CATABOLISM

作品数：70被引量：218H指数：9
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相关领域：医药卫生生物学更多>>
相关作者：王方李春微李融融于康更多>>
相关机构：华中农业大学北京协和医院浙江大学更多>>
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相关基金：国家自然科学基金广东省自然科学基金国家重点基础研究发展计划中国博士后科学基金更多>>
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Endosomal catabolism of phosphatidylinositol 4,5-bisphosphate is fundamental in building resilience against pathogens
《Protein & Cell》2025年第3期161-187,共27页Chao Yang Longfeng Yao Dan Chen Changling Chen Wenbo Li Hua Tong Zihang Cheng Yanling Yan Long Lin Jing Zhang Anbing Shi 
The National Key R&D Program of China(2021YFA1300302);the National Natural Science Foundation of China(32320103007,32130027);the National Science Fund for Distinguished Young Scholars(31825017);the Major Research Plan of the Natural Science Foundation of China(92154001)to A.Shi.
Endosomes are characterized by the presence of various phosphoinositides that are essential for defining the membrane properties.However,the interplay between endosomal phosphoinositides metabolism and innate immunity...
关键词：C.elegans RAB-10/Rab10 UNC-16/JIP3 sorting endosome EGL-8/PLC-β NHR-25/NR5A1/2 PI(4 5)P2 
Prognostic impact of hypernatremia for septic shock patients in the intensive care unit
《World Journal of Clinical Cases》2025年第7期28-38,共11页Mai-Qing Shi Jun Chen Fu-Hai Ji Hao Zhou Ke Peng Jun Wang Chun-Lei Fan Xu Wang Yang Wang 
Supported by The National Natural Science Foundation of China,No.82072130;Key Medical Research Projects in Jiangsu Province,No.ZD2022021;Suzhou Clinical Medical Center for Anesthesiology,No.Szlcyxzxj202102。
BACKGROUND Hypernatremia represents a significant electrolyte imbalance associated with numerous adverse outcomes,particularly in cases of intensive care unit(ICU)-acquired hypernatremia(IAH).Nevertheless,its relevanc...
关键词：HYPERNATREMIA Hypernatremia acquired in the intensive care unit Septic shock Persistent inflammation IMMUNOSUPPRESSION Catabolism syndrome Chronic critical illness Prognosis 
Why should lymphocytes immune profile matter in sepsis?
《World Journal of Critical Care Medicine》2025年第2期18-26,共9页Wagner Nedel Lílian R Henrique Luis Valmor Portela 
The global incidence of critical illness has been steadily increasing,resulting in higher mortality rates thereby presenting substantial challenges for clinical mana-gement.Among these conditions,sepsis stands out as ...
关键词：LYMPHOCYTES Neutrophil-to-lymphocyte ratio SEPSIS Septic shock Chronic critical illness Persistent inflammation immunosuppression and catabolism syndrome 
A herbal pair of Scutellaria barbata D.Don and Scleromitrion diffusum(Willd.)R.J.Wang induced ferroptosis in ovarian cancer A2780 cells via inducing heme catabolism and ferritinophagy
《Journal of Integrative Medicine》2024年第6期665-682,共18页Zhen Wang Min Liu Guang-xing Li Liu Zhang Kai-yue Ding Si-qi Li Bing-qing Gao Peng Chen Hyok-Chol Choe Lun-yue Xia Yu-tong Yang Yi Liu Xue Sui Jun-nan Ma Lin Zhang 
supported by the National Natural Science Foundation of China(No.81873195);the Applied Basic Research Program of Liaoning Province(No.2023JH2/101300103);the Liaoning Revitalization Talents Program(No.XLYC1907113);the Dalian Medical University Foundation for Teaching Reform Project of Undergraduate Innovative Talents Training(No.111807010303)。
Objective:Despite the combination of Scutellaria barbata D.Don and Scleromitrion diffusum(Willd.)R.J.Wang(SB-SD)being a recognized Chinese medicinal herbal pair that is commonly used in the treatment of ovarian cancer...
关键词：Scutellaria barbata D.Don Scleromitrion diffusum(Willd.)R.J.Wang Ovarian cancer Transcriptomic Proteomic Ferroptosis Heme catabolism Ferritinophagy 
Adipose ADM2 ameliorates NAFLD via promotion of ceramide catabolism
《Acta Pharmaceutica Sinica B》2024年第11期4883-4898,共16页Pengcheng Wang Song-Yang Zhang YongQiang Dong Guangyi Zeng Huiying Liu Xian Wang Changtao Jiang Yin Li 
National Key Research and Development Program of China(Nos.2020YFA0803801,2022YFA0806400,and 2018YFA0800701);National Natural Science Foundation of China(Nos.81921001 and 32200949);project funded by China Postdoctoral Science Foundation(BX20220021,China);Xin Du and Julian Heng(Remotely Consulting,Australia)provided professional English-language editing of this article(Certificate No.2Tv2Ry7I).
