supported by Canadian Institutes of Health Research(CIHR)project grants(PJT-159529,PJT-190219,and PJT-180557);a Natural Sciences and Engineering Research Council of Canada(NSERC)Discovery Grant(to L.K.).
Elevated circulating levels of branched-chain amino acids(BCAAs)are associated with the development of type 2 diabetes and obesity,diseases that can be countered by the energy dissipating(thermogenic)function of brown...
supported by grants from the National Natural Science Foundation of China(Nos.81870549 and 82200932);Tianjin Key Medical Discipline(Specialty)Construction Project(No.TJYXZDXK-075C).
to persist into adulthood and be associated with many adverse health outcomes later in adulthood,including cardiovascular diseases and type 2 diabetes.[1]In utero exposure to“undernutrition”or“over-nutrition”plays...
This research was supported by grants from the National Key R&D Program of China(No.2017YFC1307401);the National Natural Science Foundation of China(No.81803227)。
To the Editor:Type 2 diabetes(T2D)showed increasing prevalence worldwide and put a huge burden on healthcare systems.[1]Branched-chain amino acids(BCAAs,including Leucine,Isoleucine,and Valine),a prominent group of es...
supported by the National Key Research and Development Program of China(2016YFD0500501);Agricultural Research Outstanding Talents and Innovation Team(2016-nybrc03);the Fundamental Research Funds for the Central Institute,the Agricultural Science and Technology Innovation Program(ASTIPIAS07)。
Aerial ammonia exposure leads to tissue damage and metabolic dysfunction.However,it is unclear how different organs are coordinated to defend against aerial ammonia exposure.Twenty-four pigs were randomly divided into...
supported by Hong Kong Research Grants Council(No.C4024-16W);National Natural Science Foundation of China(No.91939302);Health and Medical Research Fund,Hong Kong Government(No.05161746)。
The peroxisome proliferator-activated receptor(PPARδ)agonists are reported to improve insulin sensitivity,reduce glucose levels,and alleviate dysfunctional lipid metabolism in animal models of type 2 diabetes mellitu...