BCAA

作品数:69被引量:170H指数:8
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BAT-tling oxidative stress through BCAA catabolism
《Life Metabolism》2024年第5期42-44,共3页Maria Delgado-Martin Qiaoqiao Zhang Lawrence Kazak 
supported by Canadian Institutes of Health Research(CIHR)project grants(PJT-159529,PJT-190219,and PJT-180557);a Natural Sciences and Engineering Research Council of Canada(NSERC)Discovery Grant(to L.K.).
Elevated circulating levels of branched-chain amino acids(BCAAs)are associated with the development of type 2 diabetes and obesity,diseases that can be countered by the energy dissipating(thermogenic)function of brown...
关键词:BCAA properties. HOMEOSTASIS 
Maternal serum branched-chain amino acids in early pregnancy and offspring growth patterns from 1 year to 8 years of age
《Chinese Medical Journal》2024年第15期1876-1878,共3页Ninghua Li Junhong Leng Rui Zhang Hui Wang Weiqin Li Shuang Zhang Yijuan Qiao Jing Li Zhijie Yu Gang Hu Zhongze Fang Xilin Yang 
supported by grants from the National Natural Science Foundation of China(Nos.81870549 and 82200932);Tianjin Key Medical Discipline(Specialty)Construction Project(No.TJYXZDXK-075C).
to persist into adulthood and be associated with many adverse health outcomes later in adulthood,including cardiovascular diseases and type 2 diabetes.[1]In utero exposure to“undernutrition”or“over-nutrition”plays...
关键词:BCAA PREGNANCY OBESITY 
支链氨基酸代谢在癌症中作用的研究进展
《生命科学》2024年第6期787-796,共10页熊娟 全纯涛 谢妮 
国家自然科学基金项目(82172356)。
支链氨基酸(branched-chain amino acids,BCAA)在癌症中的代谢异常现象引起了广泛关注。支链氨基酸包括亮氨酸、异亮氨酸和缬氨酸,它们不仅是构建蛋白质的基本元素,还在癌症进展中扮演关键角色。大量研究发现BCAA代谢途径中的相关代谢...
关键词:BCAA代谢 癌症 研究进展 
根治术后口服支链氨基酸有可能改善患者长期预后:一项META分析
《进展》2023年第9期248-250,共3页黄俊杰 黄平 
背景:原发性肝肝细胞肝癌是世界上常见的恶性肿瘤,早期肝细胞癌有通过根治性治疗显著改善预后的可能,但术后的高复发率显著影响着患者的预后。支链氨基酸(BCAA,Branched-Chain Amino Acid)是一种营养类药品,部分研究提示BCAA可通过多种...
关键词:支链氨基酸(BCAA) 肝切除术 射频消融术 肝细胞癌 复发 META分析 
资讯
《食品界》2022年第10期141-141,共1页
1运动“电”量拉满电解质+BCAA支链氨基酸+“快”“慢”糖,硬核运动buff叠满。成分上,每瓶500mL的电解质含量≥700mg,提供的钾、钙、钠、镁、氯离子等微量元素是常规版本的3.5倍,能补充运动流失的水分和电解质。
关键词:支链氨基酸 BCAA 微量元素 电解质 氯离子 
BCAA代谢异常与癌症的相关性研究进展被引量:1
《现代临床医学》2022年第3期237-240,共4页柴鸥 侯志敏 崔冬青 
代谢重编码满足了更高的营养需求,调控肿瘤的许多致癌过程,导致肿瘤恶变。支链氨基酸(BCAA),例如缬氨酸、亮氨酸和异亮氨酸,作为氮供体,生成核苷酸等大分子,是人类癌细胞生长必不可少的。BCAA代谢改变的细胞自主和非自主作用与癌症进展...
关键词:支链氨基酸 代谢重编码 癌症 研究进展 
Association of branched-chain amino acid intake trajectory in adulthood with the risk of type 2 diabetes and its related risk factors
《Chinese Medical Journal》2022年第1期104-106,共3页Weiqi Wang Tianshu Han Wanying Hou Xiyun Ren Wei Duan Zhipeng Liu Changhao Sun 
This research was supported by grants from the National Key R&D Program of China(No.2017YFC1307401);the National Natural Science Foundation of China(No.81803227)。
To the Editor:Type 2 diabetes(T2D)showed increasing prevalence worldwide and put a huge burden on healthcare systems.[1]Branched-chain amino acids(BCAAs,including Leucine,Isoleucine,and Valine),a prominent group of es...
关键词:INTAKE BCAA DIETARY 
Aerial ammonia exposure induces the perturbation of the interorgan ammonia disposal and branched-chain amino acid catabolism in growing pigs被引量:2
《Animal Nutrition》2021年第4期947-958,共12页Shanlong Tang Chang Yin Jingjing Xie Jinglin Jiao Liang Chen Lei Liu Sheng Zhang Hongfu Zhang 
supported by the National Key Research and Development Program of China(2016YFD0500501);Agricultural Research Outstanding Talents and Innovation Team(2016-nybrc03);the Fundamental Research Funds for the Central Institute,the Agricultural Science and Technology Innovation Program(ASTIPIAS07)。
Aerial ammonia exposure leads to tissue damage and metabolic dysfunction.However,it is unclear how different organs are coordinated to defend against aerial ammonia exposure.Twenty-four pigs were randomly divided into...
关键词:Targeted metabolomics Ammonia exposure Ammonia disposal BCAA catabolism PIG 
杂合子亲属活体肝移植治疗儿童BCKDHB基因新复合突变枫糖尿病1例并文献复习被引量:2
《器官移植》2021年第5期588-594,共7页吴越 顾广祥 夏强 
国家自然科学基金青年科学基金项目(81700570)。
目的总结枫糖尿病的杂合子亲属活体肝移植治疗效果。方法1例男性3岁患儿,因发现枫糖尿病半年于2017年7月5日入院。患儿空腹状态出现阵发性口齿不清、下肢运动功能障碍半年,枫糖样体味明显,语言发育稍迟缓,无其他生长发育异常和智力缺陷...
关键词:枫糖尿病 活体器官捐献 杂合子 肝移植 支链α-酮酸脱氢酶(BCKDH) 支链氨基酸(BCAA) 基因突变 急性代谢事件 
Integrated metabolomics analysis of the effect of PPARδ agonist GW501516 on catabolism of BCAAs and carboxylic acids in diabetic mice被引量:1
《Chinese Chemical Letters》2021年第7期2197-2202,共6页Li Xiang Juan Nie Li Wang Yu Wang Jingchun Shi Juntong Wei Chi-Wai Lau Zongwei Cai Yu Huang 
supported by Hong Kong Research Grants Council(No.C4024-16W);National Natural Science Foundation of China(No.91939302);Health and Medical Research Fund,Hong Kong Government(No.05161746)。
The peroxisome proliferator-activated receptor(PPARδ)agonists are reported to improve insulin sensitivity,reduce glucose levels,and alleviate dysfunctional lipid metabolism in animal models of type 2 diabetes mellitu...
关键词:PPARΔ BCAAs BCAA metabolites Metabolomics Diabetic mice 
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