supported by grants from the Natural Science Foundation of China(No.82072265);the National Natural Science Foundation of China(No.82302513);Guangdong Basic and Applied Basic Research Foundation(Nos.2022A1515110546,2024A1515013281);Science and Technology Project of Guangzhou(No.2023A03J0801);the Science and Technology Project of Guangzhou(No.202201020276);the Fund of Innovation and Entrepreneurship Leading Team Project of Guangzhou(No.201809010009).
To the Editor:Current combined antiretroviral therapy(cART)can effectively suppress the plasma viral load in most people living with human immunodeficiency virus-1(HIV,PLWH).However,approximately 20-30%of PLWH undergo...
Supported by the National Natural Science Foundation of China,No.82070574。
BACKGROUND Whether patients with compensated cirrhosis and low-level viremia(LLV)of hepatitis B should receive antiviral therapy(AVT)is still controversial,and published results are inconsistent.AIM To investigate the...
supported by the Emmy Noether Programme of the German Research Foundation(DFG,project no.495793173).
In a recent article in Science,Leon Weinberger and colleagues report on successful proof-of-concept studies of a novel strategy to control HIV-1 infection by using interfering viral particles.1 This approach radically...
Background:Chikungunya virus(CHIKV)is an infectious agent that caused several outbreaks among different countries and affected approximately 1.3 million Indian populations.It is transmitted by Aedes mosquito–either A...
HIV infection is an emerging health issue in Libya, particularly among young adults. Human cytomegalovirus (HCMV) is a prevalent infectious agent that presents with subclinical and fatal diseases in immunosuppressed i...
supported by Innovation Groups of the National Natural Science Foundation of China(81721002);the China National Natural Science Foundation(82130019);the National Key R&D Program of China(2019YFC0840704).
Background and Aims:There is a lack of data supporting the notion that antiviral treatments can beneft children with chronic hepatitis B(CHB)having high viremia and normal or mildly elevated serum alanine aminotransfe...
the Ethics Committee of Guangzhou Eighth People's Hospital(202033166),and all participants provided written informed consent.
Some HIV-infected individuals receiving ART develop low-level viremia(LLV),with a plasma viral load of 50-1000 copies/mL.Persistent low-level viremia is associated with subsequent virologic failure.The peripheral bloo...
Objective To observe the efficacy and factors influencing sequential or combined tenofovir alafenamide fumarate(TAF)after treatment with entecavir(ETV)in patients with chronic hepatitis B(CHB)with low-level viremia(LL...
supported by the Key Research and Development Program of Hebei Province (No.19277779D);the Program of Introduce International Intelligence of Hebei Province,Medical technology tracking in Hebei Province (No.2019009);the Forth Batch of Top-talents of Hebei Province.
Background and Aims:The impact of nonalcoholic fatty liver disease(NAFLD)on the treatment outcome of chronic hepatitis B(CHB)is undefined and deserves an in-depth investigation.Methods:Histologically-proven CHB receiv...
Citation of this article:Corrigendum:Chronic Hepatitis B Infection with Low Level Viremia Correlates with the Progression of the Liver Disease.J Clin Transl Hepatol 2022;10(5):1011–1012.doi:10.14218/JCTH.2022.00425.