MOGROSIDE

作品数：9被引量：35H指数：3
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Mogroside V protects against acetaminophen-induced liver injury by reducing reactive oxygen species and c-jun-N-terminal kinase activation in mice
《World Journal of Hepatology》2025年第3期170-179,共10页Jia-Lin Shi Tian Sun Qing Li Chun-Mei Li Jun-Fei Jin Chong Zhang 
Supported by Guangxi Natural Science Foundation of China,No.2024GXNSFAA010040;Special Fund of the Central Government Guiding Local Scientific and Technological Development by Guangxi Science and Technology Department,No.GuikeZY21195024;National Natural Science Foundation of China,No.82260499 and No.82460463.
BACKGROUND High levels of acetaminophen(APAP)consumption can result in significant liver toxicity.Mogroside V(MV)is a bioactive,plant-derived triterpenoid known for its various pharmacological activities.However,the i...
关键词：ACETAMINOPHEN Mogroside V Reactive oxygen species Liver injury C-jun-N-terminal kinase 
Mogroside IIE,an in vivo metabolite of sweet agent,alleviates acute lung injury via Pla2g2a-EGFR inhibition
《Food Science and Human Wellness》2024年第1期299-312,共14页Weichao Lü Guoqing Ren Kuniyoshi Shimizu Renshi Li Chaofeng Zhang 
the National Natural Science Foundation(81773982,82003937);Youth Academic leaders of the Qinglan Project in Jiangsu province for financial support。
In the face of increasingly serious environmental pollution,the health of human lung tissues is also facing serious threats.Mogroside IIE(M2E)is the main metabolite of sweetening agents mogrosides from the anti-tussiv...
关键词：Mogroside IIE Acute lung injury Secreted phospholipase A2 type IIA(Pla2g2a) Epidermal growth factor receptor(EGFR) 
Potential Anticancer Effect of Bioactive Extract of Monk Fruit (Siraitia grosvenori) on Human Prostate and Bladder Cancer Cells
《Journal of Cancer Therapy》2023年第5期211-224,共14页Rogerio Haung Akhil Saji Muhammad Choudhury Sensuke Konno 
Prostate and bladder cancers are the two prevalent urological cancers, and several therapeutic options are currently available but the outcomes have not been satisfactory. To find the better therapeutic option, we inv...
关键词：Monk Fruit MOGROSIDE ANTICANCER Prostate Cancer Bladder Cancer Lakanto 
Effects of Mogroside V on Glucose and Lipid Metabolism in High Fat Diet Mice
《Medicinal Plant》2022年第3期36-38,42,共4页Riming WEI Haiping LIU 
Supported by Science and Technology Planning Project of Guangxi,China (Gui Ke AA19254025)
[Objectives]To explore the effects and mechanism of mogroside V(MV)on glucose and lipid metabolism in high-fat diet(HFD)mice.[Methods]The experiment fed mice with high-fat diet for 8 weeks,and 40 mice with successful ...
关键词：Mogroside V(MV) High fat diet(HFD) Glucose and lipid metabolism Insulin resistance 
A structural and data-driven approach to engineering a plant cytochrome P450 enzyme被引量：6
《Science China(Life Sciences)》2019年第7期873-882,共10页Dawei Li Yongshuo Ma Yuan Zhou Junbo Gou Yang Zhong Lingling Zhao Lida Han Sergey Ovchinnikov Ling Ma Sanwen Huang Per Greisen Yi Shang 
supported by the National Natural Science Foundation of China(31672171,81773597);Shenzhen municipal(JCYJ20160530191729620 to Y.S.)Dapeng district governments
Functional manipulation of biosynthetic enzymes such as cytochrome P450 s(or P450 s) has attracted great interest in metabolic engineering of plant natural products.Cucurbitacins and mogrosides are plant triterpenoids...
关键词：plant P450 ENGINEERING protein design ROSETTA amino acid CO-EVOLUTION CUCURBITACIN MOGROSIDE 
罗汉果甜苷ⅡA的分离鉴定含量测定及其降糖抗氧化活性研究被引量：4
《广西师范大学学报（自然科学版）》2019年第3期132-141,共10页黄四新 周先丽 牟俊飞 罗琴 黄晓 陈旭 梁成钦 
国家自然科学基金(31560100,81860621);广西科学研究与技术开发计划项目(桂科能1598025-18);广西自然科学基金(2017GXNSFAA198242);省部共建药用资源化学与药物分子工程国家重点实验室项目(CHEMR2017-B15)
为了研究罗汉果中甜苷成分的生物活性及资源含量,为其进一步开发利用提供实验依据,本文通过柱色谱技术,从罗汉果中分离出罗汉果甜苷ⅡA(mogrosideⅡA);利用核磁波谱(NMR),对mogrosideⅡA进行波谱数据归属;通过α-葡萄糖苷酶抑制活性和...
关键词：罗汉果 mogrosideⅡA HPLC-MS α-葡萄糖苷酶抑制活性 抗氧化活性 
Mogroside V inhibits LPS-induced COX-2 expression/ROS production and overexpression of HO-1 by blocking phosphorylation of AKT1 in RAW264.7 cells被引量：22
《Acta Biochimica et Biophysica Sinica》2019年第4期365-374,共10页Yong Li Luyan Zou Tao Li Dengni Lai Yanyang Wu Si Qin 
Natural Science Foundation of China (No. 31101268);Key Scientific Research Fund of Hunan Provincial Science and Technology Department (No. 2017NK2093);Double First-Class Construction Project of Hunan Agricultural University (No. SYL201802025).
Momordica grosvenori is a valuable edible plant with medicinal purposes, and it is widely used in medicated diets and traditional Chinese medicine in Asia. Mogroside V (MV), the main bioactive component from M. grosve...
关键词：MOGROSIDE V ANTI-INFLAMMATORY property HO-1 NF-kB AKT1 ROS 
Microwave Digestion Sample Hydride Generation-Atomic Fluorescence Spectrometry Determines Trace Selenium of Mogroside
《International Journal of Technology Management》2013年第7期128-130,共3页Xiujing Zhang 
0.2000g mogroside sample is digested by 7.0ml nitric acid and 3.0ml hydrogen peroxide, and generated by coprecipitation enrichment hydride - atomic fluorescence spectrometry determines trace selenium in it. Under opti...
关键词：Hydride Generation-Atomic Fluorescence Spectrometry MOGROSIDE SELENIUM 
Assignments of ~1H and ^(13)C NMR Signals of Mogroside Ⅳa被引量：3
《Journal of Chinese Pharmaceutical Sciences》2003年第4期196-200,共5页ZHANGJian-ye YANGXiu-wei 
Aim To investigate the structure of mogroside Ⅳa isolated from traditionalChinese medicine fructus mo-mordicae [fruits of Siraitia grosvenori (Swingle) C. Jeffery] andsummarize the NMR characteristics of the structur...
关键词：fructus momordicae mogroside Ⅳa triterpenoid saponin NMR spectrum ASSIGNMENT 
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