Aim: To investigate the role of crotoxin (CrTX)-induced autophagy in the death of MCF-7 cells, a caspase-3-deficient, human breast cancer cell line. Methods: Cultured MCF-7 cells were treated with various doses of...
the Natural Science Foundation of Jiangsu Province(No BK2002139).
Aim:To examine if isoflurane preconditioning can attenuate ischemia/reperfusion injury by reducing cytochrome c release from inner mitochondrial membrane. Methods:Isolated hearts of Sprague-Dawley rats were perfused o...
The secondary structures of native cytochrome c(cyt c) in both solid and solution states and four platinum modified cyt c derivatives in solution were determined by means of Fourier transform infrared spectroscopy. I...
Project supported by the National Natural Science Foundation of China
Cardiolipin (CL) with two negative charges and four unsaturated fatty acyl chains is a phosphalipid specific to mitochondrial inner membrane. With the static interaction cytochrome c can be bound to CL. Because of the...