TELMISARTAN

作品数：53被引量：175H指数：8
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相关领域：医药卫生更多>>
相关作者：祝春华李文赵勇乔会敏钟大放更多>>
相关机构：西安交通大学医学院第一附属医院沈阳药科大学河北医科大学第二医院复旦大学更多>>
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相关基金：国家自然科学基金国家高技术研究发展计划国家教育部博士点基金湖北省自然科学基金更多>>
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Bioequivalence Study of Two Formulations of Telmisartan 40 mg Tablets in Healthy Adult Bangladeshi Subjects under Fasting Conditions
《Advances in Bioscience and Biotechnology》2022年第9期419-427,共9页Alimur Reza Sabrina Akter Tushi Nithon Chandra Sahana Uttom Kumar Bhowmik Abdullah Al Shafi Majumder Arifa Akram 
Background: Telmisartan is a highly variable drug which is used to treat hypertension. This study compared to compare the bioavailability of two 40 mg Telmisartan tablets in adult and healthy Bangladeshi subjects. Mat...
关键词：BIOEQUIVALENCE TELMISARTAN Micardis Pharmacokinetics 
Application Effect Evaluation of Telmisartan combined with Spironolactone after Catheter Ablation of Patients with Paroxysmal Atrial Fibrillation
《Journal of Clinical and Nursing Research》2021年第3期135-139,共5页Rongcheng Zhao Jia Han Lei Zhao 
Observational study on effect of transcatheter radiofrequency ablation on patients with different types of atrial fibrillation(Project No.:172302089)。
Objective:To evaluate the application effect of telmisartan combined with spironolactone after catheter ablation of patients with paroxysmal atrial fibrillation.Methods:80 cases of patients with paroxysmal atrial fibr...
关键词：Paroxysmal atrial fibrillation Catheter ablation Telmisartan combined with spironolactone Application effect 
Telmisartan Attenuates the Growth of Epithelium-like Cells and Glomerular Injury in Spontaneously Hypertensive Rats被引量：1
《Current Medical Science》2021年第3期498-504,共7页Zhi ZHANG Fa-zhan WANG Zai-xin LI Xiang-rong SONG 
the General Financial Grant from the China Postdoctoral Science Foundation(No.2014M560722);the Natural Science Foundation of Sichuan University of Science and Engineering(No.2015RC30);the Science and Technology Support Program of Sichuan Province of China(No.2017RZ0083).
The abnormal growth of epithelium-like cells has been noticed in spontaneously hypertensive rats(SHRs)with hypertensive nephropathy.However,the characteristics of abnormal epithelium-like cells and their pathogenesis ...
关键词：HYPERTENSION epithelium-like cell glomerular injury TELMISARTAN spontaneously hypertensive rats(SHRs) 
Ultra-Sensitive LC-MS/MS Method for the Trace Level Quantification of Six Potential Genotoxic Nitrosamine Impurities in Telmisartan被引量：1
《American Journal of Analytical Chemistry》2021年第6期227-240,共14页Kartheek Srinivas Chidella Vijaya Bharathi Dasari Jayashree Anireddy 
Nitrosamine impurities are potentially genotoxic which are considered under cohort of concern as per ICH M7 guidelines and need to be controlled at trace levels during quantification in drug substances and drug produc...
关键词：NITROSAMINE NDMA GENOTOXIC LC-MS/MS TELMISARTAN IMPURITIES 
Antagonism of Angiotensin II AT1 Receptor and Silencing of CD44 Gene Expression Inhibit Cardiac Fibroblast Activation via Modulating TGF-<i>β</i>1/Smad Signaling Pathway
《Advances in Bioscience and Biotechnology》2020年第4期123-139,共17页Feng Bai Guangzhao Yang Joshua Robert Eskew Ningping Wang Himangshu Bose Zhiqing Zhao 
Angiotensin II (Ang II) is known to elicit cardiac fibrosis by activating the AT1 receptor and CD44 expression in the in vivo model. However, the cellular/molecular mechanisms underlying cardiac fibrosis are still not...
关键词：Angiotensin II AT1 Receptor CD44 Collagen Fibroblasts TELMISARTAN 
Telmisartan induces melanoma cell apoptosis and synergizes with vemurafenib in vitro by altering cell bioenergetics被引量：4
《Cancer Biology & Medicine》2019年第2期247-263,共17页Jelena Grahovac Tatjana Srdic-Rajic Juan Francisco Santibanez Marijana Pavlovic Milena Cavic Sinisa Radulovic1 
supported by grants from the Serbian Ministry for Education, Science and Technology Development (Grant No.III41026 and 175053)
Objective: Despite recent advancements in targeted therapy and immunotherapies, prognosis for metastatic melanoma patients remains extremely poor. Development of resistance to previously effective treatments presents ...
关键词：MELANOMA TELMISARTAN apoptosis MITOCHONDRIA reactive oxygen species targeted therapy 
Beneficial effects of losartan or telmisartan on the local hepatic renin-angiotensin system to counter obesity in an experimental model被引量：1
《World Journal of Hepatology》2019年第4期359-369,共11页Francielle Graus-Nunes Felipe de Oliveira Santos Thatiany de Souza Marinho Carolline Santos Miranda Sandra Barbosa-da-Silva Vanessa Souza-Mello 
Fundacao Carlos Chagas Filho de Apoio aPesquisa do Estado do Rio de Janeiro,No.E-26/202.888/2015 for V.S-M
BACKGROUND Obesity has been associated with hepatic overexpression of the renin-angiotensin system(RAS).AIM To evaluate the action of two angiotensin II(ANGII) receptor blockers(losartan or telmisartan) on the modulat...
关键词：Liver TELMISARTAN LOSARTAN OBESITY Angiotensin Ⅱ type 1 receptor C57BL/6 mouse 
Development and validation of a high throughput LC–MS/MS method for simultaneous quantitation of pioglitazone and telmisartan in rat plasma and its application to a pharmacokinetic study
《Journal of Pharmaceutical Analysis》2017年第6期381-387,共7页Pinaki Sengupta Bappaditya Chatterjee Uttam Kumar Mandal Bapi Gorain Tapan Kumar Pal 
Management of cardiovascular risk factors in diabetes demands special attention due to their co-existence. Pioglitazone （PIO） and telmisartan （TLM） combination can be beneficial in effective control of cardiovascu...
关键词：LC-MS/MS Rat plasma Pharmacokinetic applicability TELMISARTAN PIOGLITAZONE Pharmacokinetic application 
Effects of telmisartan combined with nifedipine controlled release tablet on inflammatory factors, vascular endothelial function and left ventricular function in patients with coronary heart disease with mild to moderate hypertension
《Journal of Hainan Medical University》2017年第20期14-18,共5页Feng Guo Bao-Wei Zhang Zheng-Yan Zhu 
Objective: To investigate the effect of telmisartan combined with Nifedipine Controlled Release Tablet on inflammatory factors, vascular endothelial function and left ventricular function in patients with coronary hea...
关键词：Coronary heart disease with mild to moderate hypertension TELMISARTAN NIFEDIPINE Controlled Release Table Inflammatory factors Vascular ENDOTHELIAL FUNCTION Left VENTRICULAR FUNCTION 
Assessment of serum lipid metabolism index and cytokine levels in patients with type 2 diabetes mellitus complicated by coronary heart disease after telmisartan combined with lipid-lowering drug treatment
《Journal of Hainan Medical University》2017年第13期38-41,共4页Xin Wang 
Objective:To study the effect of telmisartan combined with lipid-lowering drug therapy on serum lipid metabolism index and cytokine levels in patients with type 2 diabetes mellitus complicated by coronary heart diseas...
关键词：Type 2 diabetes MELLITUS Coronary heart disease TELMISARTAN Lipid METABOLISM indexes 
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