ELEMENE

作品数：19被引量：107H指数：6
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相关领域：医药卫生更多>>
相关作者：袁静顾振纶周文轩林吉惠钟伟健更多>>
相关机构：苏州医学院中山医科大学杭州师范大学杭州市肿瘤医院更多>>
相关期刊：《Chinese Journal of Cancer Research》《Cellular & Molecular Immunology》《Chinese Journal of Integrative Medicine》《International Journal of Ophthalmology(English edition)》更多>>
相关基金：国家自然科学基金更多>>
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Elemene Antitumor Drugs Development Based on "Molecular Compatibility Theory" and Clinical Application: A Retrospective and Prospective Outlook被引量：1
《Chinese Journal of Integrative Medicine》2024年第1期62-74,共13页JIANG Xiao-ying SHI Li-ping ZHU Jun-long BAI Ren-ren XIE Tian 
Elemene, derived from Curcuma wenyujin, one of the "8 famous genuine medicinal materials of Zhejiang province," exhibits remarkable antitumor activity. It has gained wide recognition in clinical practice for effective...
关键词：molecular compatibility theory Chinese integrative medicine ELEMENE antitumor activity drug delivery structural modification 
Elemene sensitizes pancreatic cancer cells to bortezomib by enhancing proteasome inhibition via molecular patch mechanism被引量：2
《Signal Transduction and Targeted Therapy》2023年第3期924-927,共4页Shurong Hou Zhenzhen Li Xiaoling Chen Wenxin Wang Ting Duan Louis Scampavia Yaxia Yuan Timothy P.Spicer Xiabin Chen Tian Xie 
This work was supported by the grant from the National Natural Science Foundation of China(Grant No.81903108 to S.H.);the Key Project of Zhejiang Ministry of Science and Technology(Grant No.2021C03087 to T.X.);the Key Project of Hangzhou Ministry of Science and Technology(Grant No.20212013B03 to T.X.).We thank Pierre Baillargeon and Lina Deluca at Scripps for their help with compound management,and Shujuan Zhao at Hangzhou Normal University for proteomics analysis.
Dear Editor,Pancreatic cancer*is one of the deadliest cancers,with an overall 5-year survival rate of less than 10%unchanged over the last 40 years.Approximately 80-85%of patients are diagnosed as advanced stage,which...
关键词：DRUGS CHEMOTHERAPY CURATIVE 
Real world analysis on renal impairment of elemene emulsion injection based on propensity score matching
《Journal of Hainan Medical University》2022年第18期33-37,共5页LEI Chao ZHAO Xiao-xiao YU Xiao-kang XIE Yan-ming WANG Zhi-fei 
Key project of Science and Technology Innovation Project of China Academy of Chinese Medical Sciences(NO.CI2021A00702);the National Key Research and Development Program(NO.2018YFC1707410)。
Objective:To explore the main factors of renal function injury caused by the combination of elemene emulsion injection in the real world.Methods:Based on the hospital information system medical database constructed by...
关键词：Real world Elemene emulsion injection Renal impairment Propensity score 
Analysis on Clinical Characteristics and Combination Medications of Elemene Injection in the Treatment of Esophageal Cancer in Real World Research
《World Journal of Integrated Traditional and Western Medicine》2022年第3期1-8,共8页SHI Pu-wen ZHAO Xiao-xiao XIE Yan-ming YU Xiao-kang 
Science and technology innovation project of China Academy of Chinese Medical Sciences(ci2021a00702);[approval:National key R&D plan"demonstration study on evidence-based evaluation and effect mechanism of ten large varieties of Chinese patent medicines and classic famous prescriptions in the treatment of major diseases after listing"(2018yfc1707400)]。
Objective:To explore the clinical characteristics of Elemene Injection in the treatment of patients with esophageal cancer.Methods:A total of 310 patients diagnosed with esophageal cancer from the Hoptital Information...
关键词：Real world research Combination medications Elemene Injeciton Esophageal cancer patients Clinical characteristics 
Elemene Emulsion Injection Administration Reduces Neuropathic Pain by Inhibiting Astrocytic NDRG2 Expression within Spinal Dorsal Horn被引量：5
《Chinese Journal of Integrative Medicine》2021年第12期912-918,共7页MA Li-tian BAI Yang LI Jie QIAO Yu LIU Yang ZHENG Jin 
the Science and Technology Co-ordination Innovation Project Plan of Shaanxi Province(No.2016KTCL03-16)。
Objective To investigate the mechanisms underlying elemene-induced analgesia in rats with spared nerve injury(SNI).Methods Sixty-five rats were equally divided into 5 groups using a random number table:naive group,sha...
关键词：elemene emulsion injection ASTROCYTE NMYC downstream-regulated gene 2 
Efficacy and safety of elemene combined with SOX in the treatment of advanced metastatic gastric cancer
《Journal of Hainan Medical University》2020年第2期36-41,共6页Ye Qian Yan Zhang Xiao-Min Lu Ming-Hao Ji 
Wu Jieping medical foundation project (320.3750.18075)
Objective: To explore the therapeutic effect of elemene combined with S-1 / oxaliplatin (SOX) in the treatment of advanced metastatic gastric cancer, and to analyze and evaluate the safety of the chemotherapy, so as t...
关键词：ELEMENE tegio OXALIPLATIN advanced metastatic gastric cancer EFFICACY safety 
Effect of bronchial arterial infusion chemotherapy combined with elemene on the malignant lesion molecules and systemic immune response in patients with advanced lung cancer被引量：1
《Journal of Hainan Medical University》2017年第4期19-22,共4页Hao-Wen Huang Xuan Wu Hai-Dong Pan Ai-Fen Liang 
Objective:To study the effect of bronchial arterial infusion chemotherapy combined with elemene on the malignant lesion molecules and systemic immune response in patients with advanced lung cancer.Methods:A total of 7...
关键词：Lung cancer ELEMENE BRONCHIAL arterial INFUSION chemotherapy Invasion Proliferation 
The reversal of antineoplastic drug resistance in cancer cells by B-elemene被引量：11
《Chinese Journal of Cancer》2015年第11期488-495,共8页Guan-Nan Zhang Charles R.Ashby Jr. Yun-Kai Zhang Zhe-Sheng Chen Huiqin Guo 
supported by St.John’s University Research Seed Grant (No. 579-1110-7002) to Zhe-Sheng Chen
Multidrug resistance(MDR), deined as the resistance of cancer cells to compounds with diverse structures and mechanisms of actions, signiicantly limits the eicacy of antitumor drugs. A major mechanism that mediates MD...
关键词：Rhizoma zedoariae  B-Elemene Multidrug resistance 
The clinical research of elemene emulsion combined with FOLFOX4 regimen in the treatment of advanced gastric carcinoma被引量：1
《The Chinese-German Journal of Clinical Oncology》2012年第6期336-339,共4页Yanzhi Bi Dongxiang Zeng Yang Ling 
Objective:The aim of this study was to observe the effects and adverse reactions of elemene emulsion added to the chemotherapy in the treatment of advanced gastric carcinoma (AGC).Methods:Forty-nine patients were divi...
关键词：elemene emulsion advanced gastric carcinoma （AGC） FOLFOX4 regimen 
Mechanisms of inhibition of elemene on human lens epithelial cell proliferation in vitro被引量：4
《International Journal of Ophthalmology(English edition)》2011年第3期255-258,共4页Yan-Hong Hu, Bu-Yuan Hou 
Youth Foundation of Fujian Scientific Committee, China (No.2008F3050)
AIM: To study the effects of elemene (Ele) on proliferation and cell cycle of human lens epithelial cells 63 (HLE-B3) and the mechanisms of its signal transduction. METHODS: Recombinant human basic fibroblast growth f...
关键词：lens epithelial cell cell culture AFTER-CATARACT ELEMENE 
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