ANTI-ANGIOGENESIS

作品数：79被引量：342H指数：9
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相关领域：医药卫生生物学更多>>
相关作者：王婷婷李文华王伟周建平更多>>
相关机构：上海交通大学医学院附属新华医院吉林大学中国药科大学更多>>
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相关基金：国家自然科学基金中国博士后科学基金广东省自然科学基金上海市教育委员会重点学科基金更多>>
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Combination of fruquintinib with venetoclax for the treatment of colorectal cancer
《Oncology Research》2025年第1期225-234,共10页WEI ZHANG WEICHENG WANG RUI WANG XIAO HAN LIJUN ZHU WENJIE GUO YANHONG GU 
supported by the National Natural Science Foundation of China(82072675,82273197,82173933);Fundamental Research Funds for the Central Universities(020814380160).
Background:As a novel blocker of vascular endothelial growth factor receptor(VEGFR),fruquintinib has been approved for treating colorectal cancer(CRC).However,its dosage and therapeutic efficacy are limited by its wid...
关键词：Colorectal cancer(CRC) B-cell lymphoma protein 2(BCL2) Venetoclax Vascular endothelial growth factor receptor(VEGFR) Fruquintinib ANTI-ANGIOGENESIS IMMUNOTHERAPY 
Landscape of transarterial chemoembolization represented interventional therapy for hepatocellular carcinoma
《World Journal of Gastrointestinal Surgery》2024年第12期3903-3906,共4页Yang-Yang Fu Wen-Mao Li Hong-Qiao Cai Yan Jiao 
This article discusses the article written by Tan et al.Transarterial chemoembol-ization(TACE)is one of the main treatment methods for advanced hepatocellular carcinoma(HCC).There are other vascular interventional the...
关键词：Transarterial chemoembolization Interventional therapy Hepatocellular carcinoma ANTI-ANGIOGENESIS IMMUNOTHERAPY Programmed cell death 1 
Bioengineered silver nanoparticles induced apoptosis through upregulation of caspase 3 and caspase 8 proteins in breast adenocarcinoma MDA-MB-231 cells and impede angiogenesis
《Particuology》2024年第12期252-264,共13页Shahnaz Majeed Nurul Izzah Binti Abu Bakar Mohammad Danish Afzan Binti Mahmad Mohamad Nasir Mohamad Ibrahim Norul Aini Zakariya Sreenivas Patro Sisinthy Ravindran Muthukumarasamy Abdulaziz M.Alanazi Mohammed Tahir Ansari Ohoud A.Jefri 
In recent years,a lot of research has been done on silver nanoparticles(SNP)due to their numerous applications in the biomedical,pharmaceutical,and drug delivery industries.In this present study SNP were green synthes...
关键词：Silver nanoparticles TEM ANTI-ANGIOGENESIS DAPI ROS 
Progress of Immunotherapy Combined with Anti-Angiogenesis Therapy in Lung Cancer
《Journal of Biosciences and Medicines》2024年第9期183-195,共13页Chenyang Zuo Jinyuan Xie Meng Wang Jun Cai Qingqing Ye 
Lung cancer is the most prevalent and fatal cancer in China and even around the world, and many patients are found in the late stage of lung cancer. For the treatment of advanced lung cancer, in addition to traditiona...
关键词：IMMUNOTHERAPY Anti-Angiogenic Therapy Lung Cancer Tumor Immune Microenvironment 
Gastric cancer secreted miR 214-3p inhibits the anti-angiogenesis effect of apatinib by suppressing ferroptosis in vascular endothelial cells被引量：4
《Oncology Research》2024年第3期489-502,共14页WEIXUE WANG TONGTONG WANG YAN ZHANG TING DENG HAIYANG ZHANG YI BA 
grants from the National Science Foundation of China(Nos.82173125,81974374,82072664,82103677);Tianjin Key Medical Discipline(Specialty)Construction Project(TJYXZDXK-009A);The Science&Technology Development Fund of Tianjin Education Commission for Higher Education(2020KJ127).
Diferent from necrosis,apoptosis,autophagy and other forms of cell death,ferroptosis is a mechanism that catalyzes lipid peroxidation of polyunsaturated ftty acids under the action of iron divalent or lipoxygenase,lea...
