Project supported by the National Natural Science Foundation of China(Grant No.11675228);China Postdoctoral Science Foundation(Grant No.2015M572662XB).
Signal transduction is an important and basic mechanism to cell life activities.The stochastic state transition of receptor induces the release of signaling molecular,which triggers the state transition of other recep...
We would like to thank Prof. Florentin Woergoetter, Dr. Christian Tetzlaff and Dr. Tomas Kulvicius for helpful discussions. This work is supported by Chinese Natural Science Foundation with 31601145, the Fundamental Research Funds for the Central Universities, and the Federal Ministry of Education and Research (BMBF) Germany to the Goettingen Bernstein Center for Computational Neuroscience Project D1. Y.L. conceived the experiment(s), Z.Z. and Y.L. conducted the experiment(s), Y.L. and Z.Z. analyzed the results, Y.L. wrote the paper. All authors reviewed the manuscript. The authors declare no competing interest.
This study addresses the fundamental principle of inter-synaptic interactions in synaptic cross-talk through homosynaptic and heterosynaptic plasticity by studying the intrinsic calcium signaling dynamics in spines. B...
Alzheimer's disease(AD) is an irreversible and progressive neurodegenerative disorder with no known cure or clear understanding of the mechanisms involved in the disease process.Amyloid plaques,neurofibrillary tangles...