CONUS

作品数：26被引量：53H指数：4
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相关领域：生物学医药卫生更多>>
相关作者：周晓薇戴秋云刘凤云黄培堂李晓玲更多>>
相关机构：军事医学科学院汕头市中心医院汕头大学复旦大学更多>>
相关期刊：《World Journal of Clinical Cases》《Science Bulletin》《Agricultural Biotechnology》《生态学报》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金国家高技术研究发展计划更多>>
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Mass Spectrometry-based Sequencing of Venom Peptides(Conotoxins)from Vermivorous Cone Snail,Conus Loroisii:Toxicity of its Natural Venom
《Journal of Marine Science》2021年第1期39-47,共9页Humaira Saleh Syed Rishimol R Arun Kumar J M Masilamani Selvam Rajesh R P 
Conus loroisii is a marine vermivorous snail found profusely in the southern seas of India.They harbor several toxic peptide components commonly called as‘conotoxins’.In this study,we have identified and sequenced f...
关键词：Conus loroisii CONOTOXINS TOXICITY Mass spectrometry 
Isolation and characterization of five novel mini-M conotoxins from the venom of mollusk-hunter snail Conus bandanus
《Asian Pacific Journal of Tropical Biomedicine》2020年第8期343-352,共10页Nguyen Bao Jean-Pière LE CAER Phan Thi Khanh Vinh 
funded by Vietnam National Foundation for Science and Technology Development(NAFOSTED)under grant number 106-NN.02-2015.14
Objective:To determine the new M-superfamily conotoxins from molluscivorous snail Conus bandanus in Vietnam.Methods:Conus bandanus venom was fractionated and purified on HPLC system with an analytical reversed-phase C...
关键词：Mini-M conotoxin Conus bandanus Cone snail venom 
Chemical synthesis and characterization of two α4/7-conotoxins被引量：2
《Acta Biochimica et Biophysica Sinica》2010年第10期745-753,共9页Can Peng Weihua Chen Tanya Sanders Geoffrey Chew Jing Liu Edward Hawrot Chengwu Chi 
α-Conotoxins are small disulfide-constrained peptides that act as potent and selective antagonists on specific subtypes of nicotinic acetylcholine receptors （nAChRs）. We previously cloned two α-conotoxins, Mrl.1 f...
关键词：CONUS α4/7-conotoxin nicotinic acetylcholinereceptor ANALGESIC 
cDNA cloning of conotoxins with framework XII from several Conus species被引量：4
《Acta Biochimica et Biophysica Sinica》2010年第9期656-661,共6页Zhuguo Liu Zheng Yu Na Liu Chongjia Zhao Jie Hu Qiuyun Dai 
In our efforts for cloning novel I2-superfamily conotoxins using the signal peptide sequence, we identified a novel conotoxin Lt12.4 from Conus litteratus. This gene has a framework XII （-C-C-C-C-CC-C-C-）, which is ...
关键词：framework XII CONOPEPTIDES cDNA clone CONUS E-conotoxins 
Two Potent α3/5 Conotoxins from Piscivorous Conus achatinus被引量：5
《Acta Biochimica et Biophysica Sinica》2007年第6期438-444,共7页Li LIU Geoffrey CHEW Edward HAWROT Chengwu CHI Chunguang WANG 
Every cone snail produces a mixture of different conotoxins and secretes them to immobilize their prey and predators, α3/5 Conotoxins, isolated from fish-hunting cone snails, target muscle nicotinic acetylcholine rec...
关键词：cone snail α3/5 conotoxin disulfide bond nicotinic acetylcholine receptor 
cDNA Cloning of Two Novel T-superfamily Conotoxins from Conus leopardus
《Acta Biochimica et Biophysica Sinica》2006年第4期287-291,共5页Wei-Hua CHEN Yu-Hong HAN Qi WANG Xiao-Wei MIAO Ling OU Xiao-Xia SHAO 
This work was supported by a grant from the National Natural Science Foundation of China (No.30170210)
The full-length cDNAs of two novel T-superfamily conotoxins, Lp5.1 and Lp5.2, were cloned from a vermivorous cone snail Conus leopardus using 3＇/5＇-rapid amplification of cDNA ends. The cDNA of Lp5.1 encodes a precu...
关键词：Conus leopardus T-superfamily CONOTOXIN cDNA cloning 
New O-superfamily conotoxins from Conus striatus inhabited near Chinese Hainan Island
《Chinese Science Bulletin》2000年第5期432-435,共4页Baisong Lu Fang Yu Jianhua Wang Siqing Zhao Dong Zhao Qiuyun Dai Peitang Huang Cuifen Huang 
Conotoxins are short peptide-toxins with specific targets and large diversity. They are usetul in analgesia, neuroprotection, detection of some kinds of deseases, and receptor and ion channel study. in order to explor...
关键词：CONOTOXIN RACE CONOPEPTIDE CONUS striatus O-superfamily conotoxin. 
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