ODONTOBLAST

作品数：6被引量：12H指数：2
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相关领域：医药卫生生物学更多>>
相关作者：马逢乐付蕾何文喜王娟王志华更多>>
相关机构：第四军医大学更多>>
相关期刊：《Science China(Life Sciences)》《International Journal of Oral Science》《World Journal of Methodology》《Journal of US-China Medical Science》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Atp6i deficient mouse model uncovers transforming growth factor-β1/Smad2/3 as a key signaling pathway regulating odontoblast differentiation and tooth root formation被引量：2
《International Journal of Oral Science》2023年第3期390-400,共11页Jue Wang Abigail McVicar Yilin Chen Hong-Wen Deng Zhihe Zhao Wei Chen Yi-Ping Li 
supported by the National Institutes of Health[DE023813 and DE028264 to Y.P.L.,and AG056438 and AR070135 to W.C.];the UAB National Institutes of Health National Institute of Dental and Craniofacial Research[Dental Academic Research Training Grant(DART)5T90DE022736 to J.W.].
The biomolecular mechanisms that regulate tooth root development and odontoblast differentiation are poorly understood.We found that Atp6i deficient mice(Atp6i^(−/−))arrested tooth root formation,indicated by truncate...
关键词：SMAD2/3 IMPAIRED prevention 
Phosphorylation of ATF2 promotes odontoblastic differentiation via intrinsic HAT activity
《Journal of Genetics and Genomics》2023年第7期497-510,共14页Huanyan Zuo Yao Xiao Jiahao Han Yuxiu Lin Cheng Tian Shu Zhang Guohua Yuan Huan Liu Zhi Chen 
supported by the National Natural Science Foundation of China (No. 82071110 and No. 82230029) to Zhi Chen;the National Natural Science Foundation of China (No. 82071077 and No.82270948);“the Fundamental Research Funds for the Central Universities”;“The Young Top-notch Talent Cultivation Program of Hubei Province” to Huan Liu
Mouse dental papilla cells(mDPCs)are cranial neural crest-derived dental mesenchymal cells that give rise to dentin-secreting odontoblasts after the bell stage during odontogenesis.The odontoblastic differentiation of...
关键词：ODONTOBLAST Dental papilla Mesenchymal stem cells ATF Transcription factors Cell differentiation Chromatin accessibility 
Odontoblast β-catenin signaling regulates fenestration of mouse Hertwig's epithelial root sheath被引量：8
《Science China(Life Sciences)》2015年第9期876-881,共6页ZHANG Ran TENG Yan ZHU Liang LIN JingTing YANG Xiao YANG Guan LI TieJun 
supported by grants from the State Key Program of the National Natural Science Foundation of China(81030018);the National Basic Research Program of China(2012CB966904);the National Natural Science Foundation of China(30900863,81241062)
The interaction between Hertwig＇s epithelial root sheath （HERS） and the adjacent mesenchyme is vitally important in mouse tooth root development. We previously generated odontoblast-specific Ctnnbl （encodingβ-cat...
关键词：Hertwig's epithelial root sheath β-catenin signaling BMP signaling mesenchyme-epithelium induction 
Nucleus-targeted Dmp1 transgene fails to rescue dental defects in Dmp1 null mice被引量：2
《International Journal of Oral Science》2014年第3期133-141,共9页Shu-Xian Lin Qi Zhang Hua Zhang Kevin Yan Leanne Ward Yong-Bo Lu Jian-Quan Feng 
supported by NIH grants DE018486 and R56 DE022789 to Jian-Quan Feng, DE023365 to Yong-Bo Lu and a scholarship from the Chinese State Scholarship Fund to Shu-Xian Lin (2010627108)
Dentin matrix protein 1（DMP1） is essential to odontogenesis. Its mutations in human subjects lead to dental problems such as dental deformities, hypomineralization and periodontal impairment. Primarily, DMP1 is cons...
关键词：autosomal recessive hypophosphatemic rickets dentin matrix protein 1 development ODONTOBLAST ODONTOGENESIS 
Adult stem cell-based apexogenesis
《World Journal of Methodology》2014年第2期99-108,共10页Yao Li Li-Hong Shu Ming Yan Wen-Yong Dai Jun-Jun Li Guang-Dong Zhang Jin-Hua Yu 
Supported by National Natural Science Foundation of China,No.81371144;Natural Science Foundation of Jiangsu Province,No.BK20131392;the Priority Academic Program Development of Jiangsu Higher Education Institutions PAPD,No.2011-137
Generally, the dental pulp needs to be removed when it is infected, and root canal therapy(RCT) is usually required in which infected dental pulp is replaced with inorganic materials(paste and gutta percha). This trea...
关键词：Apexogenesis DENTAL PULP STEM cell ODONTOBLAST TOOTH REGENERATION 
Myc Activates Telomerase in Human Odontoblast in vitro
《Journal of US-China Medical Science》2006年第3期14-18,共5页Hanguo Wang Mingzhen Xiao Shouliang Zhao Jianjun Hao Qing Yu 
Odontogenic differentiation and precise mechanism of dentinogenisis have not been well characterized partly because of the limited life span of native odontoblast. The ubiquitous transcription factor c-Myc, encoded by...
关键词：MYC TELOMERASE ODONTOBLAST 
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