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CARBOXYPEPTIDASE: 作品数：13被引量：49H指数：3; 导出分析报告; 相关领域：医药卫生生物学更多>>; 相关作者：许菲杨海泉刘龙更多>>; 相关机构：江南大学更多>>; 相关期刊：《Transactions of Tianjin University》《Cellular & Molecular Immunology》《Journal of Pancreatology》《Acta Pharmacologica Sinica》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划更多>>

A novel Wnt/β-catenin signaling gene signature for progression and metastasis of gastric cancer: 《Oncology Research》2025年第5期1199-1215,共17页JIA CHEN FEI JIANG KAIYI NIU HAODONG ZHAO LI LI HONGZHU YU; funded by the Natural Science Research Project of Anhui Educational Committee(2023AH050650);the Research Fund Program of Anhui Medical University(2023xkj176).; Backgrounds:As cancer progresses through various stages of malignancy,metastasis,and drug resistance,the Wnt/-catenin signaling is frequently dysregulated.Despite advancements in medical technology and therapeutic str...; 关键词：Gastric Cancer(GC) Signature genes Prognosis Carboxypeptidase Z(CPZ) Adipocyte Enhancer Binding Protein 1(AEBP1)

Pancreatic biomarkers:role in diabetes mellitus: 《Journal of Pancreatology》2023年第4期169-177,共9页Sana Rafaqat Ramsha Hafeez Rida Mairaj Abeerah Saleem Saira Rafaqat; Diabetes mellitus refers to a group of diseases that cause high blood sugar levels.The most common type is type 2 diabetes,which is caused by insulin resistance and inadequate insulin production.However,diabetes can a...; 关键词：AMYLASE CARBOXYPEPTIDASE CHOLECYSTOKININ CHYMOTRYPSIN Diabetes Elastase-1 Lipase Pancreatic biomarkers Retinol-binding protein 4 SECRETIN Trypsin

Carboxypeptidase A6 Promotes the Proliferation and Migration of Hepatocellular Carcinoma by Up-regulating AKT Signaling Pathway被引量：1: 《Current Medical Science》2019年第5期727-733,共7页Qi-bo HUANG Hong-wei ZHANG Zhi-bin LIAO; supported by the State Key Project on Infectious Diseases of China(No.2018ZX10723204-003);the National Natural Science Foundation of China(No.81572855,No.81572427);the Graduates’Innovation Fund,Huazhong University of Science and Technology(No.5003540055).; Summary:Hepatocellular carcinoma(HCC)has a poor treatment prognosis and high mortality worldwide.Understanding the molecular mechanism underlying HCC development would benefit the identification of diagnostic biomarke...; 关键词：CARBOXYPEPTIDASE A6 HEPATOCELLULAR carcinoma PROLIFERATION MIGRATION AKT

Solid-Phase Enzymatic Peptide Synthesis to Produce an Antioxidant Dipeptide: 《Transactions of Tianjin University》2019年第3期276-282,共7页Yuyao Shan Mengfan Wang Wei Qi Rongxin Su Zhimin He; supported by National Key Scientific Instrument and Equipment Development Projects of China (No. 2012YQ090194);National High Technology Research and Development Program of China ("863" Program, No. 2013AA102204);National Natural Science Foundation of China (Nos. 21676191, 21476165, 21621004); Peptide bond synthesis is favorable to the production of bioactive small peptides. However, the abuse of toxic reagents remains an issue for chemical synthesis method, whereas the low product yield and purity limit th...; 关键词：SOLID-PHASE ENZYMATIC PEPTIDE synthesis CARBOXYPEPTIDASE Y Tyrosine-alanine Antioxidant activity

