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Carnitine palmitoyltransferase-II inactivity promotes malignant progression of metabolic dysfunction-associated fatty liver disease via liver cancer stem cell activation: 《World Journal of Gastroenterology》2024年第47期5055-5069,共15页Ling-Ling Wang Yu-Ming Lu Yi-Han Wang Yi-Fan Wang Rong-Fei Fang Wen-Li Sai Deng-Fu Yao Min Yao; Supported by the National Natural Science Foundation of China,No.32470985 and No.81673241.; BACKGROUND Metabolic dysfunction-associated fatty liver disease(MAFLD)is one of the main chronic liver diseases.However,the roles of mitochondrial carnitine palmitoyl transferase-II(CPT-II)downregulation and liver can...; 关键词：Metabolic dysfunction-associated fatty liver disease Carnitine palmitoyl transferase-II Mitochondria T lymphocytes Liver cancer stem cells

How the physical inactivity is affected by social-, economic- and physical-environmental factors: an exploratory study using the machine learning approach: 《International Journal of Digital Earth》2023年第1期2503-2521,共19页Kangjae Lee Jue Wang Joon Heo; supported by the Korea Institute of Energy Technology Evaluation and Planning(KETEP);the Ministry of Trade,Industry&Energy(MOTIE)of the Republic of Korea(No.2022000000150).; Previous studies have utilized regression models to investigate the impact of environmental factors on physical activity.However,such approaches are inadequate for data-driven analysis seeking to identify robust assoc...; 关键词：Physical inactivity environmental effects machine learning GIS

Can physical activity eliminate the mortality risk associated with poor sleep?A 15-year follow-up of 341,248 MJ Cohort participants被引量：4: 《Journal of Sport and Health Science》2022年第5期596-604,共9页Li-Jung Chen Mark Hamer Yun-Ju Lai Bo-Huei Huang Po-Wen Ku Emmanuel Stamatakis; PWK’s work is supported in part by the Ministry of Science and Technology (MOST 108-2410-H-018-028-MY3);funded by the National Health and Medical Research Council(NHMRC) through a Senior Research Fellowship。; Background:This study examined the joint associations of sleep patterns and physical activity(PA) with all-cause,cardiovascular disease(CVD),and cancer mortality.Methods:A total of 341,248 adults(mean age=39.7 years;m...; 关键词：Exercise Heart disease INACTIVITY INSOMNIA Sleep disorders

Human Adipose Stem Cells Exposed to Gamma Radiation and Inactivity (Stasis) Show Increased Cancer Markers and DNA Damage. A Preliminary Assessment of a Pharmaceutical Formulation to Reverse These Effects and Its Applications for Medical Radiotherapy and the Space Industry: 《Journal of Cancer Therapy》2022年第1期7-19,共13页E. Russell Vickers; Gamma radiation exposure and physical inactivity occur in medical radiotherapy patients and astronauts resulting in substantial deterioration of their health. At the molecular level, the radiation triggers elevated ma...; 关键词：ASTRONAUTS DNA Gamma Radiation RADIOTHERAPY Space Medicine Space Mining ANTI-AGING Stem Cells

Predictive value of blood concentration of biologics on endoscopic inactivity in inflammatory bowel disease:A systematic review被引量：1: 《World Journal of Gastroenterology》2021年第9期886-907,共22页Wan-Ting Cao Rong Huang Ke-Fang Jiang Xue-Hui Qiao Jing-Jing Wang Yi-Hong Fan Yi Xu; Supported by The National Natural Science Foundation of China,No.81473506;Zhejiang TCM Science and Technology Project,No.2019ZA056,No.2016ZA092,and No.2021ZA057.; BACKGROUND Although blood concentration of biologics is an important composition of disease management in inflammatory bowel disease(IBD)patients,complexity and uncertainty of biological management encourage many disp...; 关键词：Inflammatory bowel disease Biological blood concentration Endoscopic inactivity INFLIXIMAB ADALIMUMAB Vedolizumab

Egocentric social network correlates of physical activity被引量：3: 《Journal of Sport and Health Science》2020年第4期339-344,共6页Sonja Motteli Simone Dohle; Background:The social environment might play an important role in explaining people’s physical activity(PA)behavior.However,little is known regarding whether personal networks differ between physically active and phy...; 关键词：Egocentric network EXERCISE INACTIVITY Personal network Physical activity QUESTIONNAIRE Similarity/homogeneity

Correlation between breast cancer and lifestyle within the Gulf Cooperation Council countries:A systematic review被引量：1: 《World Journal of Clinical Oncology》2020年第4期217-242,共26页Lara Theresa Annette Tanner Kwok Leung Cheung; BACKGROUND In the six Gulf Cooperation Council countries(GCCCs),Bahrain,Saudi Arabia,Kuwait,Oman,Qatar and the United Arab Emirates,breast cancer(BC)is the greatest cause of cancer incidence and mortality.Obesity and ...; 关键词：Breast cancer OBESITY Physical INACTIVITY Females GULF Cooperation COUNCIL COUNTRIES

Inactivity of YGL082W in vitro due to impairment of conformational change in the catalytic center loop被引量：1: 《Science China Chemistry》2020年第2期237-243,共7页Lining Lu Yu Guo Tian Wang Lujun Liang Suwen Zhao Feng Wang Lei Liu; supported by the National Key Research and Development Program of China(2017YFA0505200);the National Natural Science Foundation of China(21532004,91753205,81621002,21621003);Shanghai Tech University; MINDY-1 is a recently discovered new family of deubiquitinating enzymes(DUB),but one of its yeast homologs,YGL082 W,does not show any DUB activity in vitro.Sequence alignment shows that YGL082 W possesses the correct ...; 关键词：deubiquitinating enzymes(DUB) ENZYMOLOGY X-ray crystal structure molecular dynamics

Generalized Weighted Exponential-Gompertez Distribution: 《Applied Mathematics》2020年第2期97-118,共22页Abd El-Moneim A. M. Teamah Hanan H. El-Damrawy Shaimaa M. T. Swan; Statistical analysis of lifetime data is a significant topic in social sciences, engineering, reliability, biomedical and others. We use the generalized weighted exponential distribution, as a generator to introduce a...; 关键词：Generalized Weighted Exponential-G Family Gombertez DISTRIBUTION Bonferroni and LORENZ Curves Conditional Moments Mean INACTIVITY Time Mean Residual Lifetime Maximum LIKELIHOOD ESTIMATORS

Development of a computer vision system to detect inactivity in group-housed pigs被引量：1: 《International Journal of Agricultural and Biological Engineering》2020年第1期42-46,共5页Christopher Chijioke Ojukwu Yaoze Feng Guifeng Jia Haitao Zhao Hequn Tan; The current study was finally supported by National Key R&D Program of China(2018YFD0500700);and Natural Science Foundation of Hubei Province(2018CFB099).; Excessive inactivity in farm animals can be an early indication of illness.Traditional way for detecting excessive inactivity in pigs relies on manual inspection which can be laborious and especially time-consuming.Th...; 关键词：Matlab computer vision SOWS machine vision depth image PIGS INACTIVITY

INACTIVITY