The adipose tissue of mammals represents an important energy-storing and endocrine organ, and its dysfunction is relevant to the onset of several health problems, including non-alcoholic fatty liver disease (NAFLD). H...
关键词：Non-alcoholicfatty liver disease Adiposetissue Lipid metabolism Adrenomedullin 2 CERAMIDE HIF2α ACER2 
BAT-tling oxidative stress through BCAA catabolism
《Life Metabolism》2024年第5期42-44,共3页Maria Delgado-Martin Qiaoqiao Zhang Lawrence Kazak 
supported by Canadian Institutes of Health Research(CIHR)project grants(PJT-159529,PJT-190219,and PJT-180557);a Natural Sciences and Engineering Research Council of Canada(NSERC)Discovery Grant(to L.K.).
Elevated circulating levels of branched-chain amino acids(BCAAs)are associated with the development of type 2 diabetes and obesity,diseases that can be countered by the energy dissipating(thermogenic)function of brown...
关键词：BCAA properties. HOMEOSTASIS 
DNA methylation controlling abscisic acid catabolism responds to light to mediate strawberry fruit ripening
《Journal of Integrative Plant Biology》2024年第8期1718-1734,共17页Yunfan Sun Xiaofang Yang Rongrong Wu Shouzheng Lv Yunduan Li Haoran Jia Yuying Yang Baijun Li Wenbo Chen Andrew C.Allan Guihua Jiang Yan-Na Shi Kunsong Chen 
supported by the National Key Research and Development Program of China (2022YFD2100100);National Natural Science Foundation of China (U23A20215, 32002004);the 111 Project (B17039);Fundamental Research Funds for the Central University (226-2024-00063)。
Phytohormones,epigenetic regulation and environmental factors regulate fruit ripening but their interplay during strawberry fruit ripening remains to be determined.In this study,bagged strawberry fruit exhibited delay...
关键词：ABA catabolism DNA methylation LIGHT RIPENING STRAWBERRY 
Ribonucleotide reductase subunit M1 blocks glucose catabolism via phosphorylation of pyruvate kinase M2 in human esophageal squamous cell cancer
《Genes & Diseases》2024年第3期69-71,共3页Jian Yang Lingxiao Wang Hui Sun Zhenxiang Zhao Yanchuan Ma Zhen Hu Liqin Zhai Yonggang Wang 
supported by the National Natural Science Foundation of China(No.82103175);the Natural Science Foundation of Shanxi Province,China(No.201901D111432,20210302123316,202103021224379).
Esophageal squamous cell cancer(EScC)is one of the malignant tumors with high morbidity and mortality all over the world.^(1) In recent years,combined chemotherapy has gradually been the effective treatment method for...
关键词：SQUAMOUS ESOPHAGEAL cancer 
Bioremediation of Textile Azo Dyes Amido Black 10B, Reactive Black 5, Reactive Blue 160 by Lentinus squarrosulus AF5 and Assessment of Toxicity of the Degraded Metabolites
《Advances in Microbiology》2024年第2期137-161,共25页Anshu Mathur Chandrachur Ghosh Partha Roy Ramasare Prasad Rajesh Pratap Singh 
Bioremediation is an eco-compatible and economical approach to counter textile dye menace. The isolated Lentinus squarrosulus AF5 was assessed for decolourization of textile azo dyes, and had shown ~93%, 88% and 70% d...
关键词：Lentinus squarrosulus AF5 Azo Dyes FTIR 1H NMR CATABOLISM CYTOTOXICITY 
Botrytis cinerea-induced F-box protein 1 enhances disease resistance by inhibiting JAO/JOX-mediated jasmonic acid catabolism in Arabidopsis被引量：1
《Molecular Plant》2024年第2期297-311,共15页Min Zhang Weiwei Li Tingyu Zhang Yueyan Liu Lijing Liu 
This work was supported by the Natural Science Foundation of China(32000224,to L.L.);the Natural Science Foundation of Shandong Province(ZR2021QC142,to W.L.).
Jasmonic acid(JA)is a crucial phytohormone that regulates plant immunity.The endogenous JA level is determined by the rates of its biosynthesis and catabolism in plants.The activation of JA biosynthesis has been well ...
关键词：plant immunity BFP1 JAO/JOXs JA catabolism ubiquitination-mediated degradation 
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