Supported by Slovenian Research Agency,Young Researcher Grant toŠalamon Arčan I,No.P1-0390,J3-4533,Z3-2653.
The global burden of psychopathologies appears to be underestimated,since the global psychiatric disorder burden is exceeding other medical burdens.To be able to address this problem more effectively,we need to better...
Supported by National Natural Science Foundation of China,No.81874279;Scientific and Technological Development Program of Jilin Province,No.20190201093JC and No.20200201326JC;Jilin Province Department of Finance,No.JLSWSRCZX2020-010;Youth Development Fund from First Hospital of Jilin University,No.JDYY11202021.
BACKGROUND Most gastric cancer(GC)patients are diagnosed at middle or late stage because the symptoms in early stage are obscure,which causes higher mortality rates of GC.Helicobacter pylori(H.pylori)was identified as...
To valorize kraft lignin,hydroxymethylation and sulfonation were applied on this under-utilized,but vastly available,material.The hydroxymethylation pretreatment was conducted as means to improve the reactivity of lig...
Background: DNA hydroxymethylation refers to a chemical modification process in which 5-methylcytosine (5mC) is catalyzed to 5-hydroxymethylcytosine (5hmC) by ten-eleven translocation (TET) family proteins. Rec...
supported by National Basic Research Program of China(Grant No.2011CB504201)
Objective: Kaiso is upregulated in many cancers and proposed to bind with both methylated- and unmethylated-DNA in the nucleus as a transcriptional repressor. The objective is to define its subcellnlar localization i...
Lignin was extracted from peat by Sosa Method. In order to increase its chemical activity, it is necessary to make a structural modification by hydroxymethylation so it can be used in preparation of synthetic wood. De...
supported by Natural Science Foundation of Xuzhou Normal University(No.08XLB08);Science and Technology Project of Xuzhou(No.XJ09078);Universities Natural Science Foundation of Jiangsu Province (No.09KJD 150006)
Hydroxymethylation of 6,8-O-dimethyl emodin was easily achieved in good yields by the modified Marschalk reaction.The influence of the amount of solvent,base and formaldehyde toward the hydroxymethylation was discusse...
Non-a-tocopherols are hydroxymethylated and hydrogenated to produce α-tocopherol in one pot process by simultaneously reacting with paraformaldehyde and hydrogen in the presence of catalysts of benzenesulfonic acid a...
A novel one-pot synthesis of 4,5-bis(hydroxymethyl) imidazoles 2a-b, new ethers 3a-b and a new type of imidazolophane 4b by the bis-hydroxymethylation of imidazole or 2-methyl imidazole with formaldehyde and potassium...