for Innovative Talents(BX20230329)。
Owing to their inherently excellent geometric structure[1-3]and applications in catalysis,luminescence,and biology[4-6],as well as their importance in gaining insights into the embryonic period of metal nanoparticles,...
supported by Sichuan Province Medical Young Innovative Research Project Program(No.Q23041).
To the Editor:Based on a recent study examining the burden of digestive diseases in China and its provinces from 1990 to 2019,esophageal cancer ranks as the third leading cause of death among neoplastic digestive dise...
Supported by Grant Agency of the Ministry of Health of the Czech Republic,No.NV17-31538A;Grant Agency of the Czech Republic No.20-16520Y and No.21-21736S;Ministry of Education,Youth and Sports of the Czech Republic Project,No.LX22NPO05102.
BACKGROUND Ulcerative colitis(UC)with concomitant primary sclerosing cholangitis(PSC)represents a distinct disease entity(PSC-UC).Mayo endoscopic subscore(MES)is a standard tool for assessing disease activity in UC bu...
To the Editor:Mantle cell lymphoma(MCL)is a rare subgroup of B-cell nonHodgkin’s lymphoma(NHL)that occurs in approximately 6%of NHL patients.Chronic hepatitis and cirrhosis may promote hepatocellular carcinoma(HCC)de...
BACKGROUND Ischemic stroke is a rare event associated with an elevated risk of blood clot formation owing to an underlying malignancy.Herein,we present a case of ovarian carcinoma that led to cerebral infarction.CASE ...
BACKGROUND Mast cell leukemia(MCL),a subtype of systemic mastocytosis(SM),is an extremely rare clinical entity characterized by a very poor prognosis.Chemotherapy,tyrosine kinase inhibitors,and allogeneic hematopoieti...
Supported by Wu Jieping Medical Foundation,No.320.6750.2022-20-25;and Chongqing Health Commission,No.[2020]68.
BACKGROUND Epidermal growth factor receptor(EGFR)mutation and c-ros oncogene 1(ROS1)rearrangement are key genetic alterations and predictive tumor markers for non-small cell lung cancer(NSCLC)and are typically conside...