云南高校图书馆联盟文献共享服务平台- GENOTOXIC

GENOTOXIC: 作品数：57被引量：85H指数：6; 导出分析报告; 相关领域：医药卫生更多>>; 相关期刊：《Science Bulletin》《癌变．畸变．突变》《Current Medical Science》《Journal of Analytical Sciences, Methods and Instrumentation》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划俄罗斯基础研究基金中国博士后科学基金更多>>

Environmental toxicity assessment of chromium (III) oxide nanoparticles using a phytotoxic, cytotoxic, and genotoxic approach: 《Emerging Contaminants》2024年第2期76-82,共7页Uhram Song Kwon Soon Pyo Ho Hyun Song Sun ryung Lee Jieun Kim; Chromium(III)oxide nanoparticles(NPs)have a wide range of industrial applications,particularly in the production of lithium-ion batteries;however,the toxicity of these NPs has not been studied extensively.The phytotox...; 关键词：NANOPARTICLE Plant growth Cell viability Chromium(III)oxide NEPHROTOXICITY

Efficacy of Bee Products(Anzer Honey,Pollen and Propolis)in Detection and Healing of Damage Induced by Antidiabetic Drug Vildagliptin/Metformin Hydrochloride in Healthy Human Pancreatic Cells:Cytotoxic,Genotoxic and Biochemical Studies: 《Current Medical Science》2023年第6期1173-1182,共10页ÖzlemÖzdemir ZinetÇöl Ömer Ertürk; Ordu University Scientific Project Coordination Department(ODUBAP,No.B-2139).; Background and Objective Although drugs are powerful therapeutic agents,they have a range of side effects.These side effects are sometimes cellular and not clinically noticeable.Vildagliptin/metformin hydrochloride is...; 关键词：cell viability hTERT-HPNE Anzer bee products drug side effect diabetes mellitus

Cerium Oxide Nanoparticles Protect against Oxaliplatin Induced Testicular Damage: Biochemical, Histological, Immunohistochemical, and Genotoxic Study: 《Occupational Diseases and Environmental Medicine》2023年第1期1-29,共29页Dalia M. Amin Marwa T. Abaza Shimaa H. Ameen Ghada A. Elsammak Samar M. Reda; Oxaliplatin is a chemotherapeutic drug used for colorectal cancer treatment. The testicular toxic effect is one of its recorded toxicities which resulted in a few studies. Oxidative stress could be a direct cause of t...; 关键词：Cerium Oxide Nanoparticles OXALIPLATIN Oxidative Stress TESTIS Toxicity

N-acetyl cysteine alters the genotoxic and estrogenic properties of Alternaria toxins in naturally occurring mixtures被引量：1: 《Emerging Contaminants》2022年第1期30-38,共9页Georg Aichinger Dino Grgic Julia Beisl Francesco Crudo Benedikt Warth Elisabeth Varga Doris Marko; It is unclear if complex mycotoxin mixtures produced by Alternaria spp.act estrogenic and/or genotoxic under physiological conditions,particularly considering the co-occurrence with antioxidants in food.Thus,this stud...; 关键词：MYCOTOXIN DNA damage XENOESTROGEN Combinatory toxicology Food contaminant Mixture effects

Covalent organic nanospheres as a fiber coating for solid-phase microextraction of genotoxic impurities followed by analysis using GC-MS被引量：2: 《Journal of Pharmaceutical Analysis》2022年第4期583-589,共7页Yanfang Zhao Jingkun Li Hanyi Xie Huijuan Li Xiangfeng Chen; supported by the Key Research and Development Program of Shandong Province(Grant No.:2019GSF111001);the National Natural Science Foundation of China(Grant No.:21906096);the Youth Science Funds of the Shandong Academy of Sciences(Grant No.:2019QN009);the Youth Ph.D.Cooperation Funds of Qilu University of Technology(Shandong Academy of Sciences,Grant No.:2018BSHZ0029);the Program for Taishan Scholars of Shandong Province(Grant No.:tsqn202103099).; Covalent organic nanospheres(CONs)were explored as a fiber coating for solid-phase microextraction of genotoxic impurities(GTIs)from active ingredients(AIs).CONs were synthesized by an easy solutionphase procedure at...; 关键词：Covalent organic nanospheres Solid-phase microextraction Genotoxic impurities Gas chromatography-mass spectrometry

Assessment of phytotoxic, genotoxic and enzyme inhibition potential of Sterculia diversifolia: 《Journal of Traditional Chinese Medicine》2022年第4期595-603,共9页Fazle Rabbi Amir Zada Amna Nisar; OBJECTIVE:To evaluate Sterculia diversifolia stem bark and leaves for phytotoxic,genotoxic and enzymes inhibition potential.METHODS:Phytotoxic activity of both stem bark and leaves were screened using Lemna minor.The ...; 关键词：STERCULIA plant extracts phytotoxic mutagenicity tests ENZYMES

Potential Antidiabetic and Anti-Genotoxic Activities of Silver Nanoparticles of Alkaloid Extract of Rhazya stricta in Rat Animal Model: 《Phyton-International Journal of Experimental Botany》2021年第6期1749-1762,共14页Mohammed Ali Ashehri; In most of Arabian courtiers Rhazya stricta is extensively utilized in public medicine for several diseases treatment.In this study,crude alkaloid extract of R.stricta(CAERS)coated with silver nanoparticles(CAERS-AgNP...; 关键词：Diabetes Rhazya stricta nanotechnology gene expression DNA damage apoptosis

Antioxidant and antigenotoxic properties of Alpinia galanga,Curcuma amada,and Curcuma caesia: 《Asian Pacific Journal of Tropical Biomedicine》2021年第8期363-374,共12页Anish Nag Ritesh Banerjee Priya Goswami Maumita Bandyopadhyay Anita Mukherjee; Objective:To compare the antioxidant and anti-genotoxic properties of Alpinia(A.)galanga,Curcuma(C.)amada,and C.caesia.Methods:Cytotoxicity of ethanolic extracts of A.galanga,C.amada,and C.caesia at selected doses was...; 关键词：ZINGIBERACEAE ANTIOXIDANTS Anti-genotoxic Curcuma amada Alpinia galanga Curcuma caesia PHYTOCHEMICALS

Ultra-Sensitive LC-MS/MS Method for the Trace Level Quantification of Six Potential Genotoxic Nitrosamine Impurities in Telmisartan被引量：1: 《American Journal of Analytical Chemistry》2021年第6期227-240,共14页Kartheek Srinivas Chidella Vijaya Bharathi Dasari Jayashree Anireddy; Nitrosamine impurities are potentially genotoxic which are considered under cohort of concern as per ICH M7 guidelines and need to be controlled at trace levels during quantification in drug substances and drug produc...; 关键词：NITROSAMINE NDMA GENOTOXIC LC-MS/MS TELMISARTAN IMPURITIES

A High Sensitive LC-MS/MS Method for the Simultaneous Determination of Potential Genotoxic Impurities Carboxy Phenyl Boronic Acid and Methyl Phenyl Boronic Acid in Lumacaftor: 《American Journal of Analytical Chemistry》2021年第3期74-86,共13页Kartheek Srinivas Chidella Vijaya Bharathi Dasari A. Jayashree; A simple, rapid, and highly sensitive LC-MS/MS method has been developed for the simultaneous and trace level quantification of underivatized boronic acids in lumacaftor active pharmaceutical ingredient. Chromatograph...; 关键词：Boronic Acid GENOTOXIC LC-MS/MS Lumacaftor

GENOTOXIC