supported by the Zhongshan-Fudan Joint Innovation Center,Zhongshan,Guangdong Province,China(528437);the National Natural Science Foundation of China(82271258,82271248,82204830,81971056);Innovative Research Team of High-level Local Universities in Shanghai,Shanghai Municipal Science and Technology Major Project(2018SHZDZX01);ZJ Lab,Shanghai Center for Brain Science and Brain-Inspired Technology.
Cancer-induced bone pain(CIBP)is a type of ongoing or breakthrough pain caused by a primary bone tumor or bone metastasis.CIBP constitutes a specific pain state with distinct characteristics;however,it shares similari...
supported by the National Natural Science Foundation of China, Nos.81473577 (to CGM), 81903596 (to QW), 82004028 (to LJS);China Postdoctoral Science Foundation, No.2020M680912 (to LJS);Open Project of The Key Laboratory of Medicinal Resources and Natural Pharmaceutical Chemistry, The Ministry of Education of China,No.2019004 (to CGM);Science and Technology Innovation Project of Shanxi Colleges of China, Nos.2019L0728 (to QW);Cultivation Project of Shanxi Universtity of Chinese Medicine of China, No.2019PY130 (to QW)
Ras homolog(Rho)-associated kinases(ROCKs)belong to the serine-threonine kinase family,which plays a pivotal role in regulating the damage,survival,axon guidance,and regeneration of neurons.ROCKs are also involved in ...
supported by the Zhejiang Provincial Key Project of Research and Development(No.2019C03043);the National Natural Science Foundation of China(Nos.32030035,31870874,32000623,and 32100693);the Zhejiang Provincial Natural Science Foundation(No.LZ21C080001)of China。
Tertiary lymphoid structures(TLSs)are formations at sites with persistent inflammatory stimulation,including tumors.These ectopic lymphoid organs mainly consist of chemo-attracting B cells,T cells,and supporting dendr...
This work was supported by the National Natural Science Foundation of China(No.81930102 to Bo Yang);the National Natural Science Foundation of China(No.81773754 to Ling Ding).
Transient receptor potential(TRP)channels are one primary type of calcium(Ca^(2+))permeable channels,and those relevant transmembrane and intracellular TRP channels were previously thought to be mainly associated with...
Supported by the National Natural Science Foundation of China,No.81801804
BACKGROUND Hepatitis B virus (HBV) has been recognized as a leading cause of hepatocellular carcinoma (HCC). Numerous reports suggest that immune infiltration can predict the prognosis of HCC. Nonetheless, no creditab...
This study was supported by the Major Research Program of National Natural Science Foundation of China(No.91542108,81471513,and 31671200);the Shanghai Rising-Star Program 16QA1400800;the Innovation-oriented Science and Technology Grant from National Population and Family Planning Commission Key Laboratory of Reproduction Regulation(CX2017-2);the Program for Zhuoxue of Fudan University,China.
Endometriosis(EMS)is a chronic inflammatory and estrogen-dependent gynecological disease characterized by the presence of endometrial tissue outside the uterine cavity.Although it is a benign disease,EMS is tumor-like...
AIM: To disclose the mechanisms that accelerate or limit tumor invasion and metastasis in gastric cancer patients. METHODS: The heparanase expression, continuity of basement, degree of infiltration by dendritic cell...
Supported by a grant from Posteoctoral Sciences Foundation of China (No.2002031281).
Objective: Umbilical cord blood stem cell transplantation (CBSCT) has approached significant success in leukemia treatment, but it is associated with higher rates of delayed or failed engraftment and relapse. This ...
Supported by Natural Science Foundation of Heilongjiang Province, No.D0234
AIM: To investigate the morphological characterization of tumor infiltrating dendritic cells (TIDCs) and tumor infiltrating lymphocytes (TILs) in human rectal cancer. METHODS: Light and electron microscopy as we...