Supported by the National Natural Science Foundation of China(No.42176101);the Ningbo Youth Science and Technology Innovation Leading Project(No.2024QL063);the National 111 Project of China(No.D16013);the Scientific Research Fund of Zhejiang Provincial Education Department(No.Y202250186);the Li Dak Sum Yip Yio Chin Kenneth Li Marine Biopharmaceutical Development Fund。
Marine natural products offer a promising source in the development of new antibiotic drugs.Two previously undescribed compounds,including one sulfur-bearing alkaloid named quinosumycin(1)along with one chromone deriv...
A novel quinazolinone derivative ethyl 2-(2-methyl-4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)ace-tate(EMOTA)was synthesized and characterized by HRMS,^(1)H NMR,^(13)C NMR spectroscopy and X-ray crystal-lography,and the ...
Supported by the Guilin scientific research and technological development program(No.20110330);the project of education department of Guangxi province(No.YB2014331);the Natural Science Foundation of Guangxi Province(2014GXNSFAA118035)
The title complexes based on 4(3H)-quinazolinone ligand have been synthesized and characterized by elemental analysis, IR spectrum and single-crystal X-ray diffraction analysis.Complex 1 belongs to the triclinic sys...
Financial support from the National Natural Sciences Foundation of China (NNSFC; Grant Nos. 81373287 and 30825044);the Beijing Excellent Talent Training Project (Grant No. 2013D009008000002);the National Science and Technology Project of China (Nos. 2012ZX09301002-002 and 2011ZX0 9307002-01)
Three pairs of enantiomerically pure alkaloids with diverse structure features, named isatindigoticoic acid A and epiisatindigoticoic acid A [(—)-1 and(+)-1], phaitanthrin A and epiphaitanthrin A [(—)-2 and(+)-2], a...
support from the National Natural Science Foundation of China(Nos.21332007 and 21472153);the Program for Changjiang Scholars and Innovative Research Team in University(PCSIRT)of Ministry of Education.
We report the concise and protecting-group-free enantioselective total syntheses of circumdatins F and H.In view of the extreme importance of analogs of quinazolinone alkaloids in drug research and discovery,four anal...
the National Natural Science Foundation of China (Nos.21302188,81072576,91027033);Chinese Academy of Sciences (Nos.KJCX2-EW-N06-01 and XDA09030307) for financial support
A novel method for achieving a copper(II)-catalyzed domino reaction for the construction of 2-aryl quinazolinones,without the addition of any ligand and additive,has been developed.The domino reaction achieved N-(a...
Benzoxazinone 2 was prepared and reacted with formamide,acetamide,some primary aromatic amines and heterocyclic amines giving the corresponding quinazolone derivatives 3-15 respectively.The reaction of benzoxazinone 2...
A simple and convenient approach for the synthesis of tetraheterocyclic benzothiazolo-[2,3-b]-quinazolin-1-ones has been developed utilizing the MCR methodology, which involves the condensation of 2-aminobenzothiazole...
a research grant from the Higher Education Commission of Pakistan under project No. 4-279/PAK-US/HEC 2010-917
The title compound was synthesized from 3-(2-methylphenyl)-2-thioxo-2,3-dihy- droquinazolin-4(1H)-one (4) which was prepared from 2-methylaniline in two steps. The structure was supported by the spectroscopic da...