关键词：Cellular ferroptosis EXOSOME Tyrosine kinase inhibitor Gastrointestinal tumors miRNA 
Efficacy and safety of anlotinib combined with the STUPP regimen in patients with newly diagnosed glioblastoma: a multicenter, single-arm, phase Ⅱ trial
《Cancer Biology & Medicine》2024年第5期433-444,共12页Shuzhen Lai Peijing Li Xiaohui Liu Guihong Liu Tieming Xie Xing Zhang Xiaoxuan Wang Jing Huang Yiqiang Tang Zhigang Liu Guoping Shen Chaoming Li Fangxiao Lu Lei Wang Fagui Jiang Caixing Sun Yuanyuan Chen Ming Chen 
supported by the National Natural Science Foundation of China(Grant No.82272744);Natural Science Foundation of Guangdong Province(Grant No.2022A1515010814);Sun Yat-sen University Clinical Research 5010 Program(Grant No.2022008).
Objective:Glioblastomas are highly vascularized malignant tumors.We determined the efficacy and safety of the anti-angiogenic multi-kinase inhibitor,anlotinib,for a newly diagnosed glioblastoma.Methods:This multicente...
关键词：GLIOBLASTOMA ANTI-ANGIOGENESIS multi-kinase inhibitor anlotinib TEMOZOLOMIDE progression-free survival 
Targeted anti-cancer therapy: Co-delivery of VEGF siRNA and Phenethyl isothiocyanate (PEITC) via cRGD-modified lipid nanoparticles for enhanced anti-angiogenic efficacy被引量：1
《Asian Journal of Pharmaceutical Sciences》2024年第2期170-187,共18页Bao Li Haoran Niu Xiaoyun Zhao Xiaoyu Huang Yu Ding Ke Dang Tianzhi Yang Yongfeng Chen Jizhuang Ma Xiaohong Liu Keda Zhang Huichao Xie Pingtian Ding 
supported by Guangdong Basic and Applied Basic Research Foundation(2023A1515010969);Natural Science Foundation of Top Talent of SZTU(GDRC202305).
Anti-tumor angiogenesis therapy, targeting the suppression of blood vessel growth in tumors, presents a potent approach in the battle against cancer. Traditional therapies have primarily concentrated on single-target ...
关键词：ANTI-ANGIOGENESIS Tumor apoptosis Nanoparticles VEGF siRNA Hypoxia inducible factor(HIF)-1 protein Phenethyl isothi ocyanate(PEITC) 
Anlotinib in combination with Envolizumab plus Etoposide for the treatment of EX-SCLC:a case report
《Clinical Research Communications》2024年第1期29-33,共5页Hong-Lei Guo Hong Wang Yan-Qi Song Xin-Long Song Ai-Di Wang Bao-Shan Liu 
Background:Small cell lung cancer(SCLC)is an aggressive malignant tumor with strong immunosuppressive effects,characterized by rapid doubling time and poor prognosis.Currently,effective therapeutic options are urgentl...
关键词：Extensive-stage Small Cell Lung Cancer ANTI-ANGIOGENESIS PD-1 inhibitors Combined treatment case report 
Hepatic arterial infusion chemotherapy with anti-angiogenesis agents and immune checkpoint inhibitors for unresectable hepatocellular carcinoma and meta-analysis被引量：4
《World Journal of Gastroenterology》2024年第4期318-331,共14页Yu-Zhe Cao Guang-Lei Zheng Tian-Qi Zhang Hong-Yan Shao Jia-Yu Pan Zi-Lin Huang Meng-Xuan Zuo 
Supported by Natural Science Foundation of Guangdong Province,No.2020A1515011539.
BACKGROUND Hepatic arterial infusion chemotherapy(HAIC)has been proven to be an ideal choice for treating unresectable hepatocellular carcinoma(uHCC).HAIC-based treatment showed great potential for treating uHCC.Howev...
关键词：Unresectable hepatocellular carcinoma Hepatic arterial infusion chemotherapy Angiogenesis inhibitors Programmed cell death protein 1 Programmed death ligand 1 
Nanoscale coordination polymer Fe-DMY downregulating Poldip2-Nox4-H2O2 pathway and alleviating diabetic retinopathy被引量：1
《Journal of Pharmaceutical Analysis》2023年第11期1326-1345,共20页Si-Yu Gui Xin-Chen Wang Zhi-Hao Huang Mei-Mei Li Jia-Hao Wang Si-Yin Gui Gan-Hua Zhang Yao Lu Li-Ming Tao Hai-Sheng Qian Zheng-Xuan Jiang 
Diabetic retinopathy(DR)is a prevalent microvascular complication of diabetes and the leading cause of blindness and severe visual impairment in adults.The high levels of glucose trigger multiple intracellular oxidati...
关键词：Nano-coordinated polymer particles Bioactive molecules delivery ANTIOXIDANT ANTI-ANGIOGENESIS Diabetic retinopathy treatment 
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