Kinetically Controlled Carboxypeptidase-Catalyzed Synthesis of Novel Antioxidant Dipeptide Precursor BOC-Tyr-Ala: 《Transactions of Tianjin University》2018年第6期513-521,共9页Yuyao Shan Wei Qi Mengfan Wang Rongxin Su Zhimin He; supported by Ministry of Science and Technology of China(No.2012YQ090194 and No.2013AA102204);the National Natural Science Foundation of China(No.21676191,No.21476165,and No.21621004); Recently, enzymatic peptide synthesis has drawn increasing attention due to its eco-friendly reagents and mild conditions, as compared to traditional chemical peptide synthesis. In this study, we successfully produced...; 关键词：Antioxidant dipeptide precursor Kinetic control Reaction kinetic model Enzymatic peptide synthesis

The carboxypeptidase D homolog silver regulates memory formation via insulin pathway in Drosophila: 《Protein & Cell》2016年第8期606-610,共5页Lu, Binyan Zhao, Yi Zhao, Jie Yao, Xiaoyang Shuai, Yichun Ma, Weiwei Zhong, Yi; Dear Editor, What is the molecular basis of memory formation？ Many genes have been implicated in this process, including those involved in neural cell adhesion, mRNA transport, translation control, and cAMP-PKA signa...

Abrogation of immune complex glomerulonephritis by native carboxypeptidase and pharmacological antagonism of the C5a receptor被引量：1: 《Cellular & Molecular Immunology》2016年第5期651-657,共7页Jessy J. Alexander Lee D. Chaves Anthony Chang Shruti Dighe Alexander Jacob Richard J. Quigg; Activation of complement generates C5a which leads to signaling through C5aR 1. This is tightly controlled, including by the plasma proteins factor H （FH） and carboxypeptidase N. Here we studied a chronic serum sick...; 关键词：C5A carboxypeptidase N factor H GLOMERULONEPHRITIS

Comparison of Substrate Specificity of <em>Escherichia Coli</em>p-Aminobenzoyl-Glutamate Hy-drolase with <em>Pseudomonas</em>Carboxypeptidase G: 《Advances in Enzyme Research》2014年第1期39-48,共10页Cassandra M. Larimer Dejan Slavnic Lenore D. Pitstick Jacalyn M. Green; Reduced folic acid derivatives support biosynthesis of DNA, RNA and amino acids in bacteria as well as in eukaryotes, including humans. While the genes and steps for bacterial folic acid synthesis are known, those ass...; 关键词：Folate p-Aminobenzoyl-Glutamate Hydrolase CARBOXYPEPTIDASE G Folate CATABOLISM

Early dynamic transcriptomic changes during preoperative radiotherapy in patients with rectal cancer: A feasibility study被引量：3: 《World Journal of Gastroenterology》2013年第21期3249-3254,共6页Stephane Supiot Wilfried Gouraud Loc Campion Pascal Jezéquel Bruno Buecher Josiane Charrier Marie-Francoise Heymann Marc-Andre Mahé Emmanuel Rio Michel Chérel; Supported by Ligue Contre le Cancer, Programme Hospitalier de Recherche Clinique (20-R6); AIM: To develop novel biomarkers of rectal radiotherapy, we measured gene expression profiles on biopsies taken before and during preoperative radiotherapy. METHODS: Six patients presenting with a locally advanced rec...; 关键词：CCL28 CLIC5 PDCD4 RAB27A TXNIP Protein METABOLISM CELL ADHESION CELL migration SPON1 CARBOXYPEPTIDASE E

Isolation and characterization of carboxypeptidase Ⅲ from germinating triticale grains被引量：2: 《Acta Biochimica et Biophysica Sinica》2009年第1期69-78,共10页Adam Drzymala Wieslaw Bielawski; Carboxypeptidase Ⅲ from germinating triticale grains was purified 434.2-fold with a six-step procedure including： homogenization, ammonium sulfate precipitation, cation-exchange chromatography on CM-cellulose, gel f...; 关键词：carboxypeptidase Ⅲ enzymatic properties GERMINATION TRITICALE

CARBOXYPEPTIDASE