supported by the National Natural Science Foundation of China(82071498,81871046,and 32161143022);STI2030-Major Projects(2022ZD0214500).
Persistent and maladaptive drug-related memories represent a key component in drug addiction.Converging evidence from both preclinical and clinical studies has demonstrated the potential efficacy of the memory reconso...
supported by the STI2030-Major Projects(2022ZD0204900);the National Natural Science Foundation of China(32071029 and 32271080);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB32020200);the Yunnan Provincial Science and Technology Department(202402AA310014).
Numerous studies on the formation and consolidation of memory have shown that memory processes are characterized by phase-dependent and dynamic regulation.Memory retrieval,as the only representation of memory content ...
Objective To explore the effect of propranolol combined with memory retrieval reconsolidation procedure on alcohol craving.Methods A total of 54 patients with alcohol dependence who met the diagnostic criteria for alc...
supported by the National Key Technology Research and Development Program of the Ministry of Science and Technology of China(2015BAI13B01)
Fear memory underlies anxiety-related disorders, including posttraumatic stress disorder(PTSD). PTSD is a fear-based disorder,characterized by difficulties in extinguishing the learned fear response and maintaining ex...
Dreaming is a ubiquitous phenomenon in human beings and has been discussed, researched, and hypothesized since a long time. The substrate, physiological mechanism, and function of dreaming have been explained by many ...
Association between the reward caused by consuming drugs and the context in which they are consumed is essential in the formation of morphine-induced conditioned place preference(CPP).Glucocorticoid receptor(GRs)activ...
Association between the reward caused by consuming drugs and the context in which they are consumed is essential in the formation of morphine-induced conditioned place preference (CPP). Glucocorticoid receptor (GRs) a...
Memory traces become labile at the time of retrieval, and this initiates two protein synthesis-dependent processes in the brain: extinction, which inhibits their further retrieval, and reconsolidation, which may enhan...
Activity-regulated cytoskeleton-associated protein (Arc/Arg3.1) was originally identified in patients with seizures. It is densely distributed in the hip-pocampus and amygdala in particular. Because the expression of ...