PRUNELLA

作品数:18被引量:64H指数:4
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相关领域:医药卫生生物学更多>>
相关作者:杨哲赵敏杨杏芬张文娟谭剑斌更多>>
相关机构:广东省疾病预防控制中心中山大学暨南大学陕西理工大学更多>>
相关期刊:《Journal of Hainan Medical University》《China Medical Abstracts(Internal Medicine)》《Journal of Chinese Pharmaceutical Sciences》《天水师范学院学报》更多>>
相关基金:国家自然科学基金广东省科技计划工业攻关项目国家高技术研究发展计划广东省自然科学基金更多>>
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Exploring the antihypertensive mechanism of Prunella vulgaris through integrated network pharmacology analysis
《Journal of Chinese Pharmaceutical Sciences》2024年第11期1068-1081,共14页Na Sun Yujing Wang Caihong Zhou Huanhuan Kang Shuo Ma Yu Zhang Yuhan Yuan Xin Zhang Linxuan Jin Wenqian Li Xinru Wu Penghua Shu 
National Natural Science Foundation of China(Grant No.21702178);Training Plan of Young Backbone Teachers in Universities of Henan Province(Grant No.2021GGJS144);Key Scientific Research Program in Universities of Henan Province(Grant No.22A350009 and 23A350012);National Undergraduate Training Program for Innovation and Entrepreneurship(Grant No.202410480007 and 202310480020);Undergraduate Training Program for Innovation and Entrepreneurship of Henan Province(Grant No.202210480020 and 202210480021);Scientific Research Innovation Team of Xuchang University(Grant No.2022CXTD007);Horizontal Cooperation Project(Grant No.2023HX181);Undergraduate Training Program for Innovation and Entrepreneurship of Xuchang University(Grant No.X202210480016)。
Prunella vulgaris,a traditional Chinese medicine(TCM),exerts a significant hypotensive effect,particularly in managing various forms of hypertension.Nonetheless,the precise antihypertensive constituents and their resp...
关键词:Prunella vulgaris L. Anti-hypertension Traditional Chinese medicine targets Natural active ingredients 
Effects of a long-term administration of aqueous extract of Prunella vulgaris L.on survival,spontaneous thyroid carcinoma and neoplastic C-cell hyperplasia in rats
《China Medical Abstracts(Internal Medicine)》2023年第3期136-136,共1页宋佳 
Objective To investigate the effects of an aqueous extract of Prunella vulgaris L.(PV)on survival,spontaneous thyroid carcinoma and its preneoplastic lesion in rats.Methods A total of 552 Wistar rats were randomly ass...
关键词:NEOPLASTIC RATS SPONTANEOUS 
Advances in the Intervention of Prunella Spica Capsules on Postoperative Recurrence of Nodular Goiter
《Medicinal Plant》2023年第4期119-122,共4页Chuanwen SHI Xiaogong YOU Qingyun LI Honglei YANG Yulin XU 
Supported by the Key Project of Teaching Reform Research of Taishan Vocational College of Nursing(202307).
As important drugs for the treatment of nodular goiter(NG),Prunella Spica preparations are widely used clinically,and have a significant effect on NG.Various active ingredients in the preparations intervene in the for...
关键词:Prunella Spica capsules Nodular goiter Postoperative recurrence INTERVENTION 
The mechanism of Astragalus-Prunella vulgaris in the treatment of diabetic cardiomyopathy based on network pharmacology and molecular docking
《Journal of Hainan Medical University》2022年第20期25-35,共11页LIU Li-ying HUANG Ju-kai LI Gao-biao ZHANG Li YANG Xiao-hui 
National Natural Science Foundation of China(No.81974541)。
Objective:To study the main chemical components and mechanism of Astragalus and Prunella vulgaris in the treatment of diabetes cardiomyopathy(DCM)based on network pharmacology and in vitro experiments.Methods:The main...
关键词:ASTRAGALUS PRUNELLA Diabetic cardiomyopathy Network pharmacology Molecular docking 
Emerging therapeutic role of Prunella vulgaris in thyroid disease被引量:2
《Chinese Herbal Medicines》2022年第3期403-413,共11页Wen Zhang Qimuge Wuhan Meiri Na Riba Hu Qier Mu Xilinqiqige Bao 
financially supported by the Inner Mongolia Natural Science Foundation Project (2020MS08203);the New drug Research&Development Projects of the Inner Mongolia Medical Research Institute (YJS20186 and 2016YJS21)
Thyroid disease is characterized by unusual levels of thyroid hormones,which results in either hyperthyroidism or hypothyroidism.The pathology of a particular type or stage of thyroid disease is very complicated,and a...
关键词:APOPTOSIS herbal recipes Prunella vulgaris L. thyroid disease TNF-α 
A Metabolomics Study of the Volatile Oil from Prunella vulgaris L.on Pelvic Inflammatory Disease被引量:1
《Digital Chinese Medicine》2020年第3期213-221,共9页DENG Jing SU Qian LIN Xiu-Lian LIN Yan LI Ya-Mei LIN Li-Mei LIAO Duan-Fang XIA Bo-Hou 
We thank for the funding support from the National Natural Science Foundation of China(No.81503041);Natural Science Foundation of Hunan Province(No.2017JJ4045);Changsha Science and Technology Project(No.kq1701073).
Objective Pelvic inflammatory disease(PID)is one of the most common gynaecological diseases.Here,this thesis aims to investigate the therapeutic effects of Prunella vulgaris L.oil on the PID by using metabolomics base...
关键词:Pelvic inflammatory disease(PID) Metabolomics method Gas chromatography-mass spectrometry(GCMS) Prunella vulgaris L.oil Random forests 
Prunella vulgaris Polysaccharide Inhibits Growth and Migration of Breast Carcinoma-Associated Fibroblasts by Suppressing Expression of Basic Fibroblast Growth Factor被引量:16
《Chinese Journal of Integrative Medicine》2020年第4期270-276,共7页HAO Jian DING Xiu-li YANG Xue WU Xiong-zhi 
Supported by the National Science Foundation of China(No.81173376);New Century Excellent Talent(No.NCET-11-1068)。
Objective:To study the effects of Prunella vulgaris polysaccharide(PVP)on human breast carcinoma-associated fibroblasts(CAFs).Method:Cell viability was detected by 3-[4,5-dimethylthiazol-2-yl]-2,5-(3-carboxymethoxyphe...
关键词:PRUNELLA VULGARIS POLYSACCHARIDE carci no ma-associated fibroblasts basic FIBROBLAST GROWTH factor SKBr-3 Chinese medicine 
夏枯草诱导人甲状腺乳头状癌细胞K1增殖和凋亡的影响及其作用机制被引量:20
《现代生物医学进展》2017年第13期2401-2406,共6页熊燚 赵敏 谭剑斌 吴仕漩 杨哲 张文娟 杨杏芬 
国家科技部"863"项目(2010AA023001);广东省自然科学基金项目(S2013010013289);广东省科技计划项目(2013B010404033);广州市科技计划项目(201300000161);广东省中药局课题(20132108;20121275)
目的:探索夏枯草对人甲状腺乳头状癌细胞(K1)增殖和诱导K1细胞凋亡的影响及其可能的作用机制。方法:采用MTT比色法测定2~200 mg/mL夏枯草作用24 h对K1细胞增殖的影响;采用Hoechst染色法和流式细胞术(Annexin V-FITC/PI联合标记)观察0.3...
关键词:夏枯草 人甲状腺乳头状癌细胞 凋亡 线粒体通路 PRUNELLA VULGARIS L. 
夏枯草总黄酮的抗氧化活性研究被引量:10
《湖北农业科学》2016年第9期2316-2318,2443,共4页曹小燕 杨海涛 
陕西省教育厅专项科研计划项目(2013JK0680);陕西理工学院2013年校级人才启动项目(SLGQD13-1)
采用分光光度法研究了夏枯草(Prunella vulgaris L.)总黄酮的抗氧化活性。结果表明,在浓度为0.12 mg/m L时,对羟基自由基(·OH)清除率达到96%;在浓度为0.004 mg/m L时,对ABTS自由基正离子(ABTS+·)的清除率达到99%;在浓度为0.01 mg/m L...
关键词:夏枯草(Prunella VULGARIS L.) 总黄酮 抗氧化 清除 
Orally administered extract from Prunella vulgaris attenuates spontaneous colitis in mdr1a^(-/-) mice被引量:8
《World Journal of Gastrointestinal Pharmacology and Therapeutics》2015年第4期223-237,共15页Kelley MK Haarberg Meghan J Wymore Brand Anne-Marie C Overstreet Catherine C Hauck Patricia A Murphy Jesse M Hostetter Amanda E Ramer-Tait Michael J Wannemuehler 
The award from NIH(9P50 AT004155-06)
AIM: To investigate the ability of a Prunella vulgaris(P. vulgaris) ethanolic extract to attenuate spontaneous typhlocolitis in mdr1a-/- mice. METHODS: Vehicle(5% ethanol) or P. vulgaris ethanolic extract(2.4 mg/d) we...
关键词:PRUNELLA VULGARIS SPONTANEOUS COLITIS INFLAMMATORY